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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

PHENYLEPHRINE-10MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Frenin Injection 1 ml

Frenin Injection 1 ml belongs to a class of medications called anti-hypotensives used to treat hypotension (low blood pressure) caused by spinal anaesthesia, circulatory failure or certain other medicines. Also, it is used to treat low blood pressure during surgery or after an injury. Hypotension is a condition in which the blood flows through the blood vessels at lower than normal pressures. Low blood pressure symptoms include tiredness, dizziness, light-headedness, loss of consciousness, nausea, depression, blurry vision, or clammy (wet or sweaty) skin.

Frenin Injection 1 ml contains Phenylephrine that works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

Frenin Injection 1 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience headache, vomiting, sweating, nervousness, tremor, shortness of breath, difficulty in passing urine or irregular heartbeat. Most of these side effects of Frenin Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Phenylephrine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Frenin Injection 1 ml. Discuss with your doctor if you want to drive or operate machinery after receiving Frenin Injection 1 ml. Caution is advised when drinking alcohol while you are receiving Frenin Injection 1 ml.

Uses of Frenin Injection 1 ml

Hypotension (low blood pressure)

Directions for Use

Frenin Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Frenin Injection 1 ml contains Phenylephrine, an anti-hypotensive agent used to treat low blood pressure caused by spinal anaesthesia, circulatory failure or certain other medicines. Also, it is used to treat low blood pressure during surgery or after an injury. It works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please tell your doctor if you are allergic to Phenylephrine or other medicines. If you are pregnant or breastfeeding, please inform your doctor before receiving Frenin Injection 1 ml. Discuss with your doctor if you want to drive or operate machinery after receiving Frenin Injection 1 ml. Caution is advised when drinking alcohol while you are receiving Frenin Injection 1 ml. Frenin Injection 1 ml should not be given to you if you are taking or have taken monoamine oxidase (MAO) inhibitor medicines (used for depression) in the past 14 days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Frenin Injection 1 ml:
Taking Frenin Injection 1 ml with Propofol may lead to increased levels of Frenin Injection 1 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Frenin Injection 1 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Selegiline with Frenin Injection 1 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Frenin Injection 1 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Frenin Injection 1 ml:
Taking Furazolidone with Frenin Injection 1 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Frenin Injection 1 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Frenin Injection 1 ml only after 14 days of stopping Furazolidone.
How does the drug interact with Frenin Injection 1 ml:
Taking Tranylcypromine with Frenin Injection 1 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Frenin Injection 1 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Sevoflurane can increase the levels of Frenin Injection 1 ml and lead to side effects.

How to manage the interaction:
Taking Frenin Injection 1 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineMethoxyflurane
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Methoxyflurane can increase the side effects of Methoxyflurane.

How to manage the interaction:
There may be a possibility of interaction between Frenin Injection 1 ml and Methoxyflurane, but it can be taken if prescribed by a doctor. Do not discontinue any medications without doctor's advice.
PhenylephrineMethysergide
Severe
How does the drug interact with Frenin Injection 1 ml:
Taking Frenin Injection 1 ml and Methysergide together may lead to side effects like increased blood pressure, stomach problems, and gangrene (death of tissues, usually in the arm or leg, that may require surgical treatment).

How to manage the interaction:
Although there is a possible interaction between Frenin Injection 1 ml and Methysergide, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms like severe stomach pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, severe headache, irregular heartbeat, breathing difficulties, blurred vision, confusion, and/or slurred speech, consult the doctor immediately.
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Halothane may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Frenin Injection 1 ml with Halothane together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms like lightheadedness, fainting, irregular heart beat, dizziness, consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Procarbazine raises blood pressure excessively which may show serious effects.

How to manage the interaction:
Although taking Frenin Injection 1 ml and Procarbazine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PhenylephrinePhenelzine
Severe
How does the drug interact with Frenin Injection 1 ml:
Co-administration of Frenin Injection 1 ml with Phenelzine can result in extremely high blood pressure which may be serious.

How to manage the interaction:
There may be a possibility of interaction between Frenin Injection 1 ml and Phenelzine, but it can be taken if prescribed by a doctor. However, If you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.
  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
  • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
  • Eat foods rich in folates such as beans, asparagus, lentils, leafy greens, citrus fruits, liver, and eggs.
  • Try to eat smoked fish, canned soup, pickled items, cottage cheese, and olives, as salty foods can also increase blood pressure.
  • Take frequent breaks if you exercise outdoors in extreme heat.
  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIHYPOTENSIVES

Frenin Injection 1 ml Substitute

Substitutes safety advice
  • PHENPRES 10MG INJECTION 1ML

    by Others

    356.40per tablet
  • Phrintec 10 mg Injection 1 ml

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    274.50per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Frenin Injection 1 ml contains Phenylephrine that works by constricting and narrowing blood vessels by acting on alpha receptors. Thus, it increases blood pressure and decreases heart rate.

Phenylephrine in Frenin Injection 1 ml may worsen heart failure due to constriction of blood vessels. Therefore, inform your doctor if you have heart failure or any other heart problem before receiving Frenin Injection 1 ml.

Frenin Injection 1 ml may cause a headache as a temporary side effect. However, if the condition persists or worsens, please inform your doctor.

Drug-Drug Interactions Checker List

  • IMIPRAMINE
  • LINEZOLID
  • PHENELZINE
  • IPRONIAZID
  • NIALAMIDE
  • OXYTOCIN
  • GUANETHIDINE
  • QUINIDINE
  • ATOMOXETINE
  • ATROPINE
  • LITHIUM
  • Pergolide
  • BROMOCRIPTINE

Disease/Condition Glossary

Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypotension (low blood pressure) is a condition in which the blood flows through the blood vessels at lower than normal pressures. Low blood pressure symptoms include dizziness, tiredness, lightheadedness, loss of consciousness, nausea, depression, blurry vision, or clammy (wet or sweaty) skin. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 90/60 mm of Hg, it means the systolic pressure is 90 mm of Hg, and diastolic pressure is 60 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 90/60 mmHg or lower, it is considered low blood pressure.

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