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  3. Fonaxel Injection 0.5 ml

Fonaxel Injection 0.5 ml, Pack of 1 INJECTION
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Composition :

FONDAPARINUX SODIUM-2.5MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fonaxel Injection

Fonaxel Injection belongs to a class of drugs called anticoagulants (blood thinner) primarily used to prevent/treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), heart attack, and severe angina. It also reduces the risk of blood clots after orthopedic (such as hip or knee surgery), or abdominal surgery. Fonaxel Injection prevents blood clot formation during and shortly after restricted movement because of an acute illness. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Fonaxel Injection contains ‘Fondaparinux sodium’ that works by inhibiting the action of clotting factors (a natural substance in the blood that causes clotting). Thereby preventing the conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helping prevent blood clot formation. It eases blood flow through the veins, making it less likely to develop a severe blood clot.

Fonaxel Injection will be administered by a trained healthcare professional; hence do not self-administer. Some people may experience unusual bleeding, anemia (low number of red blood cells), bruising or swelling. Most of these side effects of Fonaxel Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to consult a doctor before using Fonaxel Injection . Fonaxel Injection is not recommended for children below 17 years of age. Fonaxel Injection should be used with caution in the elderly above 60, as they may be at high risk of bleeding. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before receiving Fonaxel Injection . If you are about to undergo surgery, inform your doctor about the treatment with Fonaxel Injection . Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Fonaxel Injection

Prevents blood clot formation

Directions for Use

Fonaxel Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Fonaxel Injection belongs to a class of drugs known as anticoagulants or blood thinners. Fonaxel Injection contains ‘Fondaparinux sodium’ used to prevent deep vein thrombosis (blood clot in the blood vessels of legs) and pulmonary embolism (blood clot in the blood vessels lungs). It also reduces the risk of blood clots during orthopedic (such as hip or knee surgery), abdominal surgery, or restricted movement because of an acute illness. Fonaxel Injection works by stopping the action of clotting factor Xa (a natural substance in the blood that causes clotting). This inhibits fibrin production (a protein that binds platelets together and forms a clot), preventing blood clot formation. Fonaxel Injection is also used to treat certain types of heart attack and chest pain called unstable angina.

Storage

Store in a cool and dry place away from sunlight
Side effects of Fonaxel Injection 0.5 ml
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Do not receive Fonaxel Injection if you are allergic to any of the contents; if you are bleeding excessively, have a bacterial heart infection, or have very severe kidney disease. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Fonaxel Injection . Fonaxel Injection is not recommended for children as safety and effectiveness have not been established. Fonaxel Injection should be used with caution in the elderly above 65, as they may be at high risk of bleeding. If you are about to undergo any surgery, inform your doctor that you are receiving Fonaxel Injection . If you notice bleeding gums, blood in urine, coughing up blood or vomit that looks like coffee grounds, pain, swelling, dizziness, weakness, unusual bruising, nose bleeds, abnormal vaginal bleeding or heavy menstrual periods, bloody or tarry stools, please consult a doctor immediately. Avoid alcohol consumption during treatment with Fonaxel Injection as it may increase the risk of stomach bleeding. Inform your doctor before receiving Fonaxel Injection if you have a stomach ulcer, kidney or liver problems, high blood pressure, bleeding problems, are 75 years or older, or weigh less than 50kg. Do not discontinue using Fonaxel Injection  without consulting your doctor, as this may increase your chances of having another heart attack or stroke.

Drug-Drug Interactions

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FondaparinuxMifepristone
Critical
FondaparinuxDefibrotide
Critical

Drug-Drug Interactions

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FondaparinuxMifepristone
Critical
How does the drug interact with Fonaxel Injection 0.5 ml:
Using mifepristone together with Fonaxel Injection 0.5 ml may increase the risk and/or severity of vaginal bleeding in women

