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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Femoston 2/10 Combipack Tablet 28's

Femoston 2/10 Combipack Tablet 28's is a hormone replacement therapy (HRT) used to treat postmenopausal symptoms and prevent osteoporosis (weak and brittle bones) caused by menopause in women. Post-menopause is a condition in which women have not had a period for 12 months or more. During menopause, estrogen levels decrease, leading to hot flushes (feeling of heat over the face, neck, and chest). Women with menopause are at risk of developing osteoporosis (thinning of bones). Femoston 2/10 Combipack Tablet 28's can be used to prevent osteoporosis after menopause. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density which is common in post-menopausal women. 

Femoston 2/10 Combipack Tablet 28's contains two female hormones, Estradiol and Dydrogesterone. Estradiol works by replacing the falling levels of estrogen in the body and thus helps to reduce menopause symptoms. Dydrogesterone works by reducing the overgrowth of the womb lining. Together, Femoston 2/10 Combipack Tablet 28's helps treat postmenopausal symptoms and osteoporosis.

Femoston 2/10 Combipack Tablet 28's should be taken as advised by your doctor. The dose of medicine and duration of treatment will be decided by the doctor based on your medical condition. Femoston 2/10 Combipack Tablet 28's may cause certain side effects such as stomach pain, headache, breast pain or tenderness and back pain. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor. 

Femoston 2/10 Combipack Tablet 28's should be avoided if you are allergic to it or if you have a history of breast cancer, endometrial cancer (cancer of the lining of the womb), unexplained vaginal bleeding, untreated endometrial hyperplasia (thickening of the womb lining), blood clotting disorder, heart attack or angina (chest pain), inherited porphyria (a blood disorder) or liver disease. It is not recommended for use in pregnant and breastfeeding women. Stop taking Femoston 2/10 Combipack Tablet 28's and consult your doctor immediately if you develop jaundice (yellowing of the skin and eyes), high blood pressure and migraine-like headache, become pregnant or notice signs of a blood clot such as redness, swelling and pain in the legs, sudden chest pain or difficulty in breathing. Inform your doctor if you have any intolerance to sugar.

Uses of Femoston 2/10 Combipack Tablet 28's

Postmenopausal symptoms and osteoporosis after menopause

Directions for Use

Your doctor determines the dose of this medicine. Swallow it as a whole with a glass of water. Do not crush, chew or break it. Take this medication at a fixed time every day for better results.

Medicinal Benefits

Femoston 2/10 Combipack Tablet 28's contains Estradiol and Dydrogesterone used to treat postmenopausal symptoms and prevent osteoporosis (weak and brittle bones) caused by menopause in women. Estradiol restores the falling levels of estrogen in the body and thus helps to reduce menopause symptoms. Dydrogesterone decreases the overgrowth of the womb lining. Also, Femoston 2/10 Combipack Tablet 28's is used as prophylaxis in preventing osteoporosis in postmenopausal women and prevents bone loss and fractures.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Femoston 2/10 Combipack Tablet 28's

  • Stomach pain
  • Headache
  • Breast pain or tenderness
  • Back pain
  • Changes in your menstrual periods
  • Nausea

Drug Warnings

Before starting treatment with Femoston 2/10 Combipack Tablet 28's, inform your doctor if you are allergic to it. Avoid taking Femoston 2/10 Combipack Tablet 28's if you are pregnant or breastfeeding. Femoston 2/10 Combipack Tablet 28's is not recommended for children. If you have premature menopause, inform your doctor before taking Femoston 2/10 Combipack Tablet 28's so that the risks and benefits may be compared. Avoid taking Femoston 2/10 Combipack Tablet 28's if you have recently had a stroke, heart attack or angina (chest pain), liver disease and untreated endometrial hyperplasia (thickening of the womb lining). If you have very high levels of fat (triglycerides) in your blood, inform your doctor before taking Femoston 2/10 Combipack Tablet 28's. You are recommended to avoid alcohol consumption with Femoston 2/10 Combipack Tablet 28's as it may increase the risk of breast cancer. If you experience sudden chest pain, difficulty breathing, or painful swelling and redness of your legs, stop taking Femoston 2/10 Combipack Tablet 28's and consult a doctor immediately, as these might be signs of a blood clot. Long-term use and high dosages of this medication may raise your risk of heart attack, stroke, blood clots, breast cancer, or uterine cancer. Hence discuss this risk with your doctor before taking Femoston 2/10 Combipack Tablet 28's.

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolDantrolene
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Femoston 2/10 Combipack Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Femoston 2/10 Combipack Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolDantrolene
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
The usage of Femoston 2/10 Combipack Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Femoston 2/10 Combipack Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolLetrozole
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Letrozole may have a negative effect when used with Femoston 2/10 Combipack Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Femoston 2/10 Combipack Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolAnastrozole
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Femoston 2/10 Combipack Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Femoston 2/10 Combipack Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Femoston 2/10 Combipack Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Femoston 2/10 Combipack Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolClindamycin
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
When taken in combination, clindamycin can lower the amount or action of Femoston 2/10 Combipack Tablet.

How to manage the interaction:
Co-administration of Femoston 2/10 Combipack Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolThalidomide
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Taking thalidomide together with Femoston 2/10 Combipack Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Femoston 2/10 Combipack Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolExemestane
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Using Femoston 2/10 Combipack Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Femoston 2/10 Combipack Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolPomalidomide
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Co-administration of Femoston 2/10 Combipack Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Femoston 2/10 Combipack Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolLenalidomide
Severe
How does the drug interact with Femoston 2/10 Combipack Tablet:
Coadministration of Femoston 2/10 Combipack Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Femoston 2/10 Combipack Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wear loose, layered clothing during the nighttime, especially in warm weather. This prevents hot flushes.
  • Manage your weight. Shed excess weight by exercising regularly if you are obese or overweight. 
  • Talk to a psychologist if you feel low, sad, isolated, or have sleeping issues.
  • Limit alcohol intake and quit smoking.
  • Try to eat foods that are rich in iron and Vitamin C, including red meat, shellfish, eggs, beans, and leafy green vegetables.

Habit Forming

No

Therapeutic Class

HORMONES

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • RIFAMPICIN
  • EFAVIRENZ
  • RITONAVIR
  • FENTANYL
  • THEOPHYLLINE
  • CYCLOSPORINE

Special Advise

  • Regular breast screening is recommended while taking Femoston 2/10 Combipack Tablet 28's.
  • Check your breasts regularly for any changes in the nipple, dimpling of the skin or any lumps.
  • While giving blood for tests, inform your doctor that you are taking Femoston 2/10 Combipack Tablet 28's as this medicine may affect some test results. 

Disease/Condition Glossary

Post menopause: Menopause occurs when a woman is between 45 and 55 and has not had a period for 12 months or more. Post-menopause is a condition in which women have not had a period for 12 months or longer. The oestrogen levels decrease in postmenopausal women resulting in symptoms such as hot flushes (hot neck, face and chest).

Osteoporosis: It is a bone disease that weakens and thins bones by decreasing bone density.  As the density of bones decreases, they weaken and are more likely to break. Post-menopausal women are more likely to develop osteoporosis than men because, at menopause, a woman’s ovaries stop the production of oestrogen (a female hormone), which is essential to keep bones healthy. Following menopause, bone loss occurs, making bones weak and more likely to break. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.

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