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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

FEBUXOSTAT-40MG

Manufacturer/Marketer :

S N Medi Health Care

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Febuxostat Capsule

Febuxostat Capsule belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used to prevent severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. Febuxostat Capsule prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

Febuxostat Capsule contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Febuxostat Capsule is used to prevent gout attacks or flares.

Your doctor will advise you on how often you take off the Febuxostat Capsule based on your medical condition. The common side effects of Febuxostat Capsule nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Most of these side effects of Febuxostat Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking a Febuxostat Capsule of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to Febuxostat Capsule or any other medicines, have a heart problem (Febuxostat Capsule may cause heart problems that can lead to heart attack), or have kidney/liver disease. Some people experience more gout flare-ups when you start taking Febuxostat Capsule . You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start Febuxostat Capsule . The safety and effectiveness of children under 18 years of age have not been established, so Febuxostat Capsule should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Febuxostat Capsule .

Uses of Febuxostat Capsule

Treatment of severe gout, prevention of gout attacks

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Febuxostat Capsule is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Febuxostat Capsule is used to prevent gout attacks or flares.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

You should avoid taking Febuxostat Capsule if you are allergic to Febuxostat Capsule , or have heart-related problems, as it increases the risk of a heart attack. It should be used cautiously in patients with kidney problems and blood disorders. Caution is required before taking Febuxostat Capsule if you are pregnant, planning to become pregnant, or already a breastfeeding mother. The safety and effectiveness of children under 18 years of age have not been established, so Febuxostat Capsule should not be given to them.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Febuxostat Capsule Capsule:
Taking azathioprine and Febuxostat Capsule together can increase the blood levels of azathioprine

How to manage the interaction:
Taking Azathioprine with Febuxostat Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Mercaptopurine with Febuxostat Capsule can increase the blood levels of mercaptopurine.

How to manage the interaction:
Taking Mercaptopurine with Febuxostat Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FebuxostatLomitapide
Severe
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with lomitapide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Lomitapide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with ketoconazole can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule with Leflunomide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Teriflunomide with Febuxostat Capsule can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat Capsule and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
FebuxostatMipomersen
Severe
How does the drug interact with Febuxostat Capsule Capsule:
Coadministration of Febuxostat Capsule with Mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Febuxostat Capsule with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic movements like walking on a treadmill and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Avoid a high purine-rich diet, including organ meats (kidneys, liver, and sweetbreads) and oily fish (sardines, anchovies, and herring).
  • Limit meat in favour of plant-based proteins like beans and legumes.
  • Eat complex carbohydrates, such as whole-grain bread, fruits, and vegetables, rather than sugary sweets and refined carbohydrates like white bread.
  • Avoid drinking beer and alcoholic beverages and drink plenty of water or other nonalcoholic beverages.

Habit Forming

No

Therapeutic Class

ANTI- GOUT MEDICATIONS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Febuxostat Capsule is a class of antigout drugs called xanthine oxidase inhibitors. It works by decreasing a high amount of uric acid to the normal level that is made in the body. Febuxostat Capsule is used to prevent gout attacks but not to treat them once they occur.

No, Do not discontinue Febuxostat Capsule without consulting your doctor. To treat your condition effectively, continue taking Febuxostat Capsule for as long as prescribed. If you stop taking Febuxostat Capsule , your uric acid levels will likely remain high and continue to cause gout symptoms.

Febuxostat Capsule is not recommended if you have heart disease; taking Febuxostat Capsule may cause serious heart problems, which can be life-threatening in some cases. So, please consult your doctor before taking the Febuxostat Capsule .

Do not drive or operate machinery if you experience dizziness or drowsiness while using Febuxostat Capsule .

The dose and duration of Febuxostat Capsule depend upon your medical condition. It may take several months before Febuxostat Capsule begins to prevent gout attacks. Do not stop taking Febuxostat Capsule without the advice of your doctor even if you feel better.

It is best taken in the morning. You can take Febuxostat Capsule with or without food. Keep taking Febuxostat Capsule every day, to prevent gout attacks.

Drug-Drug Interactions Checker List

  • MERCAPTOPURINE
  • METHOTREXATE
  • AZATHIOPRINE
  • THEOPHYLLINE
  • ROSIGLITAZONE

Special Advise

  • Please consult your doctor and check your levels of uric acid two weeks after starting Febuxostat Capsule . Your goal is a uric acid level in your blood that is less than 6 mg/dL.

Disease/Condition Glossary

Gout: Gout is a type of arthritis called 'gouty arthritis'. It is caused by a build-up of a naturally occurring chemical (uric acid) in your body (hyperuricemia). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation. The general signs and symptoms of gout include sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, mostly in the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain, often waking you up in the middle of the night with the sensation that your big toe is on fire.

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