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  1. Home
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  3. Eparel 50 mg Tablet 10's

Eparel 50 mg Tablet 10's, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

EPALRESTAT-50MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Eparel 50 mg Tablet

Eparel 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

Eparel 50 mg Tablet contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Eparel 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

You are advised to take Eparel 50 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Eparel 50 mg Tablet if you are pregnant or breastfeeding. Eparel 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Eparel 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Eparel 50 mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Eparel 50 mg Tablet

Diabetic neuropathy (diabetic nerve pain)

Directions for Use

Swallow Eparel 50 mg Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Eparel 50 mg Tablet belongs to a group of medicines called aldose reductase inhibitors. Eparel 50 mg Tablet is used for the management of diabetic neuropathy. Eparel 50 mg Tablet works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. Eparel 50 mg Tablet prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Eparel 50 mg Tablet if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking Eparel 50 mg Tablet if you are pregnant or breastfeeding. Eparel 50 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Eparel 50 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Eparel 50 mg Tablet as it could lead to increased drowsiness and sleepiness.

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Eparel 50 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Eparel 50 mg Tablet works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. Eparel 50 mg Tablet prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of Eparel 50 mg Tablet . Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

Eparel 50 mg Tablet might cause high blood pressure. So, if you have hypertension, consult your doctor before taking Eparel 50 mg Tablet . Regularly monitor blood pressure levels while taking Eparel 50 mg Tablet .

Do not discontinue Eparel 50 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Eparel 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Eparel 50 mg Tablet .

Eparel 50 mg Tablet may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. If you have diabetes and experience numbness, pain, tingling sensation, or weakness in the hands or legs, you must consult a doctor. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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