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Composition :

ROSUVASTATIN-20MG

Manufacturer/Marketer :

Arion Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Genvas 20mg Tablet

Genvas 20mg Tablet belongs to the class of medicines known as statins, which reduces bad cholesterol (low-density lipoprotein-LDL) and glyceride level, thereby reducing the risk of heart attack and stroke in the future. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. 

Genvas 20mg Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. Genvas 20mg Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Genvas 20mg Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. Genvas 20mg Tablet reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.

The possible side effects of Genvas 20mg Tablet may include myalgia (muscle pain), asthenia (lack of energy), nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. Most of these side effects of Genvas 20mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is important to have your lipid profile checked regularly.

This medicine is only one part of a treatment program that should include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can normally eat while taking this medicine but avoid high-fat foods. Before starting the dose of Genvas 20mg Tablet , tell your doctor if you have kidney problems, are pregnant or breastfeeding, diabetes, severe lung disease, or musculoskeletal disorder (like myopathy and rhabdomyolysis). You should avoid taking Genvas 20mg Tablet with immune system affecting medicine (cyclosporine) or anti-HIV medicines (lopinavir, ritonavir, or atazanavir) as it might have a serious effect.

Uses of Genvas 20mg Tablet

Hyperlipidemia (high cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Sprinkle Capsule: The capsule should be consumed whole. Do not chew or crush. For patients who have trouble swallowing, open the capsule and sprinkle the contents over a small amount (tablespoon) of soft food (curd, honey, tomato ketchup, vanilla and chocolate flavour pudding) and consume it.

Medicinal Benefits

Genvas 20mg Tablet lowers the risk of cardiovascular disease and coronary events like heart attack, stroke, and heart-related chest pain (angina). Genvas 20mg Tablet is beneficial in patients who are at high risk of these events. It is also prescribed in children (aged eight years or more) suffering from familial hypercholesterolemia (a genetic disease resulting in high cholesterol) along with lipid-lowering pills and other dietary measures. Genvas 20mg Tablet plays a vital role in slowing atherosclerosis progress (blocked artery walls of heart due to fat/lipid deposition leading to heart attack and stroke) in adult patients.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Genvas 20mg Tablet

  • Myalgia (muscle pain)
  • Asthenia (lack of energy)
  • Nausea
  • Headache
  • Abdominal pain
  • Muscle pain
  • Weakness
  • Daytime drowsiness

Drug Warnings

A prolonged intake of Genvas 20mg Tablet may cause muscular disorders like myopathy and rhabdomyolysis with kidney damage. A person taking excess alcohol and affected with liver disease should consult a doctor before its intake. Caution should be exercised if you are taking any blood thinner or anticoagulants like warfarin or coumarin. At least 2 hours gap should be maintained between intake of Genvas 20mg Tablet and antacids like magnesium hydroxide and aluminium hydroxide. Increases in HbA1c and fasting glucose levels can be observed if a person regularly takes Genvas 20mg Tablet . So you should tell the doctor before having these diabetes tests. Patients with proteinuria (protein in urine) or haematuria (blood in urine) should tell the doctor before taking the Genvas 20mg Tablet , as it might require dose adjustment. It is recommended that you should have a liver enzyme test regularly if you are regularly taking Genvas 20mg Tablet .

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
AtorvastatinIndinavir
Severe

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
How does the drug interact with Genvas 20mg Tablet:
Taking Genvas 20mg Tablet with Posaconazole can increase the blood levels of Genvas 20mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Genvas 20mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinIndinavir
Severe
How does the drug interact with Genvas 20mg Tablet:
Taking Genvas 20mg Tablet with indinavir may considerably raise Genvas 20mg Tablet levels in the blood.

How to manage the interaction:
Taking Genvas 20mg Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinBoceprevir
Severe
How does the drug interact with Genvas 20mg Tablet:
Using Genvas 20mg Tablet together with boceprevir may significantly increase the blood levels of Genvas 20mg Tablet.

How to manage the interaction:
Co-administration of Genvas 20mg Tablet with Boceprevir can result in an interaction, but it can be taken if a doctor has advised it. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinItraconazole
Severe
How does the drug interact with Genvas 20mg Tablet:
Using Genvas 20mg Tablet together with itraconazole may significantly increase the blood levels of Genvas 20mg Tablet.

How to manage the interaction:
Coadministration of Genvas 20mg Tablet along with itraconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.
AtorvastatinLenalidomide
Severe
How does the drug interact with Genvas 20mg Tablet:
Coadministration of Genvas 20mg Tablet with lenalidomide can increase the risk of rhabdomyolysis (a rare condition that results in skeletal muscle tissue damage).

