Evalon Cream 15 gm belongs to a group of medicines called hormone replacement therapy used to relieve menopausal symptoms in the vagina, such as vaginal atrophy (vaginal dryness or irritation). It is used before/after vaginal surgery to help wound healing. Vaginal atrophy occurs due to a drop in the levels of oestrogen that naturally happens after menopause.

Evalon Cream 15 gm contains ‘estriol’, which works by replacing the oestrogen that is normally produced by the ovaries, thereby helping provide relief from discomfort, dryness or irritation in the vagina.

In some cases, you may experience side effects such as itching, irritation of the skin around the vagina, swollen, tender, or painful breasts, headache, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Avoid using Evalon Cream 15 gm if you are pregnant, planning for pregnancy or breastfeeding. Stop using Evalon Cream 15 gm and consult a doctor if you notice jaundice, a large rise in blood pressure, migraine, if you become pregnant or if you notice any signs of a blood clot such as sudden chest pain, difficulty breathing, painful swelling and redness of the legs. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Evalon Cream 15 gm belongs to a group of medicines called hormone replacement therapy used to relieve menopausal symptoms in the vagina, such as vaginal atrophy (vaginal dryness or irritation). It is used before/after vaginal surgery to help wound healing. Evalon Cream 15 gm contains ‘estriol’, which replaces the oestrogen normally produced by the ovaries, helping relieve discomfort in the vagina, vaginal dryness or irritation.

• Irritation or itching of the skin around the vagina
• Increased vaginal discharge, bleeding, or spotting
• Swollen, tender, or painful breasts
• Headache
• Nausea 
• Flu-like symptoms

Do not use Evalon Cream 15 gm if you are allergic to any of its contents; if you have/had breast cancer, endometrial cancer, unexplained vaginal bleeding, endometrial hyperplasia (excessive thickening of the womb lining), thrombosis (blood clot in the vein), blood clotting disorder, heart attack, stroke, angina, or porphyria. Inform your doctor if you have fibroids inside the womb, endometriosis (growth of the womb lining outside the womb), risk of developing blood cancer or oestrogen-sensitive cancer, high blood pressure, liver disorder, gall stones, diabetes, migraines, immune system problems, blood clotting problems, asthma, epilepsy, otosclerosis (an inherited disorder that affects hearing), fluid retention due to kidney/cardiac problems or hepatitis C. 

Drug-Drug Interactions: Evalon Cream 15 gm may have interaction with anti-viral (ombitasvir, paritaprevir, dasabuvir, nevirapine, efavirenz, ritonavir, nelfinavir), anti-fungal (griseofulvin), anti-convulsant (barbiturates, hydantoins, carbamazepine), skeletal muscle relaxant (succinylcholine), xanthine (theophylline), antibiotic (troleandomycin), and corticosteroids. Inform your doctor if you are taking St. John’s wort (a herbal supplement to treat depression).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have breast cancer, endometrial cancer, unexplained vaginal bleeding, endometrial hyperplasia (excessive thickening of the womb lining), thrombosis, blood clotting disorder, heart attack, stroke, angina, or porphyria.

• OMBITASVIR
• PARITAPREVIR
• DASABUVIR
• NEVIRAPINE
• EFAVIRENZ
• RITONAVIR
• NELFINAVIR
• GRISEOFULVIN
• CARBAMAZEPINE
• SUCCINYLCHOLINE
• THEOPHYLLINE+ETOFYLLINE NICOTINATE
• TROLEANDOMYCIN

• Include foods such as soybeans, flax seeds, and soy products in the diet.
• Maintain a healthy weight by exercising regularly. Also, avoid exercising too much. Do it moderately.
• Avoid douching or using hygiene products containing fragrances, as they might further irritate the vagina.
• Drink plenty of water to stay hydrated. Try to limit alcohol and caffeine.
• Try to choose personnel care items that are pH balanced.

• Regular breast screening and regular check-ups whilst using Evalon Cream 15 gm are advised.
• Inform your doctor that you are using Evalon Cream 15 gm if you are due to have any surgery. Your doctor might advise you to stop using Evalon Cream 15 gm 4-6 weeks prior to the surgery to reduce the risk of a blood clot. Your doctor will decide when to start Evalon Cream 15 gm again.

Vaginal atrophy: When women get older, the ovaries gradually produce less oestrogen; this happens at menopause or if the ovaries are removed before menopause. Vaginal atrophy occurs due to a drop in the levels of oestrogen that naturally happens after menopause. It is a condition in which the vaginal lining becomes thinner and drier, leading to itching, burning sensation, pain during sex, dryness, and itching in the vagina.