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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
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Whats That

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Synonym :

FENOFIBRIC ACID

Composition :

FENOFIBRATE-145MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Fenabrate-145 Tablet

Fenabrate-145 Tablet belongs to a group of medications called 'fibric acid derivatives or 'fibrates' primarily used to treat raised or increased cholesterol levels or fat/oils. Hyperlipidemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased level of bad cholesterol leads to a high risk of heart attack and stroke in future, especially for heart disease patients.

Fenabrate-145 Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fenabrate-145 Tablet decreases harmful cholesterol like LDL (bad cholesterol) triglycerides (TG) and increases levels of HDL (good cholesterol).

Always take the Fenabrate-145 Tablet exactly as prescribed by your doctor. Some people may experience nausea, chest pain, vomiting, diarrhoea, drowsiness, muscle pain, redness/swelling in the legs and increased liver enzymes. Most of these side effects of Fenabrate-145 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Fenabrate-145 Tablet for as long as your doctor has prescribed it. Do not use Fenabrate-145 Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using Fenabrate-145 Tablet if you are pregnant or breastfeeding. Fenabrate-145 Tablet is not recommended for children under the age of 18, as the safety and effectiveness were not established. Avoiding alcohol is recommended to rule out any possibility of side effects.

Uses of Fenabrate-145 Tablet

Hyperlipidemia or High cholesterol 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Fenabrate-145 Tablet contains 'fenofibrate', which is used along with a proper diet to help lower 'bad cholesterol' (LDL, TG -triglycerides) and raise 'good cholesterol' (HDL) in the blood. Fenabrate-145 Tablet is also used with statins to lower raised cholesterol. Besides this, Fenabrate-145 Tablet also helps in the treatment of raised cholesterol in diabetes and high blood pressure patients as well.

Storage

Store in a cool and dry place away from sunlight
Side effects of Fenabrate-145 Tablet
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid smoking and intake of any tobacco products as it worsens respiratory disorders.
  • Get a physical examination, follow your doctor's instructions, and get required vaccinations.
  • Be physically active and eat healthy food.
  • Prefer practising yoga and meditation to reduce stress and anxiety.
  • Practice good hygiene and stay away from places where air pollution is high.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.

Drug Warnings

Before taking the Fenabrate-145 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Inform your doctor if you are suffering from bladder problems, gallstones, liver disease, kidney disease, or muscle problems (like muscle pain, myopathy, or rhabdomyolysis). If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Keep your doctor informed about your health condition and all the medicines you are taking before taking Fenabrate-145 Tablet to rule out any side effects. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness. Fenabrate-145 Tablet is not recommended in children below 18 years of age.

Drug-Drug Interactions

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FenofibrateAtorvastatin
Severe
FenofibrateLeflunomide
Severe

Drug-Drug Interactions

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FenofibrateAtorvastatin
Severe
How does the drug interact with Fenabrate-145 Tablet:
Coadministration of Fenabrate-145 Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Fenabrate-145 Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FenofibrateLeflunomide
Severe
How does the drug interact with Fenabrate-145 Tablet:
Co- administration of Fenabrate-145 Tablet with Leflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fenabrate-145 Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Fenabrate-145 Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateDicoumarol
Severe
How does the drug interact with Fenabrate-145 Tablet:
co-administration of Fenabrate-145 Tablet with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.

How to manage the interaction:
Taking Fenabrate-145 Tablet with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
FenofibrateRosuvastatin
Severe
How does the drug interact with Fenabrate-145 Tablet:
Co-administration of Rosuvastatin and Fenabrate-145 Tablet can increase the blood levels of rosuvastatin and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rosuvastatin and Fenabrate-145 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateMipomersen
Severe
How does the drug interact with Fenabrate-145 Tablet:
Mipomersen may cause liver problems and using it with Fenabrate-145 Tablet may increase that risk.

How to manage the interaction:
There may be a possibility of interaction between Fenabrate-145 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
FenofibrateSimvastatin
Severe
How does the drug interact with Fenabrate-145 Tablet:
The use of Fenabrate-145 Tablet and simvastatin can increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue), rhabdomyolysis can cause kidney damage. If you are elderly or have preexisting kidney disease, the risk may increase.

