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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Epival Tablet

Epival Tablet belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Epival Tablet is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
­ 
Epival Tablet contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Epival Tablet increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take Epival Tablet with or without food. You are advised to take Epival Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Epival Tablet without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first-period whilst on treatment with Epival Tablet . Do not take Epival Tablet if you are pregnant as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Epival Tablet . Consult your doctor before taking Epival Tablet if you are breastfeeding. Do not drive or operate machinery as Epival Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Epival Tablet as it could lead to increased dizziness and sleepiness.

Uses of Epival Tablet

Epilepsy, Bipolar disorder, Migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not chew, or break the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe; shake the pack well before each use.

Medicinal Benefits

Epival Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Epival Tablet is also used to treat bipolar disorder and prevent migraine headaches. Epival Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Epival Tablet is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epival Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Dry mouth
  • Tremors
  • Tiredness
  • Sleepiness
  • Headache
  • Weight gain
  • Hair loss

Drug Warnings

Do not take Epival Tablet if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking Epival Tablet . Contact your doctor if your child gets her first period during the treatment with Epival Tablet . Do not take Epival Tablet if you are pregnant unless prescribed by the doctor as it is pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking Epival Tablet if you are breastfeeding. Epival Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Epival Tablet as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateLeflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Epival Tablet:
Combining Sodium phenylbutyrate and Epival Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Epival Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Epival Tablet:
Co-administration of Leflunomide and Epival Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Epival Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Epival Tablet:
Co-administration of Lithium with Epival Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Epival Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Epival Tablet:
Co-administration of Teriflunomide and Epival Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Epival Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Epival Tablet:
Co-administration of Vorinostat with Epival Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Epival Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Epival Tablet:
The combined use of Ertapenem and Epival Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Epival Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Epival Tablet:
Co-administration of Epival Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Epival Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Epival Tablet:
Co-administration of Meropenam and Epival Tablet together can reduce the effect of Epival Tablet.

How to manage the interaction:
Co-administration of Meropenam and Epival Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Epival Tablet:
Using buprenorphine together with Epival Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Epival Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Epival Tablet:
Co-administration of Ketamine and Epival Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Epival Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Epival Tablet Substitute

Substitutes safety advice
  • Valparin 200 Delicious Pineapple Oral Solution 200 ml

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    0.66per tablet
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    0.66per tablet
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    by AYUR

    0.66per tablet
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  • Valparin 200 Alkalets Tablet 15's

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Epival Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

Epival Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Epival Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Epival Tablet without consulting your doctor. To treat your condition effectually, continue taking Epival Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Epival Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Epival Tablet works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Epival Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Epival Tablet might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Epival Tablet . In rare cases, Epival Tablet can be a contributing factor in male infertility.

Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.

Epival Tablet may change the results of liver enzymes, and urine and blood tests. Inform the person doing the tests that you are taking Epival Tablet .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • ACETAZOLAMIDE
  • LAMOTRIGINE
  • FELBAMATE
  • WARFARIN
  • ZIDOVUDINE
  • LOPINAVIR
  • RITONAVIR
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • NIMODIPINE
  • PROPOFOL
  • ESTROGEN
  • LEVONORGESTREL
  • MEFLOQUINE
  • CHLOROQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLONAZEPAM
  • DIAZEPAM
  • CHOLESTYRAMINE

Special Advise

  • Contact your doctor if your child gets her first-period whilst on treatment with Epival Tablet .
  • Epival Tablet might affect blood and urine tests. Inform the person doing the tests that you are taking Epival Tablet .
  • If you are of child-bearing age, use effective contraception without interruptions during your entire treatment with Epival Tablet .
  • Consult your doctor immediately if you become pregnant while taking Epival Tablet .

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 

Side effects of Epival Tablet
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
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