How to manage the interaction:
Although there is an interaction between Genvas 20mg Tablet and lenalidomide, it can be taken if a doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness accompanied by fever, dark-coloured urine, or light-coloured stools, consult a doctor immediately. breath. Do not discontinue any medications without consulting a doctor.
AtorvastatinFosamprenavir
Severe
How does the drug interact with Genvas 20mg Tablet:
Using Genvas 20mg Tablet together with fosamprenavir may significantly increase the blood levels of Genvas 20mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Genvas 20mg Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinCiclosporin
Severe
How does the drug interact with Genvas 20mg Tablet:
Taking Genvas 20mg Tablet and ciclosporin can significantly increase the blood levels of Genvas 20mg Tablet.

How to manage the interaction:
Taking Genvas 20mg Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, or yellowing of the skin or eyes, you should consult a doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinKetoconazole
Severe
How does the drug interact with Genvas 20mg Tablet:
Using Genvas 20mg Tablet with ketoconazole, may raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Genvas 20mg Tablet with ketoconazole can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.
AtorvastatinFenofibrate
Severe
How does the drug interact with Genvas 20mg Tablet:
When Genvas 20mg Tablet is used with fenofibrate, it increases the risk of side effects such as liver damage, rhabdomyolosis (uncommon illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Fenofibrate and Genvas 20mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinAtazanavir
Severe
How does the drug interact with Genvas 20mg Tablet:
Combining Genvas 20mg Tablet with atazanavir may drastically elevate Genvas 20mg Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Genvas 20mg Tablet with atazanavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ROSUVASTATIN-20MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ROSUVASTATIN-20MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consumption of Genvas 20mg Tablet with grapefruit juice may elevate Genvas 20mg Tablet levels in the blood. This can raise the chance of side effects such as liver injury and rhabdomyolysis, (an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury). Avoid the consumption of grapefruit juice along with Genvas 20mg Tablet. If you’re experiencing fever, chills, joint discomfort or swelling, unusual bleeding or bruising, skin rash, itching, lack of appetite, lethargy, nausea, vomiting, dark coloured urine, and/or yellowing of the skin or eyes, contact the doctor immediately.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products. 
  • Quitting smoking is the best strategy to lower the risk of heart disease. 
  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques. 
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Genvas 20mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Genvas 20mg Tablet works by blocking liver enzymes, causing the liver to make less cholesterol. So, Genvas 20mg Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, Genvas 20mg Tablet lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed.

No, Genvas 20mg Tablet should not be stopped even if you feel better as it lead to worsening of your condition. Please consult your doctor if you feel better and do as advised.

Genvas 20mg Tablet can cause liver damage in very rare cases, specially when alcohol is consumed along with Genvas 20mg Tablet . Caution should be taken in patients who have any underlining liver problem or history of any liver impairment and also inform your doctor before taking Genvas 20mg Tablet so that dose is adjusted accordingly.

It's unlikely that Genvas 20mg Tablet affects fertility in men or women. However there's not enough evidence to say for certain. Genvas 20mg Tablet should be avoided if your pregnant or planning for pregnancy. For best advise, consult your doctor.

Yes, taking Genvas 20mg Tablet can cause muscle aches or pains especially if you feel unwell or have a fever. Also please tell your doctor if you have a muscle weakness that is constant.

Yes, Genvas 20mg Tablet can be taken at night or any other time with or without food. It is better to take it at fixed time.

Yes, Genvas 20mg Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Genvas 20mg Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

Before starting dose of Genvas 20mg Tablet tell your doctor if you have liver/kidney problems, under active thyroid (hypothyroidism), are pregnant or breastfeeding, diabetes, severe lung disease, blood in urine (haematuria) and protein in urine (proteinuria) or musculoskeletal disorder (like myopathy and rhabdomyolysis). You should avoid taking Genvas 20mg Tablet with immune system affecting medicine (cyclosporine) or anti HIV medicines (lopinavir, ritonavir, or atazanavir) as it might have serious effect.

Usually, it is not safe to take Genvas 20mg Tablet with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Genvas 20mg Tablet along with fusidic acid.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • WARFARIN
  • CLOPIDOGREL
  • GEMFIBROZIL
  • FENOFIBRATE
  • EZETIMIBE
  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • ERYTHROMYCIN
  • FUSIDIC ACID
  • REGORAFENIB
  • RITONAVIR
  • LOPINAVIR
  • ATAZANAVIR
  • SIMEPREVIR
  • OMBITASVIR
  • PARITAPREVIR
  • DASABUVIR
  • VELPATASVIR
  • GRAZOPREVIR
  • ELBASVIR
  • GLECAPREVIR
  • PIBRENTASVIR

Special Advise

  • Your doctor may advise on regular monitoring of liver function tests to monitor the liver enzymes.

Disease/Condition Glossary

High cholesterol: There are two types of cholesterol found in our body, good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol from our body. On the other hand, excess of bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. High cholesterol known as hyperlipidaemia or dyslipidaemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol.

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