ETHYOL 500MG INJECTION

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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MRP ₹12000

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Whats That

About ETHYOL 500MG INJECTION

ETHYOL 500MG INJECTION belongs to the class of cytoprotective agents. It is used in reducing cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer. It is also used for the reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer.

ETHYOL 500MG INJECTION contains Amifostine, which belongs to the class of protective agents. It works by protecting the kidneys in patients undergoing chemotherapy and radiation therapy.

ETHYOL 500MG INJECTION may cause certain side effects such as nausea, vomiting, pain at the site of injection, and injection site reactions. Inform your doctor if any of these side effects persist for longer. ETHYOL 500MG INJECTION will be administered by your physician in the hospital. Do not self-administer.

Avoid receiving ETHYOL 500MG INJECTION and inform your doctor if you are allergic to it or any other components of it. Before taking ETHYOL 500MG INJECTION, tell your doctor if you have/had liver or kidney disease, cardiac problems, skin disorders, and low calcium levels. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this ETHYOL 500MG INJECTION.

Uses of ETHYOL 500MG INJECTION

Ovarian Cancer.

Directions for Use

ETHYOL 500MG INJECTION will be administered by a trained healthcare professional in the hospital setting. Hence, do not self-administer. Your doctor will decide the dose and duration of the treatment based on the severity and type of cancer.

Medicinal Benefits

ETHYOL 500MG INJECTION contains Amifostine, which is used in protecting kidneys from renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer. It is a cytotoxic medicine that detoxifies the reactive metabolites of platinum and alkylating agents.

Storage

Keep ETHYOL 500MG INJECTION out of the sight and reach of children.

Side effects of Ethyol 500mg Injection

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Low Blood Pressure

Managing Low Blood Pressure Triggered by Medication: Expert Advice:

If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
Take regular breaks to sit or lie down if you need to stand for long periods.
When lying down, elevate your head with extra pillows to help improve blood flow.
Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Low Calcium Levels In Blood

Managing Medication-Triggered Hypocalcemia (Calcium deficiency or Low Calcium Levels In Blood): A Step-by-Step Guide:

Consult Your Doctor: If you experience symptoms such as muscle cramps, tingling, numbness, weakness, or spasms, which may indicate low calcium levels (hypocalcemia), consult your doctor to determine if your medication is the cause.
Your doctor will assess your medication regimen and adjust it if necessary to minimize the risk of hypocalcemia.
Your doctor may order blood tests to check your calcium levels and monitor for any changes.
To manage hypocalcemia, your doctor recommends dietary and lifestyle modifications. This may include increasing your intake of calcium-rich foods to support bone health and calcium levels. If necessary, your doctor may also prescribe calcium and vitamin D supplements to help stabilize your calcium levels.
If your condition does not improve or worsens, consult your doctor immediately for further evaluation and treatment.

Drug Warnings

To treat your condition effectually, continue receiving ETHYOL 500MG INJECTION for the period that your doctor has prescribed. ETHYOL 500MG INJECTION may cause severe cutaneous reactions, hypotension, cardiovascular problems, nausea, vomiting, and hypocalcemia. Therefore, caution should be exercised if you have/had liver or kidney disease, heart problems, and skin disorders while receiving ETHYOL 500MG INJECTION. This medicine may also cause severe hypersensitivity reactions. Hence, careful monitoring is recommended and discontinue the treatment if any severe allergic reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
Eat food rich in antioxidants such as berries, spinach, etc.
Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
Avoid smoking and alcohol consumption.
Maintain a healthy weight.

Side Effects of ETHYOL 500MG INJECTION

Nausea
Vomiting
Pain at the site of injection
Allergic reactions
Injection site reactions

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does ETHYOL 500MG INJECTION work?

ETHYOL 500MG INJECTION contains Amifostine, which works by protecting the kidneys in patients undergoing chemotherapy and radiation therapy.

Drug-Drug Interactions Checker List

METOPROLOL
AMLODIPINE
ETELCALCETIDE
CILNIDIPINE
SPIRONOLACTONE

Special Advise

Your doctor may suggest periodic blood test to monitor the function of the kidney and calcium levels due to the use of ETHYOL 500MG INJECTION.
Using contraceptive pills while using ETHYOL 500MG INJECTION to prevent pregnancy is advised.
Regular blood pressure monitoring is recommended during the treatment course to check for any changes in cardiovascular events.

Disease/Condition Glossary

Ovarian cancer: It is a common type of cancer that occurs when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body (metastasis). This is called metastatic ovarian cancer. Symptoms may include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.