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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Exena-S 25/5 Tablet 10's

Exena-S 25/5 Tablet 10's is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control.
 
Exena-S 25/5 Tablet 10's contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Exena-S 25/5 Tablet 10's helps in treating overactive bladder.
 
You are advised to take Exena-S 25/5 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Exena-S 25/5 Tablet 10's is not recommended for children as safety and efficacy have not been established. Exena-S 25/5 Tablet 10's may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption along with Exena-S 25/5 Tablet 10's as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Exena-S 25/5 Tablet 10's to rule out any side effects/interactions.

Uses of Exena-S 25/5 Tablet 10's

Overactive bladder syndrome

Directions for Use

Swallow Exena-S 25/5 Tablet 10's as a whole with water; do not chew or break it.

Medicinal Benefits

Exena-S 25/5 Tablet 10's is a combination of two drugs, namely: Solifenacin and Mirabegron. Exena-S 25/5 Tablet 10's is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, dysuria (painful or difficult urination). Solifenacin is an anti-cholinergic that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron is a beta-3 adrenergic agonist which relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Exena-S 25/5 Tablet 10's helps in treating an overactive bladder.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Exena-S 25/5 Tablet 10's

  • Constipation
  • Headache 
  • Dry mouth
  • Blurred vision
  • Vomiting
  • High blood pressure
  • Urinary tract infection

Drug Warnings

Do not take Exena-S 25/5 Tablet 10's if you are allergic to any of its contents. Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Exena-S 25/5 Tablet 10's is not recommended for children. Exena-S 25/5 Tablet 10's may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption with Exena-S 25/5 Tablet 10's as it could lead to increased dizziness. 

Drug-Drug Interactions

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SolifenacinPotassium chloride
Critical
SolifenacinMesoridazine
Critical

Drug-Drug Interactions

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SolifenacinPotassium chloride
Critical
How does the drug interact with Exena-S 25/5 Tablet:
Taking Exena-S 25/5 Tablet and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Exena-S 25/5 Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
SolifenacinMesoridazine
Critical
How does the drug interact with Exena-S 25/5 Tablet:
Using Mesoridazine together with Exena-S 25/5 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Exena-S 25/5 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
SolifenacinItraconazole
Critical
How does the drug interact with Exena-S 25/5 Tablet:
The blood levels and effects of Exena-S 25/5 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Exena-S 25/5 Tablet and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
MirabegronEliglustat
Critical
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Eliglustat and Exena-S 25/5 Tablet can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Exena-S 25/5 Tablet with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
SolifenacinProcainamide
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Procainamide with Exena-S 25/5 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Procainamide with Exena-S 25/5 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
SolifenacinFosamprenavir
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Exena-S 25/5 Tablet with Fosamprenavir may significantly increase the blood levels of Exena-S 25/5 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Exena-S 25/5 Tablet and Fosamprenavir, but it can be taken if prescribed by a doctor. If you experience drowsiness, dizziness, irregular heartbeat, blurry vision, difficulty urinating, dry mouth, headache, gastrointestinal upset, or constipation, consult your doctor immediately. Do not stop using any medications without talking to a doctor.
SolifenacinCabozantinib
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Exena-S 25/5 Tablet with Cabozantinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Exena-S 25/5 Tablet and Cabozantinib, but it can be taken if prescribed by a doctor. If you experience drowsiness, dizziness, irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
SolifenacinPosaconazole
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Exena-S 25/5 Tablet with Posaconazole may significantly increase the blood levels of Exena-S 25/5 Tablet.

How to manage the interaction:
Although using Posaconazole and Exena-S 25/5 Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience drowsiness, irregular heartbeat, blurred vision, difficulty in urinating, dry mouth, headache, or constipation. Do not stop taking any medications without consulting a doctor.
SolifenacinAmprenavir
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Exena-S 25/5 Tablet with Amprenavir may significantly increase the blood levels of Exena-S 25/5 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Exena-S 25/5 Tablet and Amprenavir, but it can be taken if prescribed by a doctor. If you experience drowsiness, dizziness, irregular heartbeat, blurry vision, difficulty urinating, dry mouth, headache, gastrointestinal upset, or constipation. Do not stop using any medications without talking to a doctor.
SolifenacinMethadone
Severe
How does the drug interact with Exena-S 25/5 Tablet:
Coadministration of Methadone with Exena-S 25/5 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Methadone with Exena-S 25/5 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Quit smoking.
  • Take 6-8glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Exena-S 25/5 Tablet 10's Substitute

Substitutes safety advice
  • Mirago S 25 Tablet 10's

    by Others

    40.50per tablet
  • Mirbeg S 25 Tablet 10's

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    40.77per tablet
  • Mirabig-S 25 Tablet 10's

    by Others

    39.96per tablet
  • Bladmir-S 25 Tablet 10's

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    40.46per tablet
  • Megatas-S 25 Tablet 10's

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    42.48per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • METOPROLOL
  • ACETAMINOPHEN
  • ALBUTEROL

Disease/Condition Glossary

Overactive bladder (OAB): Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control. The contraction or tightening of bladder muscles causes bladder spasms. Continuous contractions may cause an urge to urinate. Overactive bladder is characterised by involuntary leakage of urine, excessive urination, and urgent need to urinate. The common causes of bladder spasms are urinary tract infections, drinking too much caffeine or alcohol, diabetes, constipation, impaired kidney function, bladder stones, enlarged prostate, or neurological disorders. Symptoms of overactive bladder include urinating more than 8 times a day and more than 2 times at night, strong and sudden need to urinate, leakage of urine, and loss of bladder control.

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