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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Composition :

PHENYTOIN-300MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Eptoin 300 ER Tablet

Eptoin 300 ER Tablet belongs to the group of medicines called 'anticonvulsants' used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. Besides this, Eptoin 300 ER Tablet may also be used to treat trigeminal neuralgia (facial nerve pain). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behaviour, and loss of awareness.

Eptoin 300 ER Tablet contains 'Phenytoin' which helps prevent neurons from working at a very fast speed, thereby preventing the brain cells from firing together rapidly in an uncontrolled way. As a result, Eptoin 300 ER Tablet controls the overactivity of the brain cells that causes seizures. Eptoin 300 ER Tablet slows down the electrical impulses in the nerves and reduces their ability to transmit pain. Thereby treats trigeminal neuralgia.

Take Eptoin 300 ER Tablet with or without food. You are advised to take Eptoin 300 ER Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Eptoin 300 ER Tablet may cause certain common side-effects such as weakness, drowsiness, dizziness, restlessness, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Eptoin 300 ER Tablet for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Eptoin 300 ER Tablet suddenly without consulting your doctor as it may lead to increased seizures. Avoid taking Eptoin 300 ER Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Avoid alcohol consumption while taking Eptoin 300 ER Tablet as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Eptoin 300 ER Tablet

Epilepsy/Seizures, Trigeminal neuralgia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, break, or crush the tablet/capsule. Suspension/Syrup/Drops: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Eptoin 300 ER Tablet belongs to the group of anticonvulsant medicines called 'hydantoins' used to treat epilepsy/seizures. Eptoin 300 ER Tablet is also used to control and prevent fits during or after a severe head injury or brain surgery. Eptoin 300 ER Tablet works by controlling the overactivity of the brain cells that cause seizures (fits). Thereby, Eptoin 300 ER Tablet helps in controlling epileptic fits involving spasms of the muscles and jerking. Eptoin 300 ER Tablet may also be used to treat trigeminal neuralgia (facial nerve pain). Eptoin 300 ER Tablet slows down the electrical impulses in the nerves and reduces their ability to transmit pain. Thereby treats trigeminal neuralgia.

Storage

Store in a cool and dry place away from sunlight
Side effects of Eptoin 300 ER Tablet
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

Drug Warnings

Do not take Eptoin 300 ER Tablet if you are allergic to any of its contents. Stop taking Eptoin 300 ER Tablet and consult your doctor if you develop any skin rashes (Stevens-Johnson syndrome), swollen glands (anticonvulsant hypersensitivity syndrome - AHS) or have suicidal thoughts. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Eptoin 300 ER Tablet if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Eptoin 300 ER Tablet as it might cause unpleasant side effects. Let your doctor know if you have diabetes, as intake of Eptoin 300 ER Tablet affects the blood sugar level. Intake of Eptoin 300 ER Tablet may cause dizziness so be cautious while driving or operating any heavy machinery. Tell your doctor that you are taking anti-HIV medicine (like delavirdine) before intake of Eptoin 300 ER Tablet , as both might react with each other leading to serious conditions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Eptoin 300 ER Tablet:
Co-administration of Eptoin 300 ER Tablet and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Eptoin 300 ER Tablet is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Eptoin 300 ER Tablet:
Using lurasidone together with Eptoin 300 ER Tablet may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Eptoin 300 ER Tablet is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Eptoin 300 ER Tablet:
Using venetoclax together with Eptoin 300 ER Tablet may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Eptoin 300 ER Tablet with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 300 ER Tablet:
Using praziquantel together with Eptoin 300 ER Tablet may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Eptoin 300 ER Tablet with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 300 ER Tablet:
Taking ceritinib with Eptoin 300 ER Tablet may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Eptoin 300 ER Tablet with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 300 ER Tablet:
Using ranolazine together with Eptoin 300 ER Tablet may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Eptoin 300 ER Tablet with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Eptoin 300 ER Tablet:
Using rilpivirine together with Eptoin 300 ER Tablet may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Eptoin 300 ER Tablet is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Eptoin 300 ER Tablet:
Using Eptoin 300 ER Tablet together with cimetidine may increase the effects of Eptoin 300 ER Tablet.

How to manage the interaction:
Taking Eptoin 300 ER Tablet with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinHydrocodone
Severe
How does the drug interact with Eptoin 300 ER Tablet:
Coadministration of Eptoin 300 ER Tablet and Hydrocodone may lower the levels of Hydrocodone in your blood, which could make it less effective.

How to manage the interaction:
Although taking Eptoin 300 ER Tablet and Hydrocodone together can result in an interaction, it can be taken if your doctor has prescribed it. Do not exceed the doses or frequency and duration of use prescribed by a doctor. Avoid driving or operating hazardous machinery.
How does the drug interact with Eptoin 300 ER Tablet:
Coadministration of Eptoin 300 ER Tablet and bortezomib can lower the levels of bortezomib, which could decrease its effectiveness.

How to manage the interaction:
Although using Bortezomib and Eptoin 300 ER Tablet together can result in an interaction, they can be taken together if advised by a doctor. However, consult a doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Eptoin 300 ER Tablet works by controlling overactivity of the brain that causes seizures (fits). Thereby, Eptoin 300 ER Tablet helps in controlling epileptic fits involving spasms of the muscles and jerking.

Eptoin 300 ER Tablet can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Please do not stop taking Eptoin 300 ER Tablet without consulting your doctor as it may cause increased seizures. Continue taking Eptoin 300 ER Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Eptoin 300 ER Tablet .

Yes, Eptoin 300 ER Tablet may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.

Eptoin 300 ER Tablet may affect the breakdown of the blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. So, contact a doctor before using Eptoin 300 ER Tablet if you have diabetes.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ACETAMINOPHEN
  • IBUPROFEN
  • WARFARIN
  • CLOPIDOGREL
  • CARBAMAZEPINE
  • GABAPENTIN
  • PREGABALIN
  • DIAZEPAM
  • FLUOXETINE
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • SILDENAFIL
  • CHOLECALCIFEROL
  • FOLIC ACID
  • DELAVIRDINE

Special Advise

Your doctor may advise you to get regular blood tests to check for any abnormality of blood and test the amount of Eptoin 300 ER Tablet in your blood. 

 

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Trigeminal neuralgia: It is a condition affecting the trigeminal nerve in the face that causes painful sensations similar to electric shock on one side of the face. Symptoms include mild to severe facial pain often triggered by speaking, chewing, or brushing the teeth.

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