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  3. Estradine Tablet 21's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Estradine Tablet

Estradine Tablet is a combined oral contraceptive used as a means of birth control in women who wish to prevent unwanted pregnancy. Additionally, it is also used in the treatment of irregular menstrual cycles and moderate to severe acne. A combined oral contraceptive is a birth-control pill, colloquially referred to as the pill, and it is used as a means of oral birth control by women.

Estradine Tablet is composed of Ethinyl estradiol and Dienogest. It is an ovulation inhibitor, which inhibits the release of potent eggs from the ovary, thereby preventing pregnancy. It also changes the cervical ambience, making cervical secretions thicker and hostile to any incoming sperm. Hence, it is a very potent contraceptive. In addition, the dienogest component inhibits gonadotropin (sex hormone) production and also suppresses the growth of uterine cells. Therefore, Estradine Tablet helps prevent pregnancy.

Estradine Tablet may be taken on an empty stomach, but it is better to take it after having food. In some cases, Estradine Tablet may cause certain common side effects such as nausea, breast soreness, headache and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

If you are allergic to any of its components, please inform the doctor before using Estradine Tablet . Keep the doctor informed if you are on treatment for any cardiovascular disease, mental health disorder, liver disease, gallbladder disease or breast/uterine/cervical cancer. Before taking Estradine Tablet , inform your doctor of your entire medical and surgical history. Please consult your doctor before taking Estradine Tablet during pregnancy or if you are breastfeeding.

Uses of Estradine Tablet

Contraception, Menorrhagia (heavy/prolonged bleeding), Acne.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Estradine Tablet is a combined oral contraceptive that contains two hormones, oestrogen (ethinyl estradiol) and progestin (dienogest). Estradine Tablet is used to prevent pregnancy by suppressing ovulation and changing the consistency of cervical secretions. In patients suffering from menorrhagia, Estradine Tablet reduces the intensity and duration of menstrual bleeding. Estradine Tablet reduces hair and skin greasiness, providing relief to blackheads/whiteheads and acne-prone skin. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Estradine Tablet should not be used in case of any known allergy to either of the components. Inform your doctor if you have/had mental health disorders, arterial or thrombotic disorders, cardiovascular health disorders, liver disease, gallbladder disease, history of breast/uterine/cervical cancer, hormone-sensitive cancer or if you smoke. Women with a history of angioedema should exercise caution while taking Estradine Tablet as it may worsen the angioedema. Avoid taking Estradine Tablet during pregnancy or breastfeeding. It is advisable not to consume alcohol with Estradine Tablet . Inform the doctor right away if you notice any dark urine, yellowing of the eyes/skin, severe mood changes, or sudden heavy bleeding. Women with a tendency for chloasma/melasma (skin condition commonly seen in middle-aged women) should avoid sun exposure after taking Estradine Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Estradine Tablet:
Taking Estradine Tablet with Tranexamic acid may increase the risk of blood clot formation.

How to manage the interaction:
Taking Estradine Tablet with Tranexamic acid is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Estradine Tablet:
When Efavirenz is taken with Estradine Tablet, it can lower the metabolism of Estradine Tablet and increase the risk or severity of side effects.

How to manage the interaction:
Taking Efavirenz with Estradine Tablet can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Estradine Tablet:
Taking ethinyl estradiol with griseofulvin may reduce blood levels and the effects of ethinyl estradiol.

How to manage the interaction:
Although taking Estradine Tablet and Griseofulvin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you use hormone replacement therapy (ethinyl estradiol) for menopause, inform a doctor if your symptoms are no longer controlled or if you deal with unusual bleeding. Do not stop using any medications without a doctor's advice.
EthinylestradiolFosphenytoin
Severe
How does the drug interact with Estradine Tablet:
When Fosphenytoin is taken with Estradine Tablet, Fosphenytoin may lower the blood levels and effects of Estradine Tablet.

How to manage the interaction:
There may be a possibility of interaction between Estradine Tablet and Fosphenytoin, but it can be taken if prescribed by a doctor. If you use hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer controlled or if you experience unusual bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estradine Tablet:
When taken together ethinyl estradiol may interfere with letrozole's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking Letrozole and Estradine Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estradine Tablet:
When Estradine Tablet is taken with phenobarbital, Estradine Tablet may become les effective.

How to manage the interaction:
Although taking phenobarbital and Estradine Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you use hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer controlled or if you experience unusual bleeding. Do not stop using any medications without talking to a doctor.
How does the drug interact with Estradine Tablet:
When coupled with Dabrafenib, the blood level of Estradine Tablet can be reduced.

