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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Psychocare Health Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Gnpn-NT Tablet 10's

Gnpn-NT Tablet 10's is a combination medicine indicated for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Gnpn-NT Tablet 10's contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, and tingling sensations. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Gnpn-NT Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Gnpn-NT Tablet 10's should not be given to children unless prescribed by the doctor. Avoid consuming alcohol along with Gnpn-NT Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Gnpn-NT Tablet 10's

Neuropathic pain

Directions for Use

Take Gnpn-NT Tablet 10's with or without food. Swallow Gnpn-NT Tablet 10's as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Gnpn-NT Tablet 10's is used to treat neuropathic pain. Gnpn-NT Tablet 10's is a combination of two drugs: Gabapentin and Nortriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Nortriptyline belongs to tricyclic antidepressants. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Nortriptyline works by preventing the released chemical messenger in brains (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain and prevents the movement of pain signals in the brain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gnpn-NT Tablet 10's

  • Dizziness
  • Sleepiness
  • Tiredness
  • Headache
  • Nausea
  • Vomiting
  • Blurred vision
  • Dry mouth

Drug Warnings

Do not take Gnpn-NT Tablet 10's if you are allergic to any of its contents. Inform your doctor before taking Gnpn-NT Tablet 10's if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Gnpn-NT Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Gnpn-NT Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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NortriptylineTranylcypromine
Critical
NortriptylinePotassium citrate
Critical

Drug-Drug Interactions

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NortriptylineTranylcypromine
Critical
How does the drug interact with Gnpn-NT Tablet:
Coadministration of Gnpn-NT Tablet with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Gnpn-NT Tablet with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Gnpn-NT Tablet:
Coadministration of Gnpn-NT Tablet with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Gnpn-NT Tablet with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NortriptylineSelegiline
Critical
How does the drug interact with Gnpn-NT Tablet:
Co-administration of Gnpn-NT Tablet with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Gnpn-NT Tablet with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineZiprasidone
Critical
How does the drug interact with Gnpn-NT Tablet:
Coadministration of Gnpn-NT Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Gnpn-NT Tablet with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
NortriptylineSafinamide
Critical
How does the drug interact with Gnpn-NT Tablet:
Coadministration of Gnpn-NT Tablet with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Gnpn-NT Tablet with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Gnpn-NT Tablet:
Using Gnpn-NT Tablet together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Gnpn-NT Tablet is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
NortriptylineLinezolid
Critical
How does the drug interact with Gnpn-NT Tablet:
Coadministration of Gnpn-NT Tablet with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Gnpn-NT Tablet with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NortriptylineClonidine
Severe
How does the drug interact with Gnpn-NT Tablet:
Co-administration of Clonidine and Gnpn-NT Tablet may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Gnpn-NT Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact a doctor. Do not discontinue any medications without consulting a doctor.
NortriptylineNorepinephrine
Severe
How does the drug interact with Gnpn-NT Tablet:
Gnpn-NT Tablet can enhance the effects of Norepinephrine on blood pressure.

How to manage the interaction:
Although taking Norepinephrine and Gnpn-NT Tablet together can cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your blood pressure regularly. Do not stop using any medications without a doctor's advice.
NortriptylineBupropion
Severe
How does the drug interact with Gnpn-NT Tablet:
Taking bupropion with Gnpn-NT Tablet may raise the chance of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Gnpn-NT Tablet can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet, as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Gnpn-NT Tablet 10's Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gnpn-NT Tablet 10's contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

To treat your condition effectually, continue taking Gnpn-NT Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Gnpn-NT Tablet 10's; your doctor will reduce the dose gradually.

Gnpn-NT Tablet 10's may cause dry mouth. In that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Gnpn-NT Tablet 10's helps in the treatment of diabetic neuropathy (nerve damage in diabetic patients). However, please consult your doctor before starting Gnpn-NT Tablet 10's if you have diabetes.

Drug-Drug Interactions Checker List

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  • METHADONE

Special Advise

  • If you are taking any antacids containing aluminum or magnesium, try to keep at least 2 hours gap between intake of Gnpn-NT Tablet 10's and these antacids to avoid drug-drug interaction.
  • Gnpn-NT Tablet 10's can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position

 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease caused due to damage of sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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