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Written By Sunny S , MBBS
Reviewed By Hari Kumar , MBBS
Non returnable*
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Synonym :

METFORMIN HYDROCHLORIDE

Composition :

METFORMIN-500MG

Manufacturer/Marketer :

USV Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

Glycomet-500 SR Tablet belongs to a group of anti-diabetic medicines called biguanides used in the treatment of diabetes. It helps to lower the increased blood glucose level in type 2 diabetes patients. Type 2 diabetes is a chronic or lifelong disorder that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.

Glycomet-500 SR Tablet is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes. Glycomet-500 SR Tablet restores the body's response to insulin, decreases the amount of blood sugar produced by the liver, and delays the absorption of sugar by the stomach or intestines. Besides, Glycomet-500 SR Tablet has off-label usage in women with polycystic ovary syndrome (PCOS) where it helps normalize the menstruation cycle by restoring the body's hormonal balance, lowers blood sugar levels, and stimulates ovulation. 

Usually, Glycomet-500 SR Tablet does not cause very significant side effects. Common side effects include diarrhoea, nausea, vomiting, or a metallic taste in the mouth. In very rare cases, it may cause a condition known as lactic acidosis (too much lactic acid in the body) with symptoms like dizziness, drowsiness, muscle pain, etc. Your sugar level may go down while taking this medicine with heavy exercise, drinking excessive alcohol, or skipping meals. Talk to the doctor about any of the health conditions listed above that may require urgent medical treatment.

Glycomet-500 SR Tablet works best when coupled with a healthy lifestyle like losing weight if you are overweight (BMI >25), eating fewer calories (low fat and sugary food), and being more physically active (at least 150 min of activity every week).

Type 2 diabetes mellitus
Glycomet-500 SR Tablet should not be used unless prescribed by a doctor. Glycomet-500 SR Tablet should be taken with meals to help reduce stomach or bowel side effects or as directed by your doctor. Your doctor will advise you how often you take your tablets on the basis of your medical condition. Swallow Glycomet-500 SR Tablet with a full glass of water.

Glycomet-500 SR Tablet plays a vital role in managing diabetes and achieving good control of blood sugar levels by delaying the absorption of sugar and increasing insulin sensitivity in the body. Glycomet-500 SR Tablet does not cause a sudden lowering of the blood glucose level or cause significant hypoglycaemia. Unlike other anti-diabetic therapies like sulfonylureas or insulin, Glycomet-500 SR Tablet does not cause weight gain but may cause modest weight loss. In the prediabetic condition, Glycomet-500 SR Tablet is the only recommended treatment available. Glycomet-500 SR Tablet also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of foot! Glycomet-500 SR Tablet also helps to reduce your chance of having a heart attack or stroke. 

Store in a cool and dry place away from sunlight

Side Effects of Glycomet-500 SR Tablet

  • Digestive problems
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Loss of appetite

Some diabetic patients taking Glycomet-500 SR Tablet may develop a serious condition called lactic acidosis. In lactic acidosis, there is too much lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required for the elimination of excess lactic acid from the blood. You should not take metformin if you have kidney disease, as measured by a blood test. Glycomet-500 SR Tablet may lower vitamin B-12 levels, so try to have blood test annual blood and vitamin. Glycomet-500 SR Tablet , when used with insulin, may extremely lower the blood sugar level. So, the doctor may lower the dose of insulin.

Drug-Drug Interactions

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MetforminIopamidol
Critical
MetforminIoxitalamic acid
Critical

Drug-Drug Interactions

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MetforminIopamidol
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Iopamidol with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoxitalamic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Glycomet-500 SR Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Glycomet-500 SR Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIofendylate
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Iofendylate with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Iotroxic acid with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIocarmic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Glycomet-500 SR Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Glycomet-500 SR Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIoglicic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Ioglicic acid with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Iopanoic acid with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Glycomet-500 SR Tablet:
Co-administration of Ioglycamic acid with Glycomet-500 SR Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Glycomet-500 SR Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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  • Invest at least 150 min of your week in moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week. 
  • Losing weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replacing refined carbohydrates-containing foods with whole grain foods and increasing intake of fruits and veggies and other fiber enriched foods. 
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil. 
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes or meditation or yoga.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, cheese, etc.). 
  • Keep your blood pressure as normal (140/90) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.
No
ANTIDIABETICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Yes, Glycomet-500 SR Tablet can cause the minor upset of stomach. However, do not stop taking it. Discuss with your doctor in case of severe stomach upset.

Yes, initial treatment with Glycomet-500 SR Tablet is known to cause weight loss. However, if you experience excessive weight loss while on treatment with Glycomet-500 SR Tablet , inform your doctor without any delay. There is a possibility that your dosage needs to be adjusted.

Usually taking Glycomet-500 SR Tablet does not cause constipation. However, some people may experience flatulence, stomach pain and constipation while on Glycomet-500 SR Tablet . In case you experience discomfort, speak with your doctor.

Yes. If you are taking Insulin regularly you need to consult Doctor before taking Metformin.

If you forget to take Glycomet-500 SR Tablet , do NOT take a double dose to make up for your forgotten dose. Taking overdose might cause your sugar level to fall down rapidly. Try to take the next dose at the usual time.

Do not take excessive alcohol while taking Metformin, as this may increase the risk of a life-threatening condition called as lactic acidosis (too much of lactic acid in the body) which causes symptoms like dizziness, drowsiness, muscle pain, fast, shallow breathing etc.

Contact your doctor before having an X-ray or scan which involves the use of the injection of contrast materials that contain iodine into your bloodstream as it may affect your kidney function.

Your doctor will decide when you must stop and when to restart your treatment with Glycomet-500 SR Tablet before and after the surgery.

No. Metformin is only prescribed for the treatment of type 2 diabetes also called as 'non-insulin-dependent diabetes'.

Drug-Drug Interactions Checker List

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  • Keep taking Glycomet-500 SR Tablet  even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice. 
  • Take short frequent meals, avoid prolonged fasting when taking Glycomet-500 SR Tablet . Beware of symptoms of hypoglycaemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience any of the above mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also get in touch with your physician. Make sure to carry these with you at all times, especially during long travels. 
  • It is always better that your physician knows about any underlying conditions like kidney disease or liver disease, prior heart attack, alcohol intake, etc before the doctor prescribes you Glycomet-500 SR Tablet .
  • Avoid drinking alcohol while on Glycomet-500 SR Tablet  as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce intake of carbohydrate rich food like potato, rice, mangoes, bread, sugar etc.
  • Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

Type 2 diabetes: It is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase chance of heart attack or stroke.

Side effects of Glycomet-500 SR Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
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