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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
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Composition :

DIMENHYDRINATE-50MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gravol Tablet

Gravol Tablet belongs to the class of medications called ‘antihistamines’ used to prevent and treat nausea (feeling sick), vomiting (being sick), and dizziness caused by motion sickness. Besides this, it also used to treat nausea and vomiting associated with radiation sickness, surgery, drug-induced, Meniere disease (feelings of spinning and inner ear problems). Motion sickness is an illness caused by motion during travel characterized by nausea and vomiting.

 

Gravol Tablet contains ‘Dimenhydrinate’, which acts as an antihistamine and anticholinergic. It blocks the muscarinic cholinergic receptor (M1) in the brain, thereby producing a calming and anti-nausea effect. It is also used to treat symptoms of other motion and balance problems, such as feelings of spinning and inner ear problems (Meniere's disease).

 

Gravol Tablet may cause side effects like dry mouth, blurred vision, drowsiness, dizziness, headache, tiredness, disorientation,  tinnitus, dry mouth, palpitation, and low blood pressure (hypotension). Most of these side effects do not require medical attention and resolve gradually over time. However, seek medical attention immediately if these side effects persist or worsen.

 

Notify your doctor if you have breathing problems (asthma, emphysema), high pressure in the eye (glaucoma), seizures (fits), liver, kidney, heart problems, chronic obstructive pulmonary disease (COPD) or sleep apnea (sleeping disorder). Consult your doctor if you are pregnant or breastfeeding. Gravol Tablet should not be given to children below 2 years as the safety and effectiveness were not established. Gravol Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Uses of Gravol Tablet

Motion sickness

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break the tablet/capsule.Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.Syrup/Suspension/Drops: Shake the pack well before use. Take the prescribed dose by mouth using a measuring cup/dosing syringe/dropper.

Medicinal Benefits

Gravol Tablet contains ‘Dimenhydrinate’, which belongs to the class of ‘antihistamine’. Gravol Tablet also has anticholinergic properties. It works by blocking the muscarinic cholinergic receptor (M1) in the brain, thereby, preventing nausea and vomiting. Gravol Tablet used to prevent nausea and vomiting associated with conditions like travel or motion sickness, radiation sickness, postoperative, drug-induced, Meniere disease (feeling of spinning and inner ear problems) in adults.

Storage

Store in a cool and dry place away from sunlight
Side effects of Gravol Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Perform balance exercises like heel raises, standing on one leg, and weight shifts with the guidance of a physical therapist.
  • Focus on strengthening leg muscles and core muscles for better stability.
  • Stay hydrated by drinking plenty of water as dehydration may lead to unsteadiness and dizziness.
  • Wear low-heeled shoes with good tread for better grip.
  • Change your surroundings by removing tripping hazards like clutter, loose rugs and poorly lit areas.
  • Avoid sudden position changes; stand up slowly and take your time to move around.
  • Watch out for rapid head movements that might trigger dizziness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Do not take Gravol Tablet if you are allergic to any of its contents. Before taking Gravol Tablet , please tell your doctor if you are using any antidepressants. Gravol Tablet is not intended for prolonged use unless prescribed by a physician. Inform your doctor if you are pregnant or breastfeeding. Antihistamines overdosage may cause hallucinations, convulsions, or death, especially in infants and children; it also produces excitation in younger children. So, dose adjustments may be necessary if prescribed to children. Gravol Tablet should not be given to children below 2 years of age and patients who are unconscious or have severe drowsiness, dizziness, or headache. Inform your doctor if you have difficulty breathing, asthma or bronchitis (lung problems), epilepsy (fits), serious heart problems, liver or kidney problems, a stomach blockage, hearing problems, or increased pressure in the eye (glaucoma). 

Drug-Drug Interactions

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DiphenhydramineEliglustat
Critical
DiphenhydraminePotassium citrate
Critical

Drug-Drug Interactions

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DiphenhydramineEliglustat
Critical
How does the drug interact with Gravol Tablet:
When Gravol Tablet is taken with Eliglustat, it can cause a decrease in metabolism.

How to manage the interaction:
Taking Gravol Tablet with Eliglustat is not recommended, please consult your doctor before taking it. It can be taken if prescribed by your doctor. Do not stop taking any medication without consulting your doctor.
DiphenhydraminePotassium citrate
Critical
How does the drug interact with Gravol Tablet:
Taking Gravol Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Gravol Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gravol Tablet:
When Thioridazine is taken with Gravol Tablet, it can slow down the way Gravol Tablet is broken down in the body.

