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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ERLOTINIB-100MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Erlotero-100Mg Tablet

Erlotero-100Mg Tablet belongs to the group of medicine called ‘anti-cancer’ primarily used for lung and pancreatic cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain. Pancreatic cancer is an uncontrolled cancerous growth in the pancreas, usually in the cells that produce insulin.

Erlotero-100Mg Tablet contains 'Erlotinib' that belongs to the group of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it prevents the spread of cancerous cells.

Take Erlotero-100Mg Tablet as prescribed by your doctor. You are suggested to take Erlotero-100Mg Tablet as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side-effects such as abdominal pain, bone pain, breathlessness, constipation, cough, diarrhea, edema (swelling), fatigue, fever, infection, muscle pain, nausea, rash, stomatitis (inflammation of the mouth), vomiting, weight loss abnormal blood tests for the liver function. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Erlotero-100Mg Tablet for as long as your doctor has prescribed. Do not take Erlotero-100Mg Tablet if you are pregnant or planning for pregnancy and breastfeeding as Erlotero-100Mg Tablet causes serious congenital disabilities. Older adults are more sensitive to medicine so that they may adjust the dosage according to the condition. While taking Erlotero-100Mg Tablet , you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF). Regular blood tests are required to monitor liver function and blood cells in the blood while taking Erlotero-100Mg Tablet . Avoid consuming alcohol along with Erlotero-100Mg Tablet as it could lead to increased dizziness.

Uses of Erlotero-100Mg Tablet

Lung cancer, Pancreatic cancer

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Erlotero-100Mg Tablet is prescribed to the patients dealing with nonsmall cell lung cancer and pancreatic cancer. Cancer of this type tends to spread quickly in other parts of the body. Erlotero-100Mg Tablet travel through the bloodstream and effectively destroy cancerous cells of the lung, pancreas, and other body parts. Erlotero-100Mg Tablet contains Erlotinib is a 'tyrosine kinase inhibitor (TKI)' that stops the uncontrolled growth and spread of cancerous cells. It acts by blocking the abnormal protein's action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so Erlotero-100Mg Tablet targets cancerous cells and block the action of Tyrosine kinases enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Erlotero-100Mg Tablet stops the production, spread, and growth of cancerous cells in the body. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Erlotero-100Mg Tablet

  • ​​​​Stomach pain
  • Bone pain
  • Breathlessness
  • Constipation
  • Cough
  • Diarrhea
  • Loss of appetite
  • Edema (swelling)
  • Fatigue
  • Fever
  • Infection
  • Muscle pain
  • Nausea
  • Rash
  • Changes in vision
  • Partial hair loss (by strands, not typically in clumps)
  • Stomatitis (Inflammation of the mouth)
  • Weight loss
  • Abnormal blood tests for the liver function

Drug Warnings

Do not take Erlotero-100Mg Tablet if you are allergic to Erlotero-100Mg Tablet or any of its ingredients. While taking Erlotero-100Mg Tablet , you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF. Erlotero-100Mg Tablet can cause leg swelling and water retention or fluid overload (edema), so if you have unexpected rapid weight gain, please consult your doctor. Do not take Erlotero-100Mg Tablet if you are pregnant or planning to get pregnant and breastfeeding as it could harm the unborn baby. Use effective birth control measures while taking this medication and for at least 1 month after your last dose. Erlotero-100Mg Tablet is not recommended for children and adolescents. You are advised to stop smoking while taking Erlotero-100Mg Tablet as smoking could decrease this medication's effect. Erlotero-100Mg Tablet may make you more susceptible to infections, consult your doctor if you develop any signs of infections, fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.  Erlotero-100Mg Tablet may cause blurry vision and dizziness, so do not drive or operate any machinery which requires concentration. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking. 

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
ErlotinibRabeprazole
Critical

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
How does the drug interact with Erlotero-100Mg Tablet:
Omeprazole can make Erlotero-100Mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Omeprazole and Erlotero-100Mg Tablet together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ErlotinibRabeprazole
Critical
How does the drug interact with Erlotero-100Mg Tablet:
When used in combination with Erlotero-100Mg Tablet, Rabeprazole may prevent the absorption of Erlotero-100Mg Tablet into the circulation, which might make Erlotero-100Mg Tablet less effective in treating cancer.

How to manage the interaction:
Taking Rabeprazole with Erlotero-100Mg Tablet is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
ErlotinibDexlansoprazole
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Co-administration of Dexlansoprazole with Erlotero-100Mg Tablet may interfere with the absorption of Erlotero-100Mg Tablet making it less effective.

How to manage the interaction:
Taking Dexlansoprazole with Erlotero-100Mg Tablet can possibly lead to an interaction. Consult a doctor if you have any concerns, he/she may prescribe alternatives that do not interact. Do not discontinue the medication without consulting a doctor.
ErlotinibRifabutin
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Taking Rifabutin and Erlotero-100Mg Tablet may significantly reduce the blood levels of Erlotero-100Mg Tablet.

