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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

ESTRAMUSTINE-140MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Estramin 140mg Capsule

Estramin 140mg Capsule is an antineoplastic medicine used in the treatment of prostate cancer. It is used to treat metastatic or progressive prostate cancer (a condition where cancer does not get cured) in men. Prostate cancer is a condition that occurs when the number of prostate gland cells increases abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Estramin 140mg Capsule contains Estramustine, which belongs to the class of antimicrotubule agents. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells.

Estramin 140mg Capsule may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, hot flushes, nausea, vomiting, thirst, flatulence, edema, and GI bleeding. These side effects usually disappear without any medical attention. However, if these side effects persist or worsen, consult your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or post meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Estramin 140mg Capsule should be avoided if you are allergic to estradiol, nitrogen mustard or any component present in this medicine. Inform your doctor about medications you use to avoid interactions. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, hypocalcemia, thrombophlebitis, fluid retention, coronary artery disease, diabetes, gynecomastia, or impotence before taking Estramin 140mg Capsule. Estramin 140mg Capsule is not recommended for use in women and children as this medicine is recommended for men. Estramin 140mg Capsule is known to cause thrombosis, fatal and nonfatal myocardial infarction, glucose intolerance and elevated blood pressure in some patients. Hence, close monitoring should be done during the treatment. 

Uses of Estramin 140mg Capsule

Metastatic Prostate Cancer.

Directions for Use

Estramin 140mg Capsule should be taken on an empty stomach at least two hours before or after a meal. It is advised not to take more than the recommended dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew, crush or break the medicine.

Medicinal Benefits

Estramin 140mg Capsule contains Estramustine, which belongs to the class of antimicrotubule agents. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Estramin 140mg Capsule should be avoided if you are allergic to it or either estradiol or nitrogen mustard. Keep a note of all your ongoing medications to avoid interactions. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, hypocalcemia, thrombophlebitis, fluid retention, coronary artery disease, diabetes, Gynecomastia, or impotence before taking Estramin 140mg Capsule. Estramin 140mg Capsule is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Estramin 140mg Capsule is known to cause thrombosis, fatal and nonfatal myocardial infarction, glucose intolerance and elevated blood pressure in some patients. Hence, close monitoring should be done during the entire treatment course. Do not take Estramin 140mg Capsule with milk or any other dairy products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Estramin 140mg Capsule:
Co-administration of Exemestane with Estramin 140mg Capsule may interfere with exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Exemestane and Estramin 140mg Capsule, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Estramin 140mg Capsule:
Co-administration of Estramin 140mg Capsule with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Estramin 140mg Capsule with Tranexamic acid possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Estramin 140mg Capsule:
when taken together letrozole's function could be blocked by Estramin 140mg Capsule, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking Letrozole and Estramin 140mg Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Estramin 140mg Capsule Substitute

Substitutes safety advice
  • Xtrant Capsule 100's

    by Others

    63.74per tablet
  • ESTRAM 140MG CAPSULE

    by Others

    19.32per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Estramin 140mg Capsule contains Estramustine, which belongs to the class of antimicrotubule agents. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells.

No, do not stop taking Estramin 140mg Capsule without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

Drug-Drug Interactions Checker List

  • MAGNESIUM HYDROXIDE
  • ALUMINIUM HYDROXIDE
  • KETOCONAZOLE
  • ITRACONAZOLE

Special Advise

  • Estramin 140mg Capsule is not recommended for use in patients suffering from severe kidney disease.
  • Regular checkups on your calcium, potassium, blood sugar, and blood pressure levels are advised.

Disease/Condition Glossary

Prostate cancer: The prostate gland is a small walnut-sized gland present under the bladder which is responsible for the production of seminal fluid. Prostate cancer is a carcinogenic condition that occurs when the prostate gland cells increase out of control. The main cause of this condition is unknown. However, a few underlying reasons that increase the risk for this condition include age, family history, ethnic group, genetic factors, obesity, etc.

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