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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

FLUCONAZOLE-150MG

Manufacturer/Marketer :

Eskon Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Flunise 150 Tablet

Flunise 150 Tablet belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused due to fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

Flunise 150 Tablet contains ‘Fluconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Take this medicine as prescribed by your doctor. Flunise 150 Tablet has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to Flunise 150 Tablet or any of its components. Let your doctor know if you have any liver, kidney or heart problems before starting Flunise 150 Tablet . Pregnant and breastfeeding women should consult their doctor before starting Flunise 150 Tablet . It is advised to avoid alcohol intake while using Flunise 150 Tablet to prevent any undesirable effects.

Uses of Flunise 150 Tablet

Fungal infections.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Flunise 150 Tablet works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. It is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Flunise 150 Tablet is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Flunise 150 Tablet is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs.

Storage

Store in a cool and dry place away from sunlight
Side effects of Flunise 150 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using Flunise 150 Tablet . Do not use Flunise 150 Tablet if you are allergic to Flunise 150 Tablet or any of its components. Let your doctor know if you have any liver, kidney, or heart problems before starting Flunise 150 Tablet . This medicine may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels; however, please seek medical advice. Pregnant or lactating women should consult the doctor before taking the Flunise 150 Tablet . Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Flunise 150 Tablet to avoid undesirable effects 

Drug-Drug Interactions

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FluconazoleLomitapide
Critical
FluconazoleErythromycin
Critical

Drug-Drug Interactions

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FluconazoleLomitapide
Critical
How does the drug interact with Flunise 150 Tablet:
When Lomitapide is taken with Flunise 150 Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Flunise 150 Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Flunise 150 Tablet:
Taking Flunise 150 Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Flunise 150 Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Flunise 150 Tablet:
When Astemizole is taken with Flunise 150 Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Flunise 150 Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with Flunise 150 Tablet:
When Eliglustat and Flunise 150 Tablet are taken together, Flunise 150 Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Flunise 150 Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleMoxifloxacin
Severe
How does the drug interact with Flunise 150 Tablet:
Taking Flunise 150 Tablet with Moxifloxacin can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Flunise 150 Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience dizziness, shortness of breath, or irregular heartbeat consult a doctor. Do not discontinue the medications without consulting a doctor.
FluconazoleDicoumarol
Severe
How does the drug interact with Flunise 150 Tablet:
Taking Flunise 150 Tablet with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, Flunise 150 Tablet can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.
FluconazoleBrigatinib
Severe
How does the drug interact with Flunise 150 Tablet:
Taking Flunise 150 Tablet with Brigatinib can raise the levels of Brigatinib in the blood, which may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction, Flunise 150 Tablet can be taken with Brigatinib if prescribed by the doctor. Consult the prescriber if you experience paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain and burning during urination. Do not discontinue the medications without a doctor's advice.
FluconazoleTacrolimus
Severe
How does the drug interact with Flunise 150 Tablet:
Taking Flunise 150 Tablet may increase the blood levels of Tacrolimus and may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction, Flunise 150 Tablet can be taken with tacrolimus if prescribed by the doctor. However, consult the doctor if you experience signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
FluconazoleGlimepiride
Severe
How does the drug interact with Flunise 150 Tablet:
Co-administration of Flunise 150 Tablet may increase the blood levels and effects of Glimepiride may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Flunise 150 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FluconazoleLemborexant
Severe
How does the drug interact with Flunise 150 Tablet:
Taking lemborexant with Flunise 150 Tablet may increase the blood levels of lemborexant. This may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Lemborexant and Flunise 150 Tablet, but it can be taken if prescribed by a doctor. However, if you experience depression, abnormal sleep behaviors, worsening of depression, changes in heartbeat, or headache, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.
  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol, and includes low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Flunise 150 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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FLUCONAZOLE-150MGOther diseases of liver
Severe
FLUCONAZOLE-150MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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FLUCONAZOLE-150MGOther diseases of liver
Severe
How does the disease interact with Flunise 150 Tablet:
Hepatotoxicity has only sometimes been linked to the usage of Flunise 150 Tablet. There have been cases of reversible idiosyncratic hepatitis, cholestasis, and deadly fulminant hepatic failure; the latter generally affects people with substantial underlying medical disorders who are also taking several concurrent drugs. Patients with pre-existing hepatic problems should have periodic liver function tests done, especially during prolonged medication. If liver enzyme levels continue to rise or worsen, treatment should be stopped.

How to manage the interaction:
In patients with preexisting liver abnormalities, particularly during prolonged therapy, liver function tests should be done regularly. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur.
FLUCONAZOLE-150MGOther cardiac arrhythmias
Moderate
How does the disease interact with Flunise 150 Tablet:
The QT interval on the ECG has been shown to be prolonged by some azole antifungals. During postmarketing experience, there have been a few isolated incidences of QT prolongation and torsade de pointes; these reports typically involved critically ill patients with a number of complicating risk factors, including structural cardiac disease, electrolyte problems, and concurrent medicines. Patients with illnesses that could cause proarrhythmic symptoms should take these medications cautiously. It is best to avoid using drugs that could potentially enhance the risk of cardiotoxicity concurrently.

How to manage the interaction:
It should be administered with caution to patients with heart problems. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.
FLUCONAZOLE-150MGCare involving dialysis
Moderate
How does the disease interact with Flunise 150 Tablet:
Hemodialysis effectively removes Flunise 150 Tablet from the body. Following three hours of dialysis, it has been demonstrated that plasma levels of Flunise 150 Tablet decrease by 50%. After hemodialysis, Flunise 150 Tablet should be taken.

How to manage the interaction:
Flunise 150 Tablet should be administered after hemodialysis.

FAQs

Flunise 150 Tablet contains Fluconazole, an antifungal drug, which works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.

Do not stop using Flunise 150 Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.

The usual recommendation of dosage for Flunise 150 Tablet can be for a short time. However, your doctor may prescribe it for a longer time, depending on the type and severity of your infection.

Flunise 150 Tablet may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, it is advised to seek a doctor's advice before starting Flunise 150 Tablet if you have a previous medical history.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • QUETIAPINE
  • ERYTHROMYCIN
  • ERGOTAMINE
  • AMIODARONE
  • WARFARIN
  • CARBAMAZEPINE
  • LOSARTAN
  • METFORMIN
  • REBOXETINE

Special Advise

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Disease/Condition Glossary

Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by the species Candida. 

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