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Prescription drugWhats That
Synonym :
GLIMEPIRIDE+METFORMIN HYDROCHLORIDE
Composition :
GLIMEPIRIDE-2MG + METFORMIN-1000MG
Manufacturer/Marketer :
Alkem Laboratories Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
GlimepirideMoxifloxacin
Severe
GlimepirideBumetanide
Severe
Drug-Drug Interactions
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GlimepirideMoxifloxacin
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Co-administration of Moxifloxacin can affect blood glucose levels. Both high blood glucose and low blood glucose.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience headache, dizziness, rapid heartbeat, increased thirst, and increased urination. Do not discontinue the medications without consulting a doctor.
Co-administration of Moxifloxacin can affect blood glucose levels. Both high blood glucose and low blood glucose.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience headache, dizziness, rapid heartbeat, increased thirst, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideBumetanide
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
GlimepirideLeflunomide
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Leflunomide may increase the blood levels and effects of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideDiethylstilbestrol
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Co-administration of Diethylstilbestrol may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction between Glucoryl-M 2 Forte Tablet and Diethylstilbestrol, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Diethylstilbestrol may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although there is a possible interaction between Glucoryl-M 2 Forte Tablet and Diethylstilbestrol, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideAminolevulinic acid
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Aminolevulinic acid sensitizes your skin to bright lights and combining it with other medications that can also have this effect (i.e., photosensitivity) such as Glucoryl-M 2 Forte Tablet may increase the risk of a severe sunburn.
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Aminolevulinic acid sensitizes your skin to bright lights and combining it with other medications that can also have this effect (i.e., photosensitivity) such as Glucoryl-M 2 Forte Tablet may increase the risk of a severe sunburn.
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
GlimepirideCitalopram
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Taking Glucoryl-M 2 Forte Tablet with Citalopram may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Glucoryl-M 2 Forte Tablet with Citalopram may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Glucoryl-M 2 Forte Tablet can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideTrovafloxacin
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
When Glucoryl-M 2 Forte Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
When Glucoryl-M 2 Forte Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
GlimepirideEnoxacin
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Taking Glucoryl-M 2 Forte Tablet with Enoxacin, may affect blood glucose levels which may lead to hypoglycemia (low blood glucose) and hyperglycemia (high blood glucose).
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Enoxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. This can be a good thing if you need help lowering your blood sugar, but it can also be a problem if it goes too low. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Taking Glucoryl-M 2 Forte Tablet with Enoxacin, may affect blood glucose levels which may lead to hypoglycemia (low blood glucose) and hyperglycemia (high blood glucose).
How to manage the interaction:
Taking Glucoryl-M 2 Forte Tablet with Enoxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. This can be a good thing if you need help lowering your blood sugar, but it can also be a problem if it goes too low. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideBisoprolol
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Concomitant use of bisoprolol with Glucoryl-M 2 Forte Tablet may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.
How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Glucoryl-M 2 Forte Tablet if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
Concomitant use of bisoprolol with Glucoryl-M 2 Forte Tablet may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.
How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Glucoryl-M 2 Forte Tablet if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
GlimepirideAmprenavir
Severe
How does the drug interact with Glucoryl-M 2 Forte Tablet:
Co-administration of Amprenavir and Glucoryl-M 2 Forte Tablet may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although taking Glucoryl-M 2 Forte Tablet and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of Amprenavir and Glucoryl-M 2 Forte Tablet may interfere with blood glucose control and reduce the effectiveness of Glucoryl-M 2 Forte Tablet.
How to manage the interaction:
Although taking Glucoryl-M 2 Forte Tablet and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Glucoryl-M 2 Forte Tablet Substitute
Amaryl M Forte 2 mg Tablet 15's
by AYUR
₹18.21per tabletGlycomet-GP 2 Forte Tablet 10's
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₹10.31per tabletGluconorm G2 Forte Tablet 15's
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₹16.47per tabletGemer DS 2 Tablet 15's
by Others
₹13.50per tabletZoryl M 2 Forte Tablet 15's
by Others
₹15.49per tablet
Product Substitutes
Author Details
Drug-Diseases Interactions
GLIMEPIRIDE-2MG+METFORMIN-1000MGHypertensive heart and renal disease
Severe
GLIMEPIRIDE-2MG+METFORMIN-1000MGUnspecified kidney failure
Severe
Drug-Diseases Interactions
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GLIMEPIRIDE-2MG+METFORMIN-1000MGHypertensive heart and renal disease
Severe
How does the disease interact with Glucoryl-M 2 Forte Tablet:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-2MG+METFORMIN-1000MGUnspecified kidney failure
Severe
How does the disease interact with Glucoryl-M 2 Forte Tablet:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-2MG+METFORMIN-1000MGOther disorders of adrenal gland
Moderate
How does the disease interact with Glucoryl-M 2 Forte Tablet:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-2MG+METFORMIN-1000MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Glucoryl-M 2 Forte Tablet:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-2MG+METFORMIN-1000MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Glucoryl-M 2 Forte Tablet:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
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