GABASAFE PLUS TABLET

GABASAFE PLUS TABLET is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or malfunctioning of the nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful). A feeling of numbness and loss of sensations is also common with neuropathic pain.

GABASAFE PLUS TABLET is a combination of three drugs: Pregabalin (Anti-convulsant), mecobalamin (vitamin) and alpha-lipoic acid (antioxidant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Mecobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Together, GABASAFE PLUS TABLET helps in providing relief from neuropathic pain.

Take GABASAFE PLUS TABLET as prescribed. You are advised to take GABASAFE PLUS TABLET for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking GABASAFE PLUS TABLET without consulting your doctor as it could cause withdrawal symptoms. Consult your doctor before taking GABASAFE PLUS TABLET if you are pregnant or breastfeeding. GABASAFE PLUS TABLET causes drowsiness and dizziness, so drive only if you are alert. GABASAFE PLUS TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with GABASAFE PLUS TABLET as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and the medicines you take to rule out any side effects.

GABASAFE PLUS TABLET is used to treat neuropathic pain. GABASAFE PLUS TABLET is a combination of three drugs: Pregabalin, mecobalamin and alpha-lipoic acid. Pregabalin is an anticonvulsant that affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Mecobalamin is a form of vitamin B12 which helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that helps in providing a protective effect on the nerve tissues and brain. Together, GABASAFE PLUS TABLET helps in providing relief from neuropathic pain.

• Dizziness
• Sleepiness
• Tiredness
• Nausea
• Dry mouth
• Constipation
• Vomiting

Do not take GABASAFE PLUS TABLET if you are allergic to any of its contents. Inform your doctor before taking GABASAFE PLUS TABLET if you have or had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. GABASAFE PLUS TABLET may cause drowsiness and dizziness, so drive only if you are alert. GABASAFE PLUS TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with GABASAFE PLUS TABLET as it could lead to increased dizziness and sleepiness.

Drug-Drug Interactions: GABASAFE PLUS TABLET may have interaction with antidepressant medications (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline), anticonvulsants (gabapentin), anti-anxiety medications (diazepam, alprazolam), anti-diabetic medications (metformin), antibiotic medications (chloramphenicol), and pain killers (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol).

Drug-Food Interactions: Avoid consumption of alcohol while taking GABASAFE PLUS TABLET as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: GABASAFE PLUS TABLET may have interactions with disease conditions such as suicidal tendency, angioedema, creatine kinase elevations, peripheral oedema, malabsorption and anaemia.

• AMITRIPTYLINE
• DULOXETINE
• MIRTAZAPINE
• FLUOXETINE
• SERTRALINE
• CODEINE
• FENTANYL
• HYDROCODONE
• MORPHINE
• OXYCODONE
• TRAMADOL
• GABAPENTIN
• DIAZEPAM
• ALPRAZOLAM
• METFORMIN
• CHLORAMPHENICOL

• Include food rich in vitamin B and D in your diet.
• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
• Exercising regularly helps in improving overall health and combating pain. 
• Rest well, get plenty of sleep.
• Try taking a warm bath as it can be soothing.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
• Acupuncture can be helpful by stimulating pressure points.
• Using essential oils for massages can help increase circulation.

• It is advised to rise slowly if you have been sitting or lying down, to decrease dizziness.
• If you are experiencing any depression or suicidal thoughts discontinue the medicine and consult the doctor immediately.
• Your doctor may recommend regular vision checks.

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).