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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

GANCICLOVIR-500MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Gavir 500 Injection

Gavir 500 Injection belongs to the class of 'antivirals' used in the treatment of cytomegalovirus (CMV) retinitis. Cytomegalovirus (CMV) retinitis is an infection that affects the retina of the eye caused by a virus called Cytomegalovirus (CMV), especially in AIDS patients. It is a serious infection that can lead to blindness. Gavir 500 Injection is also used to prevent Cytomegalovirus disease in transplant patients who are at risk for CMV infection.

Gavir 500 Injection contains Ganciclovir, which works by killing and stopping the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis.

Gavir 500 Injection is a parenteral preparation. It will be administered by a healthcare professional; hence do not self-administer. Common side effects of Gavir 500 Injection may include nausea, vomiting, loss of appetite, itching, sensitivity to light (photosensitivity), swelling, redness and tenderness at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please inform your doctor.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have a weakened immune system, breathing problems, an electrolyte imbalance, blood disorders, and liver or kidney diseases before starting Gavir 500 Injection. Gavir 500 Injection is not recommended for use in pregnant and breastfeeding women. Hence, inform your doctor before starting Gavir 500 Injection. Avoid alcohol consumption while on treatment with Gavir 500 Injection to enable your body to fight off infections. Gavir 500 Injection should be avoided in children as the safety and efficacy are not explained.

Uses of Gavir 500 Injection

Cytomegalovirus (CMV) retinitisCytomegalovirus disease in transplant patients

Directions for Use

Gavir 500 Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Gavir 500 Injection treats viral infection of the eye caused by Cytomegalovirus (CMV) retinitis. It is also used to treat Cytomegalovirus disease in transplant patients. Gavir 500 Injection consists of Gancyclovir, an antiviral drug that works by killing and stopping the growth of the herpes simplex virus on the cornea.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gavir 500 Injection

  • Nausea
  • Vomiting
  • Photosensitivity
  • Diarrhea
  • Loss of appetite
  • Tiredness
  • Sweating
  • Redness
  • Pain
  • Injection site reactions

Drug Warnings

Inform your doctor if you are allergic to Gavir 500 Injection or any of the components in Gavir 500 Injection. It is advised to inform your doctor that you are pregnant or planning a pregnancy as Gavir 500 Injection may cause infertility problems and fetal toxicity. Patients with kidney disease should avoid receiving a name and should notify their doctor. Before beginning treatment with Gavir 500 Injection, inform your doctor if you have a history of cancer disease. Nursing mothers should avoid breastfeeding while receiving Gavir 500 Injection as it passes in breastmilk and cause side effects to infants.

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
GanciclovirAdalimumab
Severe

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
How does the drug interact with Gavir 500 Injection:
Coadministration of cidofovir with Gavir 500 Injection can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Gavir 500 Injection and Cidofovir hence it is not recommended to be taken together, but it can be taken only if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GanciclovirAdalimumab
Severe
How does the drug interact with Gavir 500 Injection:
Using Gavir 500 Injection together with adalimumab may increase the risk of serious infections.

How to manage the interaction:
Taking Gavir 500 Injection with adalimumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirClozapine
Severe
How does the drug interact with Gavir 500 Injection:
Clozapine can cause higher levels of Gavir 500 Injection in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Gavir 500 Injection and Clozapine, you can take these medicines together if prescribed by a doctor. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, weight loss, or pain, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GanciclovirCladribine
Severe
How does the drug interact with Gavir 500 Injection:
Taking cladribine together with Gavir 500 Injection may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Cladribine with Gavir 500 Injection can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GanciclovirZidovudine
Severe
How does the drug interact with Gavir 500 Injection:
Using zidovudine together with Gavir 500 Injection may increase the risk of side effects affecting the blood leading to decreased levels of blood cells.

How to manage the interaction:
Taking Gavir 500 Injection with zidovudine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, sore throat, rashes, tiredness, headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GanciclovirMaribavir
Severe
How does the drug interact with Gavir 500 Injection:
Coadministration of Gavir 500 Injection with Maribavir may alter the effectiveness of both these medications. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Maribavir and Gavir 500 Injection together can possibly result in an interaction; it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
GanciclovirEtanercept
Severe
How does the drug interact with Gavir 500 Injection:
Using Gavir 500 Injection together with etanercept may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Gavir 500 Injection and Etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.
GanciclovirGolimumab
Severe
How does the drug interact with Gavir 500 Injection:
Using Gavir 500 Injection together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Gavir 500 Injection and Golimumab, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor immediately. Do not stop using any medications without a doctor's advice.
GanciclovirDeferiprone
Severe
How does the drug interact with Gavir 500 Injection:
Gavir 500 Injection can cause higher levels of Deferiprone in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Gavir 500 Injection and Deferiprone together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms - like a sore throat, fever, or muscle aches - it's important to let a doctor know right away. Do not stop using any medications without a doctor's advice.
GanciclovirTenofovir disoproxil
Severe
How does the drug interact with Gavir 500 Injection:
coadministration of Tenofovir disoproxil with Gavir 500 Injection can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
Although taking Gavir 500 Injection and Tenofovir disoproxil together can cause an interaction, it can be taken if your doctor has suggested it. If you have symptoms like feeling sick, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat -contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Gavir 500 Injection Substitute

Substitutes safety advice
  • Cymevene 500mg Injection 1's

    by Others

    1770.75per tablet
  • NATCLOVIR 500MG VAIL INJECTION 10ML

    by Others

    137.54per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gavir 500 Injection works by killing and stopping the growth of the cytomegalovirus, thereby helping treat the infection.

Inform your doctor if you are pregnant or a nursing mother before starting treatment with Gavir 500 Injection. Maintain caution if you have kidney, liver, or blood disorders, a weakened immune system, breathing problems, and an electrolyte imbalance, as it may worsen your condition. Your doctor will administer Gavir 500 Injection only when the benefits outweigh the risks.

Please consult your doctor before you start Gavir 500 Injection if you are undergoing any immunizations/vaccinations, especially vaccines against the varicella virus.

Always inform your surgery doctor about the treatment with Gavir 500 Injection to avoid serious side effects.

No, as it is an injection, Gavir 500 Injection will be administered by the trained healthcare professional. Hence do not administer it.

Inform your doctor about any eye problems other than CMV retinitis. Do not use any medicine without consulting the doctor.

Drug-Drug Interactions Checker List

  • DIDANOSINE
  • PROBENECID
  • ZIDOVUDINE
  • CYCLOSPORINE
  • AMPHOTERICIN B
  • IMIPENEM

Special Advise

 

Disease/Condition Glossary

Cytomegalovirus (CMV) retinitis: This is an eye infection caused when Cytomegalovirus (CMV) affects the retina (light-sensing nerve layer) of the eye, which can lead to blindness. It mainly occurs in weak immune patients, such as AIDS (Acquired immune deficiency syndrome). Symptoms include eye pain, tearing, redness, blurred vision, blind spots and visual disturbances. 

Cytomegalovirus disease: It mainly occurs in people with weak immune systems. Gavir 500 Injection is used in the treatment of cytomegalovirus (CMV) disease in transplant patients.

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