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  3. Evergraf 0.5 Tablet 10's

Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Evergraf 0.5 Tablet 10's, Pack of 10 TabletS
Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Whats That

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Composition :

EVEROLIMUS-0.5MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Evergraf 0.5 Tablet

Evergraf 0.5 Tablet belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

Evergraf 0.5 Tablet contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Evergraf 0.5 Tablet as prescribed by your doctor. You are advised to take Evergraf 0.5 Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Evergraf 0.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking Evergraf 0.5 Tablet for as long as your doctor has prescribed. If you are known to be allergic to Evergraf 0.5 Tablet or any other medicines, please tell your doctor. Do not take Evergraf 0.5 Tablet if you are pregnant or planning for pregnancy as Evergraf 0.5 Tablet may harm the unborn baby. Evergraf 0.5 Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Evergraf 0.5 Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Evergraf 0.5 Tablet

Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

Take Evergraf 0.5 Tablet with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Evergraf 0.5 Tablet is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Evergraf 0.5 Tablet travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Storage

Store in a cool and dry place away from sunlight
Side effects of Evergraf 0.5 Tablet
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.

Drug Warnings

If you are known to be allergic to Evergraf 0.5 Tablet or any other medicines, please tell your doctor. Evergraf 0.5 Tablet should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take Evergraf 0.5 Tablet if you have recent surgery, infection and hepatitis B. Evergraf 0.5 Tablet may weaken your immune system, inform your doctor before taking Evergraf 0.5 Tablet . Evergraf 0.5 Tablet may also impair your kidney function. Therefore, monitor your kidney function regularly while taking Evergraf 0.5 Tablet . Evergraf 0.5 Tablet may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your Evergraf 0.5 Tablet . Evergraf 0.5 Tablet may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take Evergraf 0.5 Tablet if you are pregnant or planning for pregnancy as Evergraf 0.5 Tablet may harm the unborn baby. Evergraf 0.5 Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Evergraf 0.5 Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusLeflunomide
Severe
EverolimusNaproxen
Severe

Drug-Drug Interactions

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EverolimusLeflunomide
Severe
How does the drug interact with Evergraf 0.5 Tablet:
When Evergraf 0.5 Tablet is used with leflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Leflunomide and Evergraf 0.5 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusNaproxen
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Coadministration of Naproxen and Evergraf 0.5 Tablet can increase the risk or severity of kidney problems

How to manage the interaction:
Taking Naproxen and Evergraf 0.5 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
EverolimusOxaprozin
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Evergraf 0.5 Tablet can cause kidney issues, and taking it with other medications that can harm the kidney, such as oxaprozin, can enhance the risk.

How to manage the interaction:
Although taking Evergraf 0.5 Tablet and Oxaprozin together can cause an interaction, it can be taken if your doctor has suggested it. However, If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult your doctor.
EverolimusSaquinavir
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Taking Evergraf 0.5 Tablet with saquinavir can considerably raise blood levels of Evergraf 0.5 Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Taking Evergraf 0.5 Tablet with Saquinavir together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusIbuprofen
Severe
How does the drug interact with Evergraf 0.5 Tablet:
The use of Evergraf 0.5 Tablet and Ibuprofen can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Evergraf 0.5 Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
EverolimusAmikacin
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Coadministration of Amikacin and Evergraf 0.5 Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking amikacin and Evergraf 0.5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, increased or decreased urination, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.
EverolimusMethotrexate
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Coadministration of Evergraf 0.5 Tablet with Methotrexate can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Evergraf 0.5 Tablet with Methotrexate together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusEfavirenz
Severe
How does the drug interact with Evergraf 0.5 Tablet:
When Evergraf 0.5 Tablet is taken with Efavirenz, the effect of Evergraf 0.5 Tablet is reduced.

How to manage the interaction:
Co-administration of Evergraf 0.5 Tablet with Efavirenz can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
EverolimusLetermovir
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Taking Evergraf 0.5 Tablet with letermovir can considerably raise blood levels of Evergraf 0.5 Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although taking Evergraf 0.5 Tablet and Letermovir together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without a doctor's advice.
EverolimusPhenytoin
Severe
How does the drug interact with Evergraf 0.5 Tablet:
Coadministration of Phenytoin and Evergraf 0.5 Tablet may decrease the blood levels of Evergraf 0.5 Tablet, which may make Evergraf 0.5 Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Evergraf 0.5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-0.5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Evergraf 0.5 Tablet with grapefruit juice can raise blood levels and enhance the effects of Evergraf 0.5 Tablet. Since the co-administration of Evergraf 0.5 Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Evergraf 0.5 Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Evergraf 0.5 Tablet Substitute

Substitutes safety advice

  • Certican 0.5 Tablet 10's

    by Others

    ₹200.20per tablet

  • Advacan 0.5 mg Tablet 10's

    by Others

    ₹98.55per tablet

  • Lanolimus 0.5 mg Tablet 10's

    by Others

    ₹66.51per tablet

  • Everotas 0.5 mg Tablet 10's

    by Others

    ₹87.39per tablet

  • Ever-Rite 0.5 Tablet 10's

    by Others

    ₹74.25per tablet

Product Substitutes

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Evergraf 0.5 Tablet is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.

There is no specific duration of treatment with Evergraf 0.5 Tablet . Evergraf 0.5 Tablet is continued till benefit is seen or undesirable toxicity or side effects occur.

You should prevent grapefruit or grapefruit juice while taking Evergraf 0.5 Tablet . This is because taking them together may rise the levels of Evergraf 0.5 Tablet in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.

Evergraf 0.5 Tablet can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.

It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • RITONAVIR
  • EFAVIRENZ
  • RAMIPRIL
  • VERAPAMIL
  • DILTIAZEM
  • DRONEDARONE
  • IMATINIB
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • FLUCONAZOLE

Special Advise

  • Evergraf 0.5 Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Evergraf 0.5 Tablet .
  • Do not have immunizations/vaccinations without a doctor's advice.
  • Avoid contact with people who have recently received live vaccines.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells that are stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumor cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. 

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of lung cancer is a cough that does not go easily followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices. Juices are produced by the pancreas ( a gland present behind your stomach) help in the breakdown of food and hormones which help in controlling blood sugar levels.

Kidney cancer: Kidneys are the organs on either side of your backbone directly above your waist. The tubes present inside clean and filter your blood, taking out waste foods and making urine. Kidney cancer produces in the lining of tiny tubes inside your kidneys.

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