How to manage the interaction:
There may be a possibility of interaction between Dabrafenib and Estradine Tablet, but it can be taken if prescribed by a doctor. If you are taking hormone replacement therapy for menopause, you should notify your doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Estradine Tablet:
Taking rifabutin with ethinyl estradiol it may significantly reduces the blood levels.

How to manage the interaction:
There may be a possibility of interaction between Estradine Tablet and Rifabutin, but it can be taken if prescribed by a doctor. If you use hormone replacement therapy for menopause, inform a doctor if experience any unusual symptoms or if you develop unusual bleeding. Do not stop using any medications without talking to a doctor.
How does the drug interact with Estradine Tablet:
Carfilzomib can cause serious blood clots and taking it with ethinyl estradiol may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Carfilzomib and Estradine Tablet, but it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, you should consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Estradine Tablet:
Phenytoin may lower ethinyl estradiol levels in the blood and its effects. You may be more likely to experience breakthrough bleeding and unexpected pregnancy if you use low-dose oral contraceptives.

How to manage the interaction:
Although taking Phenytoin and Estradine Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you are on hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer being controlled or if you are experiencing abnormal bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • As nausea and vomiting may occur with the use of Estradine Tablet , make sure to take it on light, small meals. 
  • After starting Estradine Tablet , use another alternative non-hormonal contraceptive for at least ten days.
  • Maintaining a healthy weight can go a long way in promoting healthy female reproductive health. Make sure you exercise for at least 30 minutes every day. However, do not engage in very strenuous physical exercise as this can worsen bleeding. 
  • Regularly working night shifts can affect hormone production. Try to avoid night shifts. 
  • Maintain good sexual hygiene and prevent any sexually transmitted diseases by practising only safe sex.
  • Limit your intake of caffeine and alcohol. 
  • Avoid smoking. 
  • Avoid grapefruit juice while taking Estradine Tablet as this may interact with Estradine Tablet and affect its absorption. 
  • Increase your intake of red vegetables, fruits, dry fruits, spinach, nuts and beans as these help in new blood formation. 
  • Keeping your skin hydrated by drinking enough water can also do wonders for the overall quality of your skin. 
  • Exfoliate your skin lightly but regularly. This helps wash away dry and dead cells, cleansing the skin.

Habit Forming

No

Therapeutic Class

CONTRACEPTIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Estradine Tablet works by suppressing ovulation and by changing cervical mucous thickness, thereby preventing pregnancy and acting as an effective birth control method.

It is not advisable to use Estradine Tablet for at least a minimum of 4 weeks after delivery. After 4weeks you can resume its use. Please consult your doctor for more information.

Estradine Tablet is not known to affect conception rates as it’s been found that women got pregnant pretty soon after discontinuing Estradine Tablet . Please consult your doctor for more information.

Estradine Tablet is not recommended or indicated in the treatment of any breast tumours or cancers.

It is considered as a missed dose if you vomit within 2 hours of taking Estradine Tablet . So, you should take another dose as soon as you feel better.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • FELBAMATE
  • TOPIRAMATE
  • ST JOHN'S WORT
  • RIFAMPICIN
  • RIFABUTIN
  • GRISEOFULVIN
  • NELFINAVIR
  • RITONAVIR

Special Advise

  • Do not skip tablets or delay intake by more than 12 hours. Try to catch up as early as possible in case of a missed dose. However, if the time for the second dose has come too close, revert to your original schedule. 
  • Chart your menstrual cycle and take Estradine Tablet on day 1 of your cycle, i.e. day 1 of your period. 
  • Use a condom or any non-hormonal contraceptive for the first ten days after starting Estradine Tablet .
  • Please inform the doctor immediately if you notice any breast lump, dark urine, yellowing of the skin, mood changes, headache, palpitations, severe fatigue or any alarming changes in vaginal bleeding. 
  • Call for the doctor right away in case of any stroke symptoms such as breathlessness, confusion, dizziness, left arm pain, jaw pain or sudden vision changes or any pulmonary embolism symptoms such as cough, leg pain, warmth, pain in calf etc.

Disease/Condition Glossary

Oral Contraception: Oral contraception is birth control taken by mouth by women to prevent pregnancy. It is commonly referred to as the pill. Oral contraceptives contain hormonal preparations of female sex hormones for birth control. 

Menorrhagia: Severe loss of blood during a period lasting more than seven days is called menorrhagia. It is a form of dysfunctional uterine bleeding. Common signs and symptoms include heavy bleeding and large blood clots.

Acne: Acne is a skin condition in which pores get blocked or clogged, leading to the appearance of whiteheads, blackheads, pimples and greasy skin. It is caused by a bacterium called Propionibacterium acnes.

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