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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

PROGESTERONE-400MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gestofit 400 mg Capsule

Gestofit 400 mg Capsule belongs to the class of drugs called female hormones primarily used in combination with oestrogen for hormone replacement therapy. Besides this, Gestofit 400 mg Capsule also treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Gestofit 400 mg Capsule contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Gestofit 400 mg Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Gestofit 400 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Gestofit 400 mg Capsule or any other medicines, please tell your doctor. Avoid taking Gestofit 400 mg Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Gestofit 400 mg Capsule if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Gestofit 400 mg Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestofit 400 mg Capsule . Drive only if you are alert as Gestofit 400 mg Capsule may cause drowsiness or dizziness.

Uses of Gestofit 400 mg Capsule

Female infertility, Female hormonal imbalance

Directions for Use

Take Gestofit 400 mg Capsule as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take Gestofit 400 mg Capsule at bedtime as it may cause dizziness or drowsiness.

Medicinal Benefits

Gestofit 400 mg Capsule contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Gestofit 400 mg Capsule is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Gestofit 400 mg Capsule replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for maintenance of pregnancy, in threatened abortion and prevention of preterm labour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gestofit 400 mg Capsule

  • Dizziness
  • Drowsiness
  • Headache
  • Mood changes
  • Diarrhoea
  • Vaginal discharge
  • Joint pain
  • Hot flashes (sudden feeling of warmth) 
  • Constipation

Drug Warnings

If you are allergic to soya, Gestofit 400 mg Capsule or any other medicines, please tell your doctor. Avoid taking Gestofit 400 mg Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Gestofit 400 mg Capsule if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Gestofit 400 mg Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestofit 400 mg Capsule . Drive only if you are alert as Gestofit 400 mg Capsule may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Gestofit 400 mg Capsule . If you are about to undergo any surgery, please inform your doctor that you are taking Gestofit 400 mg Capsule .

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
ProgesteroneVenetoclax
Severe

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
How does the drug interact with Gestofit 400 Capsule:
Co-administration of Gestofit 400 Capsule with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Gestofit 400 Capsule and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneVenetoclax
Severe
How does the drug interact with Gestofit 400 Capsule:
Co-administration of Gestofit 400 Capsule with Venetoclax may greatly increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Gestofit 400 Capsule and venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience any symptoms such as nausea, vomiting, diarrhea, fatigue, or bleeding problems, and infections. Do not discontinue any medications without a doctor's advice.
ProgesteroneEdoxaban
Severe
How does the drug interact with Gestofit 400 Capsule:
When Gestofit 400 Capsule is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Gestofit 400 Capsule and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneMorphine
Severe
How does the drug interact with Gestofit 400 Capsule:
Co-administration of Gestofit 400 Capsule with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Gestofit 400 Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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PROGESTERONE-400MGCaffeine containing foods/drinks

Drug-Food Interactions

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PROGESTERONE-400MGCaffeine containing foods/drinks
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffiene and its products may interact with Gestofit 400 Capsule. Limit usage of Caffiene and its products during treatment with Gestofit 400 Capsule.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Gestofit 400 mg Capsule Substitute

Substitutes safety advice
  • Susten 400 Capsule 10's

    by Others

    61.56per tablet
  • Susten SR 400 Tablet 10's

    by Others

    71.55per tablet
  • Naturogest 400 Capsule 10's

    by Others

    66.33per tablet
  • Gestone 400 mg Capsule 10's

    by Others

    44.64per tablet
  • Gestofit 400 mg SR Tablet 10's

    by Others

    70.65per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gestofit 400 mg Capsule contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

Gestofit 400 mg Capsule may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Gestofit 400 mg Capsule and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Gestofit 400 mg Capsule reduces this risk.

You are recommended to inform your doctor that you are taking Gestofit 400 mg Capsule as you may need to stop taking Gestofit 400 mg Capsule 4 to 6 weeks before surgery to decrease the risk of blood clot.

Gestofit 400 mg Capsule may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

Gestofit 400 mg Capsule is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Gestofit 400 mg Capsule .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • RITONAVIR
  • NEVIRAPINE
  • NELFINAVIR
  • EFAVIRENZ
  • DIAZEPAM
  • SPIRONOLACTONE
  • CICLOSPORIN
  • PHENINDIONE
  • TIZANIDINE
  • TERBINAFINE
  • KETOCONAZOLE
  • GRISEOFULVIN

Special Advise

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Disease/Condition Glossary

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

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