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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gluconorm PG 2 Tablet

Gluconorm PG 2 Tablet belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (metabolizes glucose), or if produced, it cannot function properly in the body.

Gluconorm PG 2 Tablet is a combination of three medicines, namely: Metformin, Glimepiride, and Pioglitazone. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the amount of insulin released by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and also by improving the sensitivity of tissues towards insulin effects.

You should take this medicine as prescribed by your doctor. You may experience side-effects of such as nausea (feeling sick), vomiting (falling sick), diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Some patients experience decline in blood sugar levels lower than normal (hypoglycemia) resulting in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability, and weakness. In such cases, seek medical attention immediately.

Do not take Gluconorm PG 2 Tablet if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). Gluconorm PG 2 Tablet may cause ‘lactic acidosis’ (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Gluconorm PG 2 Tablet

Type 2 Diabetes Mellitus

Directions for Use

Gluconorm PG 2 Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Gluconorm PG 2 Tablet contains Metformin, Glimepiride, and Pioglitazone. Gluconorm PG 2 Tablet is given when single or dual therapy of hypoglycemic agents is not effective in diabetes patients. Metformin acts by decreasing liver glucose production and intestinal glucose uptake.  Glimepiride acts by increasing the secretion of insulin by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and improving insulin sensitivity in muscle and fat. 

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Gluconorm PG 2 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Drug Warnings

Gluconorm PG 2 Tablet should be used with caution in patients with heart diseases as it increases the risk of heart failure. Gluconorm PG 2 Tablet may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Do not consume excess alcohol as it increases the risk of lactic acidosis.  Gluconorm PG 2 Tablet may lower vitamin B12 levels, so it is recommended to take blood tests regularly to identify any vitamin deficiencies.

Drug-Drug Interactions

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MetforminIopamidol
Critical
MetforminIoglycamic acid
Critical

Drug-Drug Interactions

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MetforminIopamidol
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iopamidol with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Ioglycamic acid with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iohexol with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iopromide with Gluconorm PG 2 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Gluconorm PG 2 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIocarmic acid
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Gluconorm PG 2 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iodixanol with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIofendylate
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iofendylate with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Gluconorm PG 2 Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iopydol with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Gluconorm PG 2 Tablet:
Co-administration of Iopentol with Gluconorm PG 2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Gluconorm PG 2 Tablet with Iopentol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing foods with whole grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of heart diseases in diabetes patients.

Side Effects of Gluconorm PG 2 Tablet

  • Nausea (feeling sick)
  • Vomiting (falling sick)
  • Diarrhea
  • Headache
  • Stomach ache
  • Respiratory infection
  • Weight gain
  • Sweating
  • Palpitations
  • Numbness
  • Vision problems

Habit Forming

No

Therapeutic Class

ANTIDIABETICS AND ANTIHYPERGLYCEMICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gluconorm PG 2 Tablet is a combination of three antidiabetic medicines, Metformin, Glimepiride, and Pioglitazone. It works by increasing insulin production, helping to restore your body's appropriate response to insulin, especially muscle and fatty tissues, thereby lowering your elevated blood sugar levels.

Patients with type 2 diabetes who have congestive heart failure, kidney problems, liver problems, vision problems, or diabetic ketoacidosis should not take Gluconorm PG 2 Tablet . It is also not given to pregnant, breastfeeding, or a premenopausal woman.

Hypoglycemia refers to low blood glucose levels. Gluconorm PG 2 Tablet may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, intense exercise, or take other antidiabetic medicine along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.

If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. So, it is always advised to carry glucose tablets or sugar candies with you.

Yes, type 2 diabetes may also occur in children. The risk increases if the child is overweight or obese.

You may experience high blood sugar, symptoms such as increased thirst and hunger, frequent urination, weight loss, delayed wound healing, and frequent infections. Consult a doctor or endocrinologist to confirm the diagnosis.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • TETRACYCLINE
  • CLARITHROMYCIN
  • FLUCONAZOLE
  • PROBENECID

Special Advise

  • Gluconorm PG 2 Tablet shows optimum effects when you follow healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.
  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice.
  • Take short frequent meals, avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce intake of carbohydrate-rich food like potato, rice, mangoes, bread, sugar, etc.

Disease/Condition Glossary

Type 2 diabetes mellitus: It is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin, or in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite, and dry mouth. This condition may worsen over time and cause toxic effects if not properly treated.

Have a query?

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Alcohol

Caution

Alcohol may increase the risk of side-effects and worsen the condition.

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Pregnancy

Unsafe

Gluconorm PG 2 Tablet is a category C drug and may cause harmful effects to the unborn baby. So, it is used only when the benefits of this medicine outweigh the risks.

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Breast Feeding

Unsafe

Gluconorm PG 2 Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

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Driving

Caution

Gluconorm PG 2 Tablet may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using Gluconorm PG 2 Tablet .

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Liver

Caution

Gluconorm PG 2 Tablet should be taken with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Gluconorm PG 2 Tablet should be taken with caution especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Gluconorm PG 2 Tablet is not recommended for use in children below 18 years of age.

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