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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
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Composition :

LEVOFLOXACIN-500MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Glevo I.V 100ml

Glevo I.V 100ml belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Glevo I.V 100ml is composed of 'Levofloxacin' that belongs to a class of quinolone antibiotics. It works by inhibiting an enzyme called gyrase, responsible for the growth and development of bacterial DNA. Thereby, inhibits bacterial growth and treats bacterial infection.

Glevo I.V 100ml will be administered by a healthcare professional. Glevo I.V 100ml may cause a few side effects, although not everybody gets them. Common side effects of Glevo I.V 100ml include constipation, nausea, diarrhoea, headache, dizziness, light-headedness, trouble sleeping/insomnia, pain, redness, and swelling at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have any allergic reactions to medicines, liver/kidney problems, fits, diabetes, tendonitis (inflammation of the tendon, a tissue connecting muscle and bone), myasthenia gravis (muscular weakness), high blood pressure, low blood potassium (hypokalaemia), and mood disorders. Glevo I.V 100ml should be used only with a doctor's advice during pregnancy and breastfeeding. Glevo I.V 100ml may cause light-headedness/dizziness; in such cases, please do not drive until you are alert. Glevo I.V 100ml may cause dizziness; hence avoid or limit alcohol consumption.

Uses of Glevo I.V 100ml

Bacterial infections.

Directions for Use

Glevo I.V 100ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Glevo I.V 100ml treats various bacterial infections, including infections of the lower respiratory tract (lungs), urinary tract (kidneys and bladder), skin, soft tissues, and prostate gland. It contains Levofloxacin, a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for the replication, transcription, and repair of the DNA. Thereby, inhibits bacterial growth and treats bacterial infection. It is also used to treat anthrax (a rare but serious bacterial illness) and certain types of plague.

Storage

Store in a cool and dry place away from sunlight
Side effects of Glevo I.V 100ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Drug Warnings

Brief your medical history to the doctor if you are allergic to any of the components in Glevo I.V 100ml. Let your doctor know if you have any allergic reactions to medicines, liver/kidney diseases, diabetes, fits, tendon problems, high blood pressure, hypokalaemia, and mood disorders before starting Glevo I.V 100ml. Glevo I.V 100ml can make myasthenia gravis worse; hence you should take Glevo I.V 100ml only under a doctor's supervision. Inform your doctor if you are pregnant or breastfeeding before starting this medicine. Glevo I.V 100ml may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol consumption to prevent any undesired effects like dizziness while undergoing treatment.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Glevo I.V 100ml:
Taking Glevo I.V 100ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Glevo I.V 100ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Glevo I.V 100ml:
The combination of Amiodarone and Glevo I.V 100ml may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Glevo I.V 100ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Glevo I.V 100ml:
Using sotalol together with Glevo I.V 100ml can increase the risk of an irregular heart rhythm that may be serious. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Glevo I.V 100ml with Sotalol is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Glevo I.V 100ml:
Combining Glevo I.V 100ml with Disopyramide can increase the risk of irregular heart rhythm .

How to manage the interaction:
Taking Glevo I.V 100ml with Disopyramide is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Glevo I.V 100ml:
Using chloroquine together with Glevo I.V 100ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Glevo I.V 100ml and chloroquine together can result in an interaction, it can be taken if a doctor has advised it. However, contact the doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Glevo I.V 100ml:
Although it is a very rare adverse effect, taking Glevo I.V 100ml with crizotinib increases the risk of an abnormal heart rhythm. If you're dealing with other heart illnesses, electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
Concomitant administration of Glevo I.V 100ml with crizotinib can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Glevo I.V 100ml:
when Glevo I.V 100ml is taken along with Insulin detemir, it can affect blood glucose levels. They may cause hyperglycemia (high blood glucose) and, less commonly, hypoglycemia (low blood glucose).

How to manage the interaction:
Although taking Glevo I.V 100ml and Insulin detemir together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor, if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, sweat, palpitations, and rapid heartbeat, increased-hunger, thirst, and urine. It is recommended to maintain blood glucose levels. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Glevo I.V 100ml:
Taking Glevo I.V 100ml with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Glevo I.V 100ml with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Glevo I.V 100ml:
Using arsenic trioxide together with Glevo I.V 100ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Glevo I.V 100ml with Arsenic trioxide together can result in an interaction, but it can be taken if a doctor has advised it. If you experience any symptoms like an irregular heart rhythm, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, having trouble breathing, or feeling your heart beating fast or irregularly, you should call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Glevo I.V 100ml:
Coadministration of Glevo I.V 100ml and Hydrocortisone can induce tendinitis (inflammation of the thick fibrous cords that attach muscle to bone. These cords are called tendons) and tendon rupture.

How to manage the interaction:
Concomitant administration of Glevo I.V 100ml with hydrocortisone can result in an interaction, it can be taken if a doctor has advised it. If you experience pain, swelling, or inflammation in a tendon location such as the back of the ankle, shoulder, biceps, hand, or thumb, call a doctor immediately. You should refrain from exercising or using the afflicted region.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Glevo I.V 100ml is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.

Glevo I.V 100ml should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver or kidney diseases, hypokalaemia, diabetes, joint or tendon problems (tendonitis, bursitis), mood disorders (depression), myasthenia gravis (muscle weakness), peripheral neuropathy (nerve damage), fits, aneurysm (weakening of an artery), blockage of the aorta or other blood vessels, high blood pressure, and connective tissue disorders like Marfan syndrome and Ehlers-Danlos syndrome.

Glevo I.V 100ml may cause hypoglycemia (low blood sugar levels) or hyperglycemia (high blood sugar levels). Inform your doctor if you have diabetes and monitor your blood sugar levels regularly if prescribed.

Glevo I.V 100ml can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Glevo I.V 100ml if you are undergoing any vaccinations.

Antacids and multivitamins with minerals can decrease the efficacy of Glevo I.V 100ml. Hence, it is recommended to take Glevo I.V 100ml 2 to 4 hours before or 4 to 6 hours after taking magnesium/aluminium antacids, sucralfate, zinc or iron preparations, and multivitamins with minerals.

Diarrhoea can be a side-effect of Glevo I.V 100ml. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Glevo I.V 100ml. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Glevo I.V 100ml therapy.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • AZITHROMYCIN
  • WARFARIN
  • THEOPHYLLINE
  • CYCLOSPORINE
  • DIGOXIN
  • PROBENECID
  • CIMETIDINE
  • QUINIDINE
  • AMITRIPTYLINE

Special Advise

  • Glevo I.V 100ml can cause serious tendon problems and nerve damage; hence you should be cautious. If you experience any symptoms like severe headaches, extreme hunger, irritability, numbness, tingling, burning pain, confusion, agitation, and memory problems, please stop using this medicine and seek immediate medical advice.
  • Glevo I.V 100ml might produce false-positive urine screening results for opiates. Inform the laboratory staff that you are taking Glevo I.V 100ml if you are due to undergo any tests. 
  • Glevo I.V 100ml may cause mental health-related side effects; hence patients with mood disorders should take advice accordingly.
  • If you are diabetic, monitor your blood sugar levels regularly since Glevo I.V 100ml may affect blood glucose levels.
  • Quinolone antibiotics like Levofloxacin may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) in electrocardiogram (ECG) in some patients.
  • Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics. Please consult your doctor if you experience prolonged diarrhoea.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have a thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, shortness of breath, chills, muscle pain, fatigue, and tiredness. Untreated bacterial infections may lead to serious life-threatening conditions like sepsis.

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