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  3. Eptoin 50 mg Injection 5 x 2 ml

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Composition :

PHENYTOIN-50MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Eptoin 50 mg Injection 5 x 2 ml

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Eptoin 50 mg Injection 5 x 2 ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Eptoin 50 mg Injection 5 x 2 ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Avoid driving or operating heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Eptoin 50 mg Injection 5 x 2 ml

Epilepsy/Seizures, Cardiac arrhythmia

Directions for Use

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Storage

Keep Eptoin 50 mg Injection 5 x 2 ml out of reach and sight of children.
Side effects of Eptoin 50 mg Injection 5 x 2 ml
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.

Drug Warnings

Do not take Eptoin 50 mg Injection 5 x 2 ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Do not drive or operate heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Co-administration of Eptoin 50 mg Injection 5 x 2 ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Eptoin 50 mg Injection 5 x 2 ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using lurasidone together with Eptoin 50 mg Injection 5 x 2 ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Eptoin 50 mg Injection 5 x 2 ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using praziquantel together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Taking ceritinib with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinRilpivirine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using rilpivirine together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Eptoin 50 mg Injection 5 x 2 ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using ranolazine together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using venetoclax together with Eptoin 50 mg Injection 5 x 2 ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using Eptoin 50 mg Injection 5 x 2 ml together with cimetidine may increase the effects of Eptoin 50 mg Injection 5 x 2 ml.

How to manage the interaction:
Taking Eptoin 50 mg Injection 5 x 2 ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Coadministration of Eptoin 50 mg Injection 5 x 2 ml with Apremilast may reduce the blood levels of apremilast, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Eptoin 50 mg Injection 5 x 2 ml and Apremilast together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Eptoin 50 mg Injection 5 x 2 ml:
Using Eptoin 50 mg Injection 5 x 2 ml together with Isoniazid may increase the effects of Eptoin 50 mg Injection 5 x 2 ml, which may increase the risk of side effects.

How to manage the interaction:
Although taking Eptoin 50 mg Injection 5 x 2 ml and Isoniazid together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience jerky eye movements, slurred speech, loss of balance, shaking, muscle stiffness or weakness, nausea, vomiting, feeling dizzy, fainting, and slow or shallow breathing, consult a doctor immediately. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Side Effects of Eptoin 50 mg Injection 5 x 2 ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Eptoin 50 mg Injection 5 x 2 ml Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Eptoin 50 mg Injection 5 x 2 ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Eptoin 50 mg Injection 5 x 2 ml helps in controlling epileptic fits.

Eptoin 50 mg Injection 5 x 2 ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Eptoin 50 mg Injection 5 x 2 ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.

Eptoin 50 mg Injection 5 x 2 ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.

Eptoin 50 mg Injection 5 x 2 ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Eptoin 50 mg Injection 5 x 2 ml.

Drug-Drug Interactions Checker List

  • DELAVIRDINE
  • ASPIRIN
  • ACETAMINOPHEN
  • WARFARIN
  • CLOPIDOGREL
  • GABAPENTIN
  • PREGABALIN
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • LEVOTHYROXINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL

Special Advise

Consult your doctor immediately if you have suicidal thoughts such as harming or killing yourself.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Cardiac arrhythmia: Cardiac arrhythmia is a condition in which the heartbeats are abnormal or irregular. It occurs when the electrical signals in the heart do not work properly. Symptoms may include palpitations (a feeling as if the heart is pounding), chest pain, fainting, and dizziness.

Have a query?

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Eptoin 50 mg Injection 5 x 2 ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Eptoin 50 mg Injection 5 x 2 ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Eptoin 50 mg Injection 5 x 2 ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Eptoin 50 mg Injection 5 x 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Eptoin 50 mg Injection 5 x 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Eptoin 50 mg Injection 5 x 2 ml can be given to children if prescribed by the doctor.

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