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  3. Gibtulio Met 12.5/1000 Tablet 10's

Gibtulio Met 12.5/1000 Tablet 10's, Pack of 10 TABLETS
Gibtulio Met 12.5/1000 Tablet 10's, Pack of 10 TABLETS
Gibtulio Met 12.5/1000 Tablet 10's, Pack of 10 TABLETS
Gibtulio Met 12.5/1000 Tablet 10's, Pack of 10 TABLETS
Gibtulio Met 12.5/1000 Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Whats That

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Composition :

EMPAGLIFLOZIN-12.5MG + METFORMIN-1000MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gibtulio Met 12.5/1000 Tablet

Gibtulio Met 12.5/1000 Tablet is a combination drug that belongs to the antidiabetic class. It is primarily used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.

Gibtulio Met 12.5/1000 Tablet is composed of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin is a type of medicine known as a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low). In some cases, you may experience certain common side effects, such as frequent urination, mild skin rash or itchy skin, feeling sick (nausea), being sick (vomiting) or diarrhoea, stomach ache, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking this medication, tell your doctor or pharmacist if you are allergic to Empagliflozin and Metformin; or have other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Gibtulio Met 12.5/1000 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Gibtulio Met 12.5/1000 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Gibtulio Met 12.5/1000 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. During pregnancy/lactation, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

Uses of Gibtulio Met 12.5/1000 Tablet

Type 2 Diabetes mellitus 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Gibtulio Met 12.5/1000 Tablet is composed of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin is a type of medicine known as a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking this medication, tell your doctor or pharmacist if you are allergic to Empagliflozin and Metformin; or have other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Gibtulio Met 12.5/1000 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Gibtulio Met 12.5/1000 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Gibtulio Met 12.5/1000 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. It's generally not recommended to take empagliflozin during pregnancy/breastfeeding. Discuss the risks and benefits with your doctor. Gibtulio Met 12.5/1000 Tablet is only for adults (from 18 years). It is not recommended for anyone aged 85 years or older.

Drug-Drug Interactions

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EmpagliflozinGatifloxacin
Critical
MetforminIopamidol
Critical

Drug-Drug Interactions

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EmpagliflozinGatifloxacin
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Coadministration of Gibtulio Met 12.5/1000 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
It is not recommended to take Gibtulio Met 12.5/1000 Tablet with Gatifloxacinas it can result in an interaction, but it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medication without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iopamidol with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iopromide with Gibtulio Met 12.5/1000 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Gibtulio Met 12.5/1000 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iopanoic acid with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iodixanol with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iotroxic acid with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Ioglycamic acid with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iopentol with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Gibtulio Met 12.5/1000 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Gibtulio Met 12.5/1000 Tablet:
Co-administration of Iofendylate with Gibtulio Met 12.5/1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gibtulio Met 12.5/1000 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Gibtulio Met 12.5/1000 Tablet more than once per day. Do not use other over-the-counter medicines, herbal or vitamin supplements without informing your pharmacist or doctor when you take Gibtulio Met 12.5/1000 Tablet .
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include reducing sugars and fatty foods and avoiding carbonated drinks and foods that cause gas.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Gibtulio Met 12.5/1000 Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gibtulio Met 12.5/1000 Tablet is composed of two antidiabetic medicines, namely: Empagliflozin and Metformin. Empagliflozin works by increasing the amount of sugar that leaves your body in your pee. Metformin lowers your blood sugar levels by improving the way your body handles insulin. Altogether, they lower blood glucose more effectively.

Your doctor may advise Gibtulio Met 12.5/1000 Tablet with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to control blood sugar levels while using Gibtulio Met 12.5/1000 Tablet with or without other antidiabetic drugs.

It is not recommended to use Gibtulio Met 12.5/1000 Tablet along with diuretics. Simultaneous use of Gibtulio Met 12.5/1000 Tablet with diuretics can cause dehydration, and may these can increase your risk of dehydration and lower your blood pressure.

Diabetes is normally treated for the rest of one's life. Do not discontinue taking Gibtulio Met 12.5/1000 Tablet pills without first consulting your doctor.

It is safe to take empagliflozin for a long time. There is no proof that this medication is harmful to your overall health.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • PREDNISOLONE
  • FUROSEMIDE
  • BACLOFEN
  • INSULIN
  • GLICLAZIDE

Special Advise

  • It is advised to monitor your blood sugar levels regularly.
  • If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Gibtulio Met 12.5/1000 Tablet temporarily.
  • Regular monitoring of kidney functioning is advised while using Gibtulio Met 12.5/1000 Tablet .
  • Gibtulio Met 12.5/1000 Tablet may make you test positive for a urine glucose test. Hence inform your doctor in advance that you take Gibtulio Met 12.5/1000 Tablet .

Disease/Condition Glossary

Type 2 diabetes: Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It can cause symptoms like excessive thirst, needing to pee a lot and tiredness. It can also increase your risk of getting serious problems with your eyes, heart and nerves. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups. It's caused by problems with a chemical in the body (hormone) called insulin. It's often linked to being overweight or inactive or having a family history of type 2 diabetes.

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