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Written By ,
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer

Getwell Oncology Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Fosfa 1 gm With Mesna Injection

Fosfa 1 gm With Mesna Injection belongs to a group of medications called ‘anti-neoplastic'. It is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer (a type of cancer that begins in the ovaries), testicular cancer (cancer occurs in the testicles (testes), (which are located inside the scrotum, a loose bag of skin underneath the penis), and pancreatic cancer (a type of cancer that begins in the pancreas). Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell).

Fosfa 1 gm With Mesna Injection contains ‘ifosfamide’, which is an anti-cancer drug. Fosfa 1 gm With Mesna Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Fosfa 1 gm With Mesna Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Fosfa 1 gm With Mesna Injection do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Fosfa 1 gm With Mesna Injection if you are allergic to any other ingredients present in it. Do not self-administer Fosfa 1 gm With Mesna Injection. Before taking Fosfa 1 gm With Mesna Injection, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases, bone marrow suppression, cystitis, CNS toxicity. Fosfa 1 gm With Mesna Injection is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Fosfa 1 gm With Mesna Injection. It is not recommended for use in children under 1 year of age. 

Uses of Fosfa 1 gm With Mesna Injection

Blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer.

Directions for Use

Fosfa 1 gm With Mesna Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Fosfa 1 gm With Mesna Injection contains ‘ifosfamide’, which is an anti-cancer drug. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Fosfa 1 gm With Mesna Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fosfa 1 gm With Mesna Injection

  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Hair loss
  • Decreased white blood cell count
  • Infection
  • Blood in urine
  • CNS toxicity
  • Dehydration
  • Dry mouth/increased thirst
  • Pale/wrinkled skin
  • Temporary hair loss
  • Trouble breathing

Drug Warnings

Do not take Fosfa 1 gm With Mesna Injection if you are allergic to any other ingredients present in it. Do not self-administer Fosfa 1 gm With Mesna Injection. Before taking Fosfa 1 gm With Mesna Injection, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases,  cystitis, CNS toxicity. Fosfa 1 gm With Mesna Injection is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Fosfa 1 gm With Mesna Injection. It is not recommended for use in children under 1 year of age. Fosfa 1 gm With Mesna Injection should be used with caution in infections. Because the chances of infections are more in patients receiving this medicine. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary. Consumption of alcohol is not recommended while receiving this Fosfa 1 gm With Mesna Injection as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, seizures. Fosfa 1 gm With Mesna Injection may cause bone marrow suppression, which lowers the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary.

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
IfosfamideThalidomide
Severe

Drug-Drug Interactions

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IfosfamideCidofovir
Critical
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Taking cidofovir with Fosfa 1 gm With Mesna Injection can increase the risk of kidney problems.

How to manage the interaction:
Taking Fosfa 1 gm With Mesna Injection with Cidofovir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IfosfamideThalidomide
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Taking thalidomide together with Fosfa 1 gm With Mesna Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Fosfa 1 gm With Mesna Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
IfosfamideCladribine
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Combining Cladribine with Fosfa 1 gm With Mesna Injection can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Fosfa 1 gm With Mesna Injection and Cladribine, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
IfosfamideInfliximab
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Combining Infliximab with Fosfa 1 gm With Mesna Injection can speed up the breakdown of Fosfa 1 gm With Mesna Injection in the body. This can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Fosfa 1 gm With Mesna Injection with Infliximab can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, contact a doctor right away. Don't hesitate to reach out to your doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
IfosfamideTofacitinib
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Taking Fosfa 1 gm With Mesna Injection with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Fosfa 1 gm With Mesna Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
IfosfamideLidocaine
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Coadministration of Fosfa 1 gm With Mesna Injection with Lidocaine can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Fosfa 1 gm With Mesna Injection and Lidocaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
IfosfamideTenofovir alafenamide
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
The combined use of Fosfa 1 gm With Mesna Injection and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Fosfa 1 gm With Mesna Injection and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IfosfamideBupivacaine
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Taking Bupivacaine and Fosfa 1 gm With Mesna Injection may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Fosfa 1 gm With Mesna Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
IfosfamideClozapine
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
Co-administration of Fosfa 1 gm With Mesna Injection with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
Taking Fosfa 1 gm With Mesna Injection with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection like fever, chills, or a sore throat, or experience discomfort while urinating, it's best to contact a doctor right away. Do not stop using any medications without a doctor's advice.
IfosfamideEtanercept
Severe
How does the drug interact with Fosfa 1 gm With Mesna Injection:
When Etanercept is used with Fosfa 1 gm With Mesna Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Fosfa 1 gm With Mesna Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a variety of protein-rich foods that are low in fat. Include seafood, lean meat and poultry, greek yoghurts, eggs, beans, soy products, and unsalted nuts and seeds.
  • Take vitamin A foods, found in green- or orange-coloured fruits and vegetables, such as sweet potatoes, carrots, kale, spinach, and apricots.
  • Stay away from strong-smelling foods to avoid aggravating any disorders of taste.
  • Avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea.
  • Avoid refined sugars (including raw, brown, and palm sugar) and refined carbohydrates, as most tumours prefer glucose as an energy source.
  • Avoid drinking alcohol.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CISPLATIN
  • AMPHOTERICIN B
  • RIFAMPIN
  • DILITAZEM
  • ENALAPRIL
  • CLOZAPINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • FLUCONAZOLE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • ETANERCEPT
  • ADALIMUMAB

Special Advise

  • Regular monitoring of kidney, liver function, and levels of blood cells in your blood.
  • Drink plenty of fluids while taking this Fosfa 1 gm With Mesna Injection to minimize damage to your bladder and kidneys.

Disease/Condition Glossary

Blood cancer:  Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell). Symptoms include fever, chills., fatigue, weakness, bone and joint pain, weight loss.

Ovarian cancer:  Ovarian cancer is when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body. This is called metastatic ovarian cancer. Symptoms include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.

Breast cancer: Cancer that forms in the cells of the breasts. Breast cancer can occur in women and rarely in men. Symptoms of breast cancer include a lump in the breast, bloody discharge from the nipple, and changes in the shape or texture of the nipple or breast.

Testicular cancer: Testicular cancer occurs in the testicles (testes), located inside the scrotum, a loose bag of skin underneath the penis. Symptoms include a painless lump or swelling on either testicle, pain, discomfort, numbness in a testicle or the scrotum, change in the way a testicle feels, or a feeling of heaviness the scrotum, a dull ache in the lower abdomen or groin. Sudden buildup of fluid in the scrotum.

Pancreatic cancer: Pancreatic cancer is cancer that forms in the cells of the pancreas. Pancreatic cancer begins in your pancreas tissues — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produce hormones that help manage your blood sugar. Symptoms include abdominal pain that radiates to your back, loss of appetite or unintended weight loss, yellowing of your skin and the whites of your eyes (jaundice), light-colored stools, dark-colored urine, itchy skin.

Non-small cell lung cancer: Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that won't go away, shortness of breath, weight loss, or coughing up blood.

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