EPREX 3000IU INJECTION
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EPREX 3000IU INJECTION belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in persons with chronic kidney disease (CKD), patients affected with HIV, and those receiving chemotherapy for cancer (except for bone marrow or blood cells' cancer). Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.
EPREX 3000IU INJECTION contains a human-made protein known as 'Epoetin alfa' which works by providing signals to the bone marrow to make more red blood cells (RBCs). EPREX 3000IU INJECTION helps to reverse anaemia and reduce the need for blood transfusion. EPREX 3000IU INJECTION is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, EPREX 3000IU INJECTION stimulates the production of this protein in the bone marrow.
EPREX 3000IU INJECTION will be administered by a healthcare professional; do not self-administer. The most common side effects of EPREX 3000IU INJECTION are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these side effects of EPREX 3000IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to epoetin alfa or darbepoetin alfa, please inform your doctor before taking EPREX 3000IU INJECTION to avoid any complications. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be a sign that the body has stopped responding to EPREX 3000IU INJECTION. It is not known whether EPREX 3000IU INJECTION will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant and breastfeeding before starting treatment with this medicine. EPREX 3000IU INJECTION is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might be lost. Do not store in the freezer or the fridge.
EPREX 3000IU INJECTION is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn causes low red blood cells count causing anemia. This medicine is primarily indicated for treating anemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease, persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells cancer, and persons taking zidovudine to treat HIV(human immunodeficiency virus). EPREX 3000IU INJECTION is also used to reduce the need for red blood cell transfusions in adults having certain types of surgery. EPREX 3000IU INJECTION contains a protein 'Epoetin alfa' which works by providing signals to the bone marrow to make more red blood cells.
EPREX 3000IU INJECTION can enhance the risk of blood clots and serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may speed up tumor growth, or shorten remission or survival time in some people with certain types of cancer. Inform your doctor before taking EPREX 3000IU INJECTION if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take EPREX 3000IU INJECTION if you are pregnant or breastfeeding unless prescribed by the doctor. EPREX 3000IU INJECTION should not be given to children below 1 month of age, as safety and effectiveness have not been established. Do not use EPREX 3000IU INJECTION from a multi-dose vial when giving medicine to a baby. The multi-dose vial contains an ingredient (benzyl alcohol) that can cause serious side effects or death in very young infants or premature babies. EPREX 3000IU INJECTION may affect a person's ability to drive as it may cause convulsions during the initial days of treatment, so a person taking EPREX 3000IU INJECTION should avoid driving or operating any machine. Avoid consuming alcohol along with EPREX 3000IU INJECTION as it could lead to increased dizziness and sleepiness.
Drug-Drug Interactions: EPREX 3000IU INJECTION may have interaction with other chemotherapy drugs (thalidomide, carfilzomib, lenalidomide, pomalidomide), immunosuppressant medication (cyclosporine), antihypertensive medicines (captopril, benazepril, enalapril, lisinopril, moexipril).
Drug-Food Interactions: Avoid alcohol consumption while taking EPREX 3000IU INJECTION as it might cause increased dizziness and sleepiness.
Drug-Disease Interactions: EPREX 3000IU INJECTION may have interactions with disease conditions such as seizures, hemodialysis, hypertension, porphyria (liver disorders) and thrombotic events.
Anaemia: It occurs when the body has a lower amount of red blood cells or haemoglobin than normal haemoglobin (iron-rich protein responsible for allowing red blood cells to carry more oxygen from the lungs to the rest of the body). In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Symptoms of anaemia in chronic kidney disease include fatigue or tiredness, shortness of breath, ashen skin, weakness, body aches, chest pain, dizziness, fainting, fast or irregular heartbeat, headache, sleep problems, and trouble concentrating.
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Keep Refrigerated. Do not freeze.Prepaid payment required.
Alcohol
Unsafe
Avoid consumption of alcohol while taking EPREX 3000IU INJECTION as it may increase dizziness and sleepiness.
Pregnancy
Caution
Avoid taking EPREX 3000IU INJECTION if you are pregnant unless prescribed by a doctor as EPREX 3000IU INJECTION is a pregnancy category B drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks. If prescribed use only single-dose vials (the benzyl alcohol-free formulation) in pregnant women.
Breast Feeding
Caution
Consult your doctor before taking EPREX 3000IU INJECTION; your doctor will decide whether EPREX 3000IU INJECTION can be taken by breastfeeding mothers or not.
Driving
Caution
EPREX 3000IU INJECTION causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Caution
EPREX 3000IU INJECTION should not be given to neonates as the safety and efficacy have not been established.