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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy

About Epsolin ER 300 Tablet 30's

Epsolin ER 300 Tablet 30's belongs to the group of medicines called 'anticonvulsants' used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. Besides this, Epsolin ER 300 Tablet 30's may also be used to treat trigeminal neuralgia (facial nerve pain). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behaviour, and loss of awareness.

Epsolin ER 300 Tablet 30's contains 'Phenytoin sodium' which helps prevent neurons from working at a very fast speed, thereby preventing the brain cells from firing together rapidly in an uncontrolled way. As a result, Epsolin ER 300 Tablet 30's controls the overactivity of the brain cells that causes seizures. Epsolin ER 300 Tablet 30's slows down the electrical impulses in the nerves and reduces their ability to transmit pain. Thereby treats trigeminal neuralgia.

Take Epsolin ER 300 Tablet 30's with or without food. You are advised to take Epsolin ER 300 Tablet 30's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Epsolin ER 300 Tablet 30's may cause certain common side-effects such as weakness, drowsiness, dizziness, restlessness, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Epsolin ER 300 Tablet 30's for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Epsolin ER 300 Tablet 30's suddenly without consulting your doctor as it may lead to increased seizures. Avoid taking Epsolin ER 300 Tablet 30's if you are pregnant or breastfeeding unless prescribed by the doctor. Avoid alcohol consumption while taking Epsolin ER 300 Tablet 30's as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Epsolin ER 300 Tablet 30's

Epilepsy (fits).

Medicinal Benefits

Epsolin ER 300 Tablet 30's is an anticonvulsant used to control and prevent epilepsy (fits). Epsolin ER 300 Tablet 30's is also used to control and prevent fits during or after a severe head injury or brain surgery. Epsolin ER 300 Tablet 30's works by controlling overactivity of the brain that causes seizures (fits). Thereby, Epsolin ER 300 Tablet 30's helps in controlling epileptic fits involving spasms of the muscles and jerking. Epsolin ER 300 Tablet 30's may also be used to treat trigeminal neuralgia (facial nerve pain).

Side Effects of Epsolin ER 300 Tablet 30's

  • Weakness
  • Drowsiness
  • Dizziness
  • Restlessness
  • Constipation

Directions for Use

Oral Tablet/Capsule: Do not chew, break, or crush the tablet/capsule; swallow it as a whole with a glass of water. Take it at the same time every day.Oral Liquid: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please stop taking Epsolin ER 300 Tablet 30's and consult your doctor if you develop any skin rashes (Stevens-Johnson syndrome), swollen glands (anticonvulsant hypersensitivity syndrome-AHS), or have suicidal thoughts. Do not take Epsolin ER 300 Tablet 30's if you are allergic to any of its contents. Talk to your doctor if you have heart, kidney, or liver problems and diabetes before starting Epsolin ER 300 Tablet 30's. Avoid taking Epsolin ER 300 Tablet 30's if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Epsolin ER 300 Tablet 30's as it might cause unpleasant side effects. Intake of Epsolin ER 300 Tablet 30's may cause dizziness. So be cautious while driving or operating any heavy machinery. Notify your doctor if you are taking anti-HIV medicines (like delavirdine) before intake of Epsolin ER 300 Tablet 30's, as both might react with each other leading to serious conditions.

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

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PhenytoinCeritinib
Critical
PhenytoinIsavuconazole
Critical

Drug-Drug Interactions

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PhenytoinCeritinib
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Taking ceritinib with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinIsavuconazole
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Co-administration of Epsolin ER 300 Tablet 30's and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Epsolin ER 300 Tablet 30's is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using Epsolin ER 300 Tablet 30's together with Cimetidin may increase the effects of Epsolin ER 300 Tablet 30's.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Cimetidine can cause an interaction, consult a doctor before taking it. Contact a doctor if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using Epsolin ER 300 Tablet 30's together with cimetidine may increase the effects of Epsolin ER 300 Tablet 30's.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinRanolazine
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using ranolazine together with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinLurasidone
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using lurasidone together with Epsolin ER 300 Tablet 30's may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Epsolin ER 300 Tablet 30's is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using venetoclax together with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinPraziquantel
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using praziquantel together with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Epsolin ER 300 Tablet 30's with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using rilpivirine together with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Epsolin ER 300 Tablet 30's is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinSofosbuvir
Severe
How does the drug interact with Epsolin ER 300 Tablet 30's:
Using sofosbuvir together with Epsolin ER 300 Tablet 30's may significantly reduce the blood levels of sofosbuvir.

How to manage the interaction:
Although there is a possible interaction between Sofosbuvir and Epsolin ER 300 Tablet 30's, you can take these medicines together if prescribed by a doctor. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • LEVOTHYROXINE
  • DELAVIRDINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL
  • FOLIC ACID

Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, involving in a task, and smelling a strong odour are a few self-control methods to prevent seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly, and avoid stress by doing meditation or yoga.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Include Vitamin D-rich foods like fatty fish, mackerel, tuna, dairy products, orange juice, soy milk, cereals, beef liver, cheese, and egg yolks in your diet.
  • Also, it is advised to take folic acid and vitamin K-rich foods and supplements during pregnancy.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

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