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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Eptifab 75Mg/ 100 Ml Inj

Eptifab 75Mg/ 100 Ml Inj belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Eptifab 75Mg/ 100 Ml Inj is used in the treatment of Acute coronary syndrome (ACS) in both patients who need to be managed medically and also people undergoing percutaneous coronary intervention (PCI) procedures. ACS is defined as a group of serious cardiac conditions wherein the blood flow to the heart decreases due to plaque formation. Eptifab 75Mg/ 100 Ml Inj is also used in the treatment of patients undergoing urgent PCI procedures and also in patients undergoing intracoronary stenting.

Eptifab 75Mg/ 100 Ml Inj contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptifab 75Mg/ 100 Ml Inj reduces the risk of cardiovascular events like myocardial infarction (heart attack).

Eptifab 75Mg/ 100 Ml Inj may cause certain side effects, such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, decreased platelet count, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Eptifab 75Mg/ 100 Ml Inj. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Eptifab 75Mg/ 100 Ml Inj should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptifab 75Mg/ 100 Ml Inj is known to cause bleeding problems. If you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptifab 75Mg/ 100 Ml Inj immediately. Hence, close monitoring is needed for any bleeding conditions. Talk to your doctor before receiving Eptifab 75Mg/ 100 Ml Inj if you had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking Eptifab 75Mg/ 100 Ml Inj. Eptifab 75Mg/ 100 Ml Inj is not recommended for children below 12 years of age as efficacy and safety have not been established.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Eptifab 75Mg/ 100 Ml Inj

Myocardial Infraction, Acute Coronary Syndrome.

Medicinal Benefits

Eptifab 75Mg/ 100 Ml Inj contains Eptifibatide, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Eptifab 75Mg/ 100 Ml Inj results in reducing the risk of cardiovascular events like myocardial infarction (heart attack) and other cardiac events.

Side Effects of Eptifab 75Mg/ 100 Ml Inj

  • Bleeding
  • Nausea
  • Headache
  • Abdominal pain
  • Hypotension
  • Vomiting
  • Dizziness
  • Low platelet count
  • Pain at the site of injection

Directions for Use

A trained healthcare professional will administer Eptifab 75Mg/ 100 Ml Inj. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not receive Eptifab 75Mg/ 100 Ml Inj if you are allergic to it. It is contraindicated in patients who have active internal bleeding, history of bleeding diathesis within 30 days, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, renal failure, using another glycoprotein IIb/IIIa inhibitor, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, as it can cause serious adverse effects. Eptifab 75Mg/ 100 Ml Inj is known to cause bleeding problems. However, if you observe severe bleeding that cannot be controlled, it is advised to stop administering Eptifab 75Mg/ 100 Ml Inj immediately. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Eptifab 75Mg/ 100 Ml Inj if you had a recent severe injury or surgery due to the risk of severe bleeding problems. Before taking Eptifab 75Mg/ 100 Ml Inj inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding due to serious foetal harm. Eptifab 75Mg/ 100 Ml Inj is not recommended for children below 12 years of age as efficacy and safety have not been established. Talk to your doctor before receiving Eptifab 75Mg/ 100 Ml Inj if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems.

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Drug-Drug Interactions

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EptifibatideProtamine
Critical
EptifibatideDabigatran etexilate
Severe

Drug-Drug Interactions

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EptifibatideProtamine
Critical
How does the drug interact with Eptifab 75Mg/ 100 Ml Inj:
Coadministration of protamine and Eptifab 75Mg/ 100 Ml Inj may increase the risk of bleeding

How to manage the interaction:
Taking Eptifab 75Mg/ 100 Ml Inj with Protamine is not recommended, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
EptifibatideDabigatran etexilate
Severe
How does the drug interact with Eptifab 75Mg/ 100 Ml Inj:
Taking Dabigatran etexilate with Eptifab 75Mg/ 100 Ml Inj can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Eptifab 75Mg/ 100 Ml Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EptifibatideIbrutinib
Severe
How does the drug interact with Eptifab 75Mg/ 100 Ml Inj:
Co-administration of Ibrutinib with Eptifab 75Mg/ 100 Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Ibrutinib with Eptifab 75Mg/ 100 Ml Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
EptifibatideApixaban
Severe
How does the drug interact with Eptifab 75Mg/ 100 Ml Inj:
Coadministration of Eptifab 75Mg/ 100 Ml Inj and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Eptifab 75Mg/ 100 Ml Inj and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
EptifibatidePrasugrel
Severe
How does the drug interact with Eptifab 75Mg/ 100 Ml Inj:
Co-administration of Eptifab 75Mg/ 100 Ml Inj with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Eptifab 75Mg/ 100 Ml Inj can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Special Advise

  • Before administration of Eptifab 75Mg/ 100 Ml Inj, a blood test for CBC, serum creatinine, platelet count, prothrombin time, ACT, and APTT should be done to check for any hemostatic abnormalities.
  • If heparin is given, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and form a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the heart's lack of blood and oxygen supply. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

Acute coronary syndrome: Acute coronary syndrome is a group of serious cardiac conditions wherein the blood flow to the heart decreases. It is most often caused due to plaque rupture or clot formation in the heart's arteries. The symptoms may include heart attack-like chest pressure, chest pressure while resting or doing light activity, or sudden heart stoppage.

Eptifab 75Mg/ 100 Ml Inj Substitute

Substitutes safety advice
  • Unigrilin 75 mg Injection 100 ml

    98.72per tablet
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