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  3. Fungisome 10Mg/10Ml Inj.

Fungisome 10Mg/10Ml Inj., Pack of 1 INJECTION
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

AMPHOTERICIN B-10MG

Manufacturer/Marketer :

Life Medicare & Diagnostic

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fungisome 10Mg/10Ml Inj.

Fungisome 10Mg/10Ml Inj. belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Fungisome 10Mg/10Ml Inj. contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Fungisome 10Mg/10Ml Inj. is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Fungisome 10Mg/10Ml Inj. do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Fungisome 10Mg/10Ml Inj. or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Fungisome 10Mg/10Ml Inj.. Fungisome 10Mg/10Ml Inj. is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Fungisome 10Mg/10Ml Inj. as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Fungisome 10Mg/10Ml Inj.

Severe fungal infections

Directions for Use

Fungisome 10Mg/10Ml Inj. will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Fungisome 10Mg/10Ml Inj. contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Fungisome 10Mg/10Ml Inj. damages fungal cell membranes and kills fungi. Fungisome 10Mg/10Ml Inj. is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Storage

Store in a cool and dry place away from sunlight
Side effects of Fungisome 10Mg/10Ml Inj.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Take pain reliever medicines such as ibuprofen or paracetamol.
  • Apply an ice pack for 15 minutes multiple times a day during the first 48 hours. Then, use a heating pad or take warm shower.
  • Gently stretch the neck and massage to relieve pain.
  • Good posture and gentle exercise may help to prevent it.
  • Maintain proper sleep hygiene.

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Fungisome 10Mg/10Ml Inj.. Fungisome 10Mg/10Ml Inj. is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Fungisome 10Mg/10Ml Inj. as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Fungisome 10Mg/10Ml Inj..

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
Amphotericin bIomeprol
Severe

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Taking Fungisome 10Mg/10Ml Inj. and streptozocin together can enhance kidney injury and can cause damage to the ear.

How to manage the interaction:
Taking Streptozocin with Fungisome 10Mg/10Ml Inj. is not recommended as it can result in an interaction, it can be taken if a doctor has advised it.
Amphotericin bIomeprol
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Coadministration of Fungisome 10Mg/10Ml Inj. and Iomeprol may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Fungisome 10Mg/10Ml Inj. with Iomeprol can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you experience any changes, like peeing more or less than usual, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without talking to a doctor.
Amphotericin bIoxilan
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Coadministration of Fungisome 10Mg/10Ml Inj. and Ioxilan may increase the risk of kidney problem.

How to manage the interaction:
Taking Fungisome 10Mg/10Ml Inj. with Ioxilan together can result in an interaction, but it can be taken if a doctor has advised it. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without a doctor's advice.
Amphotericin bZiprasidone
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Co-administration of Ziprasidone with Fungisome 10Mg/10Ml Inj. may raise the chance of a significantly abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Fungisome 10Mg/10Ml Inj. and Ziprasidone, but it can be taken if prescribed by a doctor. However, if you experience abrupt dizziness, lightheadedness, fainting, or rapid or pounding heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, contact a doctor immediately. You may need regular monitoring of your electrolyte (magnesium, potassium) levels. Do not stop using any medications without talking to a doctor.
Amphotericin bArsenic trioxide
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Using arsenic trioxide together with Fungisome 10Mg/10Ml Inj. cholesteryl sulfate can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Fungisome 10Mg/10Ml Inj. with Arsenic trioxide can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heartbeat, feeling suddenly dizzy or lightheaded, fainting, a fast or strong heartbeat, feeling weak or tired, feeling sleepy or confused, muscle pain, or feeling sick to your stomach. Do not stop using any medications without talking to a doctor.
Amphotericin bFoscarnet
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Using foscarnet together with Fungisome 10Mg/10Ml Inj. can cause serious side effects to the kidneys. Using these drugs together can also increase the risks of seizures (fits) and an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Fungisome 10Mg/10Ml Inj. and Foscarnet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach that spreads, strong heartbeats, feeling dizzy, or chest pain. Do not discontinue any medications without consulting a doctor.
Amphotericin bAdefovir dipivoxil
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Combining Fungisome 10Mg/10Ml Inj. with Adefovir dipivoxil can increase the risk of kidney damage.

How to manage the interaction:
Although taking Fungisome 10Mg/10Ml Inj. and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Do not stop using any medications without talking to a doctor.
Amphotericin bDroperidol
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Using droperidol together with Fungisome 10Mg/10Ml Inj. can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Fungisome 10Mg/10Ml Inj. and Droperidol together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - an irregular heart rhythm, a heart condition, a condition called congenital long qt syndrome, problems with your heart's conduction, severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, heart palpitations, feeling weak, feeling sleepy, feeling confused, muscle pain, feeling nauseous or vomiting - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Amphotericin bDronedarone
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Dronedarone used with Fungisome 10Mg/10Ml Inj. may raise the chance of a significantly abnormal heart rhythm, although it is a rare side effect.

How to manage the interaction:
Although there is a possible interaction between Fungisome 10Mg/10Ml Inj. and Dronedarone, you can take these medicines together if prescribed by a doctor. You should also notify a doctor if you suffer any of the following symptoms: weakness, weariness, sleepiness, disorientation, muscular pain, cramps, dizziness, nausea, or vomiting. Do not stop using any medications without talking to a doctor.
Amphotericin bIotalamic acid
Severe
How does the drug interact with Fungisome 10Mg/10Ml Inj.:
Coadministration of Fungisome 10Mg/10Ml Inj. and Iotalamic acid may decrease the excretion rate of Iothalamic acid which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Fungisome 10Mg/10Ml Inj. and Iotalamic acid, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:54 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Fungisome 10Mg/10Ml Inj. contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.

You are not recommended to take Fungisome 10Mg/10Ml Inj. with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Fungisome 10Mg/10Ml Inj. with other medicines.

Fungisome 10Mg/10Ml Inj. may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.

Yes, a test dose of Fungisome 10Mg/10Ml Inj. may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.

You are recommended to use Fungisome 10Mg/10Ml Inj. for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Fungisome 10Mg/10Ml Inj..

Fungisome 10Mg/10Ml Inj. is not used to treat viral infections. Fungisome 10Mg/10Ml Inj. is an antifungal that kills fungi and is used to treat severe fungal infections.

Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Special Advise

  • Regular blood tests are recommended while taking Fungisome 10Mg/10Ml Inj. to monitor blood, liver or kidney functioning and potassium levels.

Disease/Condition Glossary

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.

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