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  3. Eptifab 20mg Injection 10ml

Eptifab 20mg Injection 10ml, Pack of 1 INJECTION
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

EPTIFIBATIDE-20MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Eptifab 20mg Injection

Eptifab 20mg Injection belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Eptifab 20mg Injection is used in the treatment of Acute coronary syndrome (ACS) in both patients who need to be managed medically and also people undergoing percutaneous coronary intervention (PCI) procedures. ACS is defined as a group of serious cardiac conditions wherein the blood flow to the heart decreases due to plaque formation. Eptifab 20mg Injection is also used in the treatment of patients undergoing urgent PCI procedures and also in patients undergoing intracoronary stenting.

Eptifab 20mg Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptifab 20mg Injection reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Eptifab 20mg Injection may cause certain side effects, such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, decreased platelet count, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Eptifab 20mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Eptifab 20mg Injection should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptifab 20mg Injection is known to cause bleeding problems. If you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptifab 20mg Injection immediately. Hence, close monitoring is needed for any bleeding conditions. Talk to your doctor before receiving Eptifab 20mg Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking Eptifab 20mg Injection. Eptifab 20mg Injection is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Eptifab 20mg Injection

Myocardial Infraction, Acute Coronary Syndrome.

Directions for Use

A trained healthcare professional will administer Eptifab 20mg Injection. Hence, do not self-administer.

Medicinal Benefits

Eptifab 20mg Injection contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptifab 20mg Injection results in reducing the risk of cardiovascular events like myocardial infarction (heart attack) and other cardiac events.

Storage

Store in a cool and dry place away from sunlight
Side effects of Eptifab 20mg Injection 10ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Do not receive Eptifab 20mg Injection if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptifab 20mg Injection is known to cause bleeding problems. However, if you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptifab 20mg Injection immediately. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Eptifab 20mg Injection if you had a recent severe injury or surgery due to the risk of severe bleeding problems. Before taking Eptifab 20mg Injection inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding due to serious foetal harm. Eptifab 20mg Injection is not recommended for children below 12 years of age as efficacy and safety have not been established. Talk to your doctor before receiving Eptifab 20mg Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems.

Drug-Drug Interactions

verifiedApollotooltip
EptifibatideProtamine
Critical
EptifibatideIbrutinib
Severe

Drug-Drug Interactions

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EptifibatideProtamine
Critical
How does the drug interact with Eptifab 20mg Injection 10ml:
Coadministration of protamine and Eptifab 20mg Injection 10ml may increase the risk of bleeding

How to manage the interaction:
Taking Eptifab 20mg Injection 10ml with Protamine is not recommended, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
EptifibatideIbrutinib
Severe
How does the drug interact with Eptifab 20mg Injection 10ml:
Co-administration of Ibrutinib with Eptifab 20mg Injection 10ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ibrutinib with Eptifab 20mg Injection 10ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
EptifibatideApixaban
Severe
How does the drug interact with Eptifab 20mg Injection 10ml:
Coadministration of Eptifab 20mg Injection 10ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Eptifab 20mg Injection 10ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
EptifibatidePrasugrel
Severe
How does the drug interact with Eptifab 20mg Injection 10ml:
Co-administration of Eptifab 20mg Injection 10ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Eptifab 20mg Injection 10ml can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EptifibatideDabigatran etexilate
Severe
How does the drug interact with Eptifab 20mg Injection 10ml:
Taking Dabigatran etexilate with Eptifab 20mg Injection 10ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Eptifab 20mg Injection 10ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Eptifab 20mg Injection Substitute

Substitutes safety advice

Product Substitutes

Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Eptifab 20mg Injection contains Eptifibatide (anti-glycoprotein IIb/IIIa receptor), which works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

Eptifab 20mg Injection is known to increase the risk of bleeding. However, if the patient has uncontrollable bleeding, discontinue the medicine immediately.

Eptifab 20mg Injection may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CELECOXIB
  • TRAMADOL
  • CLOPIDOGREL
  • ENOXAPARIN
  • RIVAROXABAN
  • ENALAPRIL
  • CAPTOPRIL
  • NIFEDIPINE
  • CILNIDIPINE
  • ATENOLOL
  • SOTALOL
  • WARFARIN
  • TIROFIBAN
  • ABCIXIMAB

Special Advise

  • Before administration of Eptifab 20mg Injection, a blood test for CBC, serum creatinine, platelet count, prothrombin time, ACT, and APTT should be done to check for any hemostatic abnormalities.
  • If heparin is given, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and form a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the heart's lack of blood and oxygen supply. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

Acute coronary syndrome: Acute coronary syndrome is a group of serious cardiac conditions wherein the blood flow to the heart decreases. It is most often caused due to plaque rupture or clot formation in the heart's arteries. The symptoms may include heart attack-like chest pressure, chest pressure while resting or doing light activity, or sudden heart stoppage.

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