How to manage the interaction:
Co-administration of Erlotero-100Mg Tablet with Rifabutin can result in an interaction, but it can be taken if your doctor has advised it. If you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.
ErlotinibAtorvastatin
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Coadministration of Erlotero-100Mg Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlotero-100Mg Tablet with Atorvastatin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ErlotinibMitotane
Severe
How does the drug interact with Erlotero-100Mg Tablet:
When Erlotero-100Mg Tablet is taken with mitotane, it reduces the blood levels of Erlotero-100Mg Tablet.This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Erlotero-100Mg Tablet with Mitotane can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
ErlotinibPhenytoin
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Phenytoin may decrease the blood levels of Erlotero-100Mg Tablet, which may make Erlotero-100Mg Tablet less effective in treating your condition.

How to manage the interaction:
Although taking Phenytoin and Erlotero-100Mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ErlotinibTeriflunomide
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Taking Erlotero-100Mg Tablet with Teriflunomide can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Erlotero-100Mg Tablet with Teriflunomide together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ErlotinibEnzalutamide
Severe
How does the drug interact with Erlotero-100Mg Tablet:
Taking Enzalutamide with Erlotero-100Mg Tablet may decrease the blood levels of Erlotero-100Mg Tablet, which may make Erlotero-100Mg Tablet less effective.

How to manage the interaction:
Although taking Enzalutamide and Erlotero-100Mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
ErlotinibPrimidone
Severe
How does the drug interact with Erlotero-100Mg Tablet:
When Erlotero-100Mg Tablet is taken with primidone, it reduces the blood levels of Erlotero-100Mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Erlotero-100Mg Tablet with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ERLOTINIB-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ERLOTINIB-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can increase the absorption of Erlotero-100Mg Tablet which may lead to higher blood levels of Erlotero-100Mg Tablet and possibly increased side effects. Avoid or limit the consumption of Grapefruit juice or Grapefruit while taking Erlotero-100Mg Tablet as it can lead to increased risk or severity of side effects. However, if you notice any Burning, tingling, numbness or pain in the hands, arms, feet, or legs, cough or hoarseness, or severe diarrhea, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Diet & Lifestyle Advise

  • ​​​​​​Physical activity helps in strengthening muscles, reduce fatigue, aids in weight loss, and give strength. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and reduce stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fiber help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption. 

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Erlotero-100Mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Erlotero-100Mg Tablet contains Erlotinib, an anti-cancer medication that works by preventing the activity of a protein called epidermal growth factor receptor (EGFR) and hence induces cell death (apoptosis). As a result, the growth and spread of cancer cells in stopped or slowed down.

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing.

Erlotero-100Mg Tablet is safe to be taken by a diabetic person. However, take Erlotero-100Mg Tablet only after asking with a doctor as they may adjust the dosing according to the patient's condition.

In elderly patients, the risk of side effects is more if you are taking Erlotero-100Mg Tablet . For the patients who are elderly, dose adjustment might be required or your doctor might prescribe any other medication safe for the elderly.

Erlotero-100Mg Tablet can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

No, It is advised to maintain a gap between both the medicines, as use of antacids along with Erlotero-100Mg Tablet may affect the way the Erlotero-100Mg Tablet works. Consult your doctor for further information.

Erlotero-100Mg Tablet should be used with caution in patients using anticoagulants. Erlotero-100Mg Tablet may increase your tendency to bleed. Talk to your doctor, he will need to regularly monitor you with some blood tests.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • AMLODIPINE
  • METOPROLOL
  • NIFEDIPINE
  • QUINIDINE
  • ATORVASTATIN
  • FLUVASTATIN
  • PRAVASTATIN
  • ROSUVASTATIN
  • SIMVASTATIN
  • CYCLOSPORINE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • CIPROFLOXACIN
  • ITRACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • TRIAZOLAM
  • ALPRAZOLAM
  • ESTAZOLAM
  • PRIMIDONE
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • SAQUINAVIR
  • RITONAVIR
  • SILDENAFIL
  • OMEPRAZOLE
  • RANITIDINE

Special Advise

  • ​​​​​​Regular blood test is required to monitor liver function and blood cells in blood while taking Erlotero-100Mg Tablet .
  • While taking Erlotero-100Mg Tablet , you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF.
  • Always take it with food and a full glass of water to prevent nausea.
  • Erlotero-100Mg Tablet can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. 
  • Do not have immunizations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterward. 
  • Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Disease/Condition Glossary

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of NSCLC is a cough that does not go quickly followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is a type of tumor in the pancreas that usually begins in the juice's cells. It is a gland behind your stomach that produces juices that help break down food and the hormones that help control blood sugar levels.

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