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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

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Composition :

PHENYTOIN-50MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Eptoin 50 mg Injection 5 x 2 ml

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Eptoin 50 mg Injection 5 x 2 ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Eptoin 50 mg Injection 5 x 2 ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Avoid driving or operating heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Eptoin 50 mg Injection 5 x 2 ml

Epilepsy/Seizures, Cardiac arrhythmia

Directions for Use

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eptoin 50 mg Injection 5 x 2 ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

Drug Warnings

Do not take Eptoin 50 mg Injection 5 x 2 ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Do not drive or operate heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug-Drug Interactions

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PhenytoinRanolazine
Critical
PhenytoinLurasidone
Critical

Drug-Drug Interactions

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PhenytoinRanolazine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using ranolazine together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinLurasidone
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using lurasidone together with Eptoin 50 mg Injection 5 x 2 ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Eptoin 50 mg Injection 5 x 2 ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinIsavuconazole
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Co-administration of Eptoin 50 mg Injection 5 x 2 ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Eptoin 50 mg Injection 5 x 2 ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using Eptoin 50 mg Injection 5 x 2 ml together with Cimetidin may increase the effects of Eptoin 50 mg Injection 5 x 2 ml.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Cimetidine can cause an interaction, consult a doctor before taking it. Contact a doctor if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinCeritinib
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Taking ceritinib with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using venetoclax together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using rilpivirine together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Eptoin 50 mg Injection 5 x 2 ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using Eptoin 50 mg Injection 5 x 2 ml together with cimetidine may increase the effects of Eptoin 50 mg Injection 5 x 2 ml.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinPraziquantel
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using praziquantel together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinTrimethoprim
Severe
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Co-administration of trimethoprim with Eptoin 50 mg Injection 5 x 2 ml may increase the blood levels and effects of Eptoin 50 mg Injection 5 x 2 ml.

How to manage the interaction:
Although there is an interaction between trimethoprim and Eptoin 50 mg Injection 5 x 2 ml, but can be taken together if prescribed by doctor. However, if you experience nausea, vomiting, twitching eye movements, blurred vision, difficult to speak, loss of balance or coordination, tremors (shaking of hands legs), and confusion contact your doctor immediately. Do not discontinue any medications without consulting to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Eptoin 50 mg Injection 5 x 2 ml Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Eptoin 50 mg Injection 5 x 2 ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Eptoin 50 mg Injection 5 x 2 ml helps in controlling epileptic fits.

Eptoin 50 mg Injection 5 x 2 ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Eptoin 50 mg Injection 5 x 2 ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.

Eptoin 50 mg Injection 5 x 2 ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.

Eptoin 50 mg Injection 5 x 2 ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Eptoin 50 mg Injection 5 x 2 ml.

Drug-Drug Interactions Checker List

  • DELAVIRDINE
  • ASPIRIN
  • ACETAMINOPHEN
  • WARFARIN
  • CLOPIDOGREL
  • GABAPENTIN
  • PREGABALIN
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • LEVOTHYROXINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL

Special Advise

Consult your doctor immediately if you have suicidal thoughts such as harming or killing yourself.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Cardiac arrhythmia: Cardiac arrhythmia is a condition in which the heartbeats are abnormal or irregular. It occurs when the electrical signals in the heart do not work properly. Symptoms may include palpitations (a feeling as if the heart is pounding), chest pain, fainting, and dizziness.

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