Grandem-1 Tablet 10's

Grandem-1 Tablet 10's belongs to the class of ‘anti-emetic’ drugs, primarily used to treat nausea and vomiting caused by medical treatments, such as chemotherapy or radiation treatment for cancer, etc. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Grandem-1 Tablet 10's contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron' that belongs to the class of serotonin receptor antagonists or serotonin blockers. It works by blocking the activity of serotonin (chemical messenger) in the brain that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Grandem-1 Tablet 10's include diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, drowsiness, trouble sleeping , and anxiety. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Grandem-1 Tablet 10's. Let your doctor know if you have any liver, kidney, or heart diseases, stomach/intestinal problems, allergic reactions , and low levels of potassium and magnesium in the blood before starting Grandem-1 Tablet 10's. Grandem-1 Tablet 10's may make you dizzy or drowsy, hence avoid driving if you are not mentally alert. Consult your doctor before taking Grandem-1 Tablet 10's if you are pregnant, planning for pregnancy, or breastfeeding. Avoid consuming alcohol along with Grandem-1 Tablet 10's as it could lead to increased drowsiness. 

Grandem-1 Tablet 10's contains an anti-emetic drug, 'Granisetron' that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery, etc. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Grandem-1 Tablet 10's works by blocking the activity of serotonin in the brain and preventing post-operative nausea and vomiting.

• Diarrhoea
• Constipation
• Stomach pain
• Weakness
• Headache
• Fever
• Dizziness
• Drowsiness
• Trouble sleeping
• Anxiety

Grandem-1 Tablet 10's may cause serotonin syndrome/toxicity when used with other drugs like ecstasy (MDMA) and antidepressants. Hence it is suggested to seek medical advice if you are using any prescription or non-prescription medicines. Inform your doctor if you have a history of stomach/intestinal problems like stomach ache, wind, feeling or being sick, and difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Grandem-1 Tablet 10's. Please consult your doctor if you are pregnant or breastfeeding if the doctor has advised you Grandem-1 Tablet 10's. Grandem-1 Tablet 10's may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol as it could lead to increased dizziness. Grandem-1 Tablet 10's is not recommended in children below two years of age.

Drug-Drug Interaction: Grandem-1 Tablet 10's may interact with antidepressants (lithium, duloxetine), heart-related drugs (amiodarone, quinidine), antipsychotic drugs (pimozide), HIV/AIDS drugs (ritonavir), antibiotics (erythromycin) and St. John's wort, a plant-based medicine used for depression and mood disorders.

Drug-Food Interaction: Avoid alcohol consumption while being treated with Grandem-1 Tablet 10's to prevent adverse effects.

Drug-Disease Interaction: Before using Grandem-1 Tablet 10's, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick or difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), liver or kidney diseases.

• LITHIUM
• DULOXETINE
• AMIODARONE
• QUINIDINE
• RITONAVIR
• ERYTHROMYCIN

• Avoid chocolates, junk food, cheese, processed food, alcohol and smoking.
• You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy and stress reduction techniques.
• Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
• Include a diet rich in whole grains, vegetables and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
• You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon balm.
• Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Let your doctor know that you are taking Grandem-1 Tablet 10's if you are undergoing any medical tests.

Nausea is defined as stomach discomfort and the sensation of an urge to vomit. It is a precursor to vomiting. It is not a painful symptom but can cause discomfort in the chest, upper abdomen or back of the throat. Nausea can be triggered by various factors like motion from a car and plane, taking pills on an empty stomach, eating too much or too little and drinking excessive amounts of alcohol.

Vomiting or throwing up is the forcible voluntary or involuntary emptying of the stomach contents through the mouth. Vomiting can also occur without having any underlying diseases in conditions like pregnancy, hangover, overeating and motion sickness. Nausea or vomiting may be triggered by many factors, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer or bulimia (eating disorder).