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About Epalridase 50 mg Tablet
Epalridase 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.
Epalridase 50 mg Tablet contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epalridase 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.
You are advised to take Epalridase 50 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor before taking Epalridase 50 mg Tablet if you are pregnant or breastfeeding. Epalridase 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epalridase 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epalridase 50 mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Epalridase 50 mg Tablet

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Key Benefits
Epalridase 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors. Epalridase 50 mg Tablet is used for the management of diabetic neuropathy. Epalridase 50 mg Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Epalridase 50 mg Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).
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Drug Warnings
Do not take Epalridase 50 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Epalridase 50 mg Tablet if you are pregnant or breastfeeding. Epalridase 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Epalridase 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Epalridase 50 mg Tablet as it could lead to increased drowsiness and sleepiness.
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Alcohol
Safe if prescribed
Avoid consumption of alcohol while taking Epalridase 50 mg Tablet as it may cause increased dizziness.
Pregnancy
Consult your doctor
Limited information is available regarding the use of Epalridase 50 mg Tablet in pregnant women. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Limited information is available regarding the use of Epalridase 50 mg Tablet in breastfeeding women. Consult your doctor before taking Epalridase 50 mg Tablet ; your doctor will decide whether Epalridase 50 mg Tablet can be taken by breastfeeding mothers or not.
Driving
Safe if prescribed
Epalridase 50 mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.
Liver
Consult your doctor
Epalridase 50 mg Tablet should not be used in patients with severe liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Epalridase 50 mg Tablet should be used with caution in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Epalridase 50 mg Tablet should not be given to children as safety and efficacy have not been established.
Epalridase 50 mg Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Epalridase 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.
Diarrhoea could be a side-effect of Epalridase 50 mg Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.
Epalridase 50 mg Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Epalridase 50 mg Tablet . Regularly monitor blood pressure levels while taking Epalridase 50 mg Tablet .
Do not discontinue Epalridase 50 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Epalridase 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Epalridase 50 mg Tablet .
Epalridase 50 mg Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
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