How to manage the interaction:
Taking Fonaxel Injection 0.5 ml with Mifepristone together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FondaparinuxDefibrotide
Critical
How does the drug interact with Fonaxel Injection 0.5 ml:
Taking defibrotide with Fonaxel Injection 0.5 ml can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Fonaxel Injection 0.5 ml with Defibrotide is not recommended, but it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FondaparinuxApixaban
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Coadministration of Fonaxel Injection 0.5 ml with Apixaban may raise the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fonaxel Injection 0.5 ml and Apixaban, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience blood in urine or stool (or a black stool), severe bruising, weakness or severe headache, or heavy menstrual bleeding (in women). Do not discontinue any medications without consulting a doctor.
FondaparinuxDiclofenac
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Coadministration of diclofenac with Fonaxel Injection 0.5 ml may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Fonaxel Injection 0.5 ml when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FondaparinuxCangrelor
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Taking Cangrelor with Fonaxel Injection 0.5 ml can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Cangrelor and Fonaxel Injection 0.5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not stop using any medications without talking to a doctor.
FondaparinuxBivalirudin
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Coadministration of bivalirudin with Fonaxel Injection 0.5 ml can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Bivalirudin and Fonaxel Injection 0.5 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not discontinue any medications without consulting a doctor.
FondaparinuxDextran
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Taking Fonaxel Injection 0.5 ml with dextran can increase the risk of bleeding.

How to manage the interaction:
Taking Dextran with Fonaxel Injection 0.5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FondaparinuxKetorolac
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Taking ketorolac with Fonaxel Injection 0.5 ml can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Fonaxel Injection 0.5 ml and Ketorolac, but it can be taken together if prescribed by a doctor. However, if you experience bleeding or bruising, feeling dizzy or lightheaded, dark or bloody stools, headache, weakness contact your doctor right away. Do not stop using any medications without first talking to your doctor.
FondaparinuxTiclopidine
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
taking ticlopidine with Fonaxel Injection 0.5 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Fonaxel Injection 0.5 ml and Ticlopidine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FondaparinuxDalteparin
Severe
How does the drug interact with Fonaxel Injection 0.5 ml:
Taking Fonaxel Injection 0.5 ml with dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin and Fonaxel Injection 0.5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not make any changes in your diet without first talking to your doctor.
  • Avoid vitamin K-rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and brussels sprouts as they may decrease the effectiveness of Fonaxel Injection .
  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice and green tea as they may interact with Fonaxel Injection and lead to unwanted side effects.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid consumption of alcohol as it may increase the risk of bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Fonaxel Injection Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:41 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Fonaxel Injection stops the action of clotting factors. This prevents the formation of unwanted blood clots (thrombosis) in the blood vessels.

If you have diabetes, inform your doctor before receiving Fonaxel Injection . Fonaxel Injection should be used with caution in diabetic patients as they may be at increased risk of bleeding. Regular blood tests are advised to monitor blood clotting time while receiving Fonaxel Injection .

You are not recommended to take aspirin with Fonaxel Injection as co-administration of these two medicines may increase the risk of haemorrhage. However, please consult a doctor immediately if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately.

Yes, Fonaxel Injection may increase the risk of bleeding, and the effects of Fonaxel Injection may last for four days even after discontinuation. Always be careful while doing activities that may cause injury or bleeding. Please inform your doctor immediately if you notice purple spots on the skin, unusual bruising, blood in urine, black tarry stools, or unusual bleeding from the gums or nose.

Tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) are used to determine blood clotting time.

You are usually not advised to have a tattoo or body piercing while receiving Fonaxel Injection as it may increase the risk of bleeding and infection. If you still wish to proceed further, contact your doctor to adjust the dose, or any antibiotics may be prescribed. Let the piercer or tattooist know in advance that you are on treatment with a blood thinner.

Please consult your doctor if you are due to undergo any surgery. The doctor might stop the administration of Fonaxel Injection a few days before surgery as it can cause an increased risk of bleeding during surgery.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CELECOXIB
  • HEPARIN

Special Advise

  • To analyze your blood clotting time, regular tests such as platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and INR (International Normalized Ratio) are advised.

Disease/Condition Glossary

Blood clot: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots help stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels, inhibit blood flow to essential organs such as the brain, heart or lungs, and result in severe conditions. The common risk factors for blood clots are obesity, smoking, cancer, family history of blood clots, age over 65, and certain birth control pills or pregnancy.


Deep vein thrombosis: Deep vein thrombosis (blood clots in the legs) is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 


Pulmonary embolism: Pulmonary embolism (blood clots in the lung) is a blockage in the lung arteries. It is caused by blood clots that travel from the legs or other body parts. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath.

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