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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer

Aristo Pharmaceuticals Limited

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About GABASAFE PLUS TABLET

GABASAFE PLUS TABLET is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or malfunctioning of the nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful). A feeling of numbness and loss of sensations is also common with neuropathic pain.

GABASAFE PLUS TABLET is a combination of three drugs: Pregabalin (Anti-convulsant), mecobalamin (vitamin) and alpha-lipoic acid (antioxidant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Mecobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Together, GABASAFE PLUS TABLET helps in providing relief from neuropathic pain.

Take GABASAFE PLUS TABLET as prescribed. You are advised to take GABASAFE PLUS TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking GABASAFE PLUS TABLET without consulting your doctor as it could cause withdrawal symptoms. Consult your doctor before taking GABASAFE PLUS TABLET if you are pregnant or breastfeeding. GABASAFE PLUS TABLET causes drowsiness and dizziness, so drive only if you are alert. GABASAFE PLUS TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with GABASAFE PLUS TABLET as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and the medicines you take to rule out any side effects.

Uses of GABASAFE PLUS TABLET

Neuropathic pain

Directions for Use

Take GABASAFE PLUS TABLET with or without food as advised by the doctor. Swallow it as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

GABASAFE PLUS TABLET is used to treat neuropathic pain. GABASAFE PLUS TABLET is a combination of three drugs: Pregabalin, mecobalamin and alpha-lipoic acid. Pregabalin is an anticonvulsant that affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Mecobalamin is a form of vitamin B12 which helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that helps in providing a protective effect on the nerve tissues and brain. Together, GABASAFE PLUS TABLET helps in providing relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of GABASAFE PLUS TABLET

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Dry mouth
  • Constipation
  • Vomiting

Drug Warnings

Do not take GABASAFE PLUS TABLET if you are allergic to any of its contents. Inform your doctor before taking GABASAFE PLUS TABLET if you have or had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. GABASAFE PLUS TABLET may cause drowsiness and dizziness, so drive only if you are alert. GABASAFE PLUS TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with GABASAFE PLUS TABLET as it could lead to increased dizziness and sleepiness.

Drug-Drug Interactions

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PregabalinMethadone
Severe
PregabalinPethidine
Severe

Drug-Drug Interactions

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PregabalinMethadone
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Tapentadol together with Gabasafe Plus Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Gabasafe Plus Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinButorphanol
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Sodium oxybate together with Gabasafe Plus Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Gabasafe Plus Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinDezocine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinBuprenorphine
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Gabasafe Plus Tablet:
Using Gabasafe Plus Tablet together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Gabasafe Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

GABASAFE PLUS TABLET Substitute

Substitutes safety advice
  • Pregabid Forte 75 Capsule 10's

    by Others

    20.48per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • MIRTAZAPINE
  • FLUOXETINE
  • SERTRALINE
  • CODEINE
  • FENTANYL
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • GABAPENTIN
  • DIAZEPAM
  • ALPRAZOLAM
  • METFORMIN
  • CHLORAMPHENICOL

Special Advise

  • It is advised to rise slowly if you have been sitting or lying down, to decrease dizziness.
  • If you are experiencing any depression or suicidal thoughts discontinue the medicine and consult the doctor immediately.
  • Your doctor may recommend regular vision checks.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

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