How to manage the interaction:
Taking Gravol Tablet with Thioridazine is not recommended, please consult your doctor before taking it. It can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
DiphenhydramineSodium oxybate
Critical
How does the drug interact with Gravol Tablet:
Taking Gravol Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Gravol Tablet with Sodium oxybate is not recommended, but it can be taken if prescribed by a doctor. However contact your doctor if you experience shortness of breath, increased sweating, palpitations, or confusion. Do not stop using any medications without consulting a doctor.
How does the drug interact with Gravol Tablet:
Taking Gravol Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Gravol Tablet with Potassium chloride is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, contact your doctor. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Gravol Tablet:
Topiramate can induce elevated body temperature and decreased sweating, which can be exacerbated when combined with drugs that have similar effects, such as Gravol Tablet.

How to manage the interaction:
Although taking Gravol Tablet with Topiramate can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is essential to stay hydrated by drinking enough fluids, especially in hot weather and when doing physical activity. Contact your doctor immediately if you notice decreased sweating, fever, dizziness, drowsy, or lightheadedness. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Gravol Tablet:
Coadministration of Zonisamide with Gravol Tablet can induce elevated body temperature and decreased sweating.

How to manage the interaction:
Although taking Gravol Tablet with Zonisamide can result in an interaction, they can be taken together if prescribed by your doctor. It is essential to stay hydrated by drinking enough fluids, especially in hot weather and when doing physical activity. Contact a doctor immediately if you notice decreased sweating, fever, dizziness, drowsy, or lightheadedness. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Gravol Tablet:
Gravol Tablet reduces the blood levels and effectiveness of tamoxifen.

How to manage the interaction:
Although taking Gravol Tablet with Tamoxifen can possibly reduce the effectiveness of Tamoxifen, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DiphenhydramineBrexpiprazole
Severe
How does the drug interact with Gravol Tablet:
Gravol Tablet increases the blood levels of Brexpiprazole. This increases the risk of Side effects.

How to manage the interaction:
Taking Gravol Tablet with Brexpiprazole together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired, unusual muscle movements, muscle spasms, shaking or jerking in your arms and legs, feeling dizzy or lightheaded, or fainting - contact your doctor right away. Do not stop using any medications without talking to a doctor.
DiphenhydramineEsketamine
Severe
How does the drug interact with Gravol Tablet:
Taking Gravol Tablet with Esketamine can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Gravol Tablet with Esketamine can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, confusion, or difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • ​​​​​​Avoid spicy, greasy, and acidic foods before travelling; it may increase the feeling of sickness.
  • Opt for cereals, apples, bananas, or bread.
  • Breathe the fresh air, if possible, by opening the window.
  • In many cases, a full stomach and excessive heat may worsen the symptoms of motion sickness, space out your meals and eat light.
  • Position yourself where motion is least, like in the front seat of a car, centre of a boat or ship.
  • Avoid alcohol 24 hours before travel and during travel.

Habit Forming

No

Therapeutic Class

ANTIHISTAMINE

Gravol Tablet Substitute

Substitutes safety advice
  • Draminate 50 mg Tablet 10's

    by Others

    3.42per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, the use of Gravol Tablet can cause dry mouth. If you feel excessively thirsty, increase fluid intake, and avoid spicy and salty food.

Gravol Tablet is an anti-sickness medicine that takes about 30-60 minutes to show its action.

Gravol Tablet is usually recommended for short-term use. Do not take longer than prescribed unless advised by your doctor.

Drug-Drug Interactions Checker List

  • LORATADINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CODEINE
  • MORPHINE
  • HYDROCODONE
  • AMITRIPTYLINE
  • IMIPRAMINE
  • DIAZEPAM
  • ZOLPIDEM
  • GENTAMICIN

Disease/Condition Glossary

Motion sickness: It is an illness caused by motion during travel. It usually occurs when you are traveling by car, boat, plane, or train. Your body's sensory organs send mixed messages to your brain, causing dizziness, lightheadedness, or nausea and vomiting. The illness usually goes away when the motion stops. Symptoms include nausea, vomiting, dizziness, and tiredness.

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