How to manage the interaction:
Co-administration of Fenabrate-145 Tablet and simvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateAtorvastatin
Severe
How does the drug interact with Fenabrate-145 Tablet:
When atorvastatin is used with Fenabrate-145 Tablet, it increases the risk of side effects such as liver damage, rhabdomyolosis (uncommon illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Fenabrate-145 Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FenofibrateTeriflunomide
Severe
How does the drug interact with Fenabrate-145 Tablet:
Co- administration of Fenabrate-145 Tablet with teriflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fenabrate-145 Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Teriflunomide and Fenabrate-145 Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateLomitapide
Severe
How does the drug interact with Fenabrate-145 Tablet:
Co-administration of Lomitapide with Fenabrate-145 Tablet may cause liver damage and using it with other drugs that might adversely impact the liver, such as Fenabrate-145 Tablet, may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Fenabrate-145 Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
FenofibrateCerivastatin
Severe
How does the drug interact with Fenabrate-145 Tablet:
When Fenabrate-145 Tablet is used with cerivastatin, the risk of adverse effects such as liver damage and rhabdomyolysis, an uncommon but serious illness involving the breakdown of skeletal muscle tissue, increases. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Although taking Fenabrate-145 Tablet and Cerivastatin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience unexplained muscular pain, soreness, or weakness while taking these drugs, inform a doctor immediately, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eating a proper diet (such as a low-cholesterol/low-fat diet) and other lifestyle changes that may help this medication work better include exercising, losing weight if overweight and stopping smoking.
  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.
  • Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
  • Contact your healthcare provider immediately if you notice slurred speech, confusion, severe weakness or difficulty breathing.

 

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Fenabrate-145 Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fenabrate-145 Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

You should not take Fenabrate-145 Tablet if you are allergic to fibric acid derivative or Fenabrate-145 Tablet , have a severe renal impairment (including dialysis patient), have active liver disease, gallbladder disease (gallstone) or are a nursing mother.

Increased liver enzymes (like liver function tests - LFTs), rhinitis, stuffy/runny nose, nausea, indigestion, headache and back pain are some common side effects that may occur in some cases.

No, Fenabrate-145 Tablet does not reduce the risk of having heart problems in patients with type 2 diabetes.

Long-term complications of Fenabrate-145 Tablet are muscle problems (like unexplained muscle pain) and liver problems (with increased liver enzymes). So, if you experience these symptoms, please consult a doctor.

Fenabrate-145 Tablet raises the risk of muscle pain and a serious muscle problem called rhabdomyolysis. The risk is higher if you take the drug along with statins.

It is completely fine to use oral contraceptives with Fenabrate-145 Tablet as no such interactions have been found. Consult your doctor for further advice.

Drug-Drug Interactions Checker List

  • WARFARIN
  • COLCHICINE
  • CLOFIBRATE
  • GEMFIBROZIL
  • EZETIMIBE

Special Advise

  • Cholelithiasis can occur with the use of Fenabrate-145 Tablet , so discontinue if any gallstones are detected.
  • Breast-feeding is not recommended while using this drug and for five days after stopping the medication. Consult your doctor before breastfeeding.
  • If you are already taking any blood thinner, regular monitoring of bleeding time should be done.
  • Regular liver function tests (LFT) and kidney function tests (KFT) are suggested if you are taking Fenabrate-145 Tablet for a prolonged time.

Disease/Condition Glossary

Hyperlipidemia/High cholesterol: When the concentration of cholesterol (like lipids/oil/fats) in your blood is too high, this condition is called hyperlipidemia. Lipids are made naturally in our bodies and also taken from external foods. The liver breaks down these fats for further use.  If the levels of lipids are too high, the excess fat is deposited onto the walls of the heart's blood vessels of the heart, which can lead to plaque formation within the lining of arteries, leading to clogged arteries. These clogged arteries can increase the risk of stroke and heart attack. 

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