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Prescription drugWhats That
Synonym
GLIMEPIRIDE+METFORMIN HYDROCHLORIDE
Composition
GLIMEPIRIDE-3MG + METFORMIN-850MG
Consume Type
ORAL
Return Policy
Not Returnable
Expires on or after
Apr-24
for this medicine
Drug-Drug Interactions
GlimepirideFurosemide
Severe
GlimepirideLeflunomide
Severe
Drug-Drug Interactions
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GlimepirideFurosemide
Severe
How does the drug interact with Gride-M 850 Tablet:
Co-administration of Furosemide may interfere with blood glucose control and lower the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with furosemide if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Furosemide may interfere with blood glucose control and lower the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with furosemide if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideLeflunomide
Severe
How does the drug interact with Gride-M 850 Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Leflunomide may increase the blood levels and effects of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideTrovafloxacin
Severe
How does the drug interact with Gride-M 850 Tablet:
When Gride-M 850 Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Gride-M 850 Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
When Gride-M 850 Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Gride-M 850 Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
GlimepirideParoxetine
Severe
How does the drug interact with Gride-M 850 Tablet:
Taking Gride-M 850 Tablet with Paroxetine may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Gride-M 850 Tablet with Paroxetine may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideAmprenavir
Severe
How does the drug interact with Gride-M 850 Tablet:
Co-administration of Amprenavir and Gride-M 850 Tablet may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although taking Gride-M 850 Tablet and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of Amprenavir and Gride-M 850 Tablet may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although taking Gride-M 850 Tablet and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideCiprofloxacin
Severe
How does the drug interact with Gride-M 850 Tablet:
Taking ciprofloxacin with Gride-M 850 Tablet can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).
How to manage the interaction:
Although taking ciprofloxacin and Gride-M 850 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
Taking ciprofloxacin with Gride-M 850 Tablet can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).
How to manage the interaction:
Although taking ciprofloxacin and Gride-M 850 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideGatifloxacin
Severe
How does the drug interact with Gride-M 850 Tablet:
Taking Gride-M 850 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Taking Gride-M 850 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.
How to manage the interaction:
Gatifloxacin is not recommended for patients with diabetes, however, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideBumetanide
Severe
How does the drug interact with Gride-M 850 Tablet:
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Gride-M 850 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
GlimepirideCitalopram
Severe
How does the drug interact with Gride-M 850 Tablet:
Taking Gride-M 850 Tablet with Citalopram may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Gride-M 850 Tablet with Citalopram may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideSibutramine
Severe
How does the drug interact with Gride-M 850 Tablet:
Taking Gride-M 850 Tablet with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Gride-M 850 Tablet with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Gride-M 850 Tablet can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Gride-M 850 Tablet 10's Substitute
Glycomet GP 3/850 Tablet 10's
by Others
₹9.99per tabletGepride M-3 Tablet 10's
by Others
₹12.78per tabletGluconorm-G Plus 3 Tablet 15's
by AYUR
₹15.84per tabletGlimisave M3 850 Tablet 15's
by AYUR
₹11.40per tabletGlitaray M-3 Plus Tablet 15's
by AYUR
₹11.88per tablet
Product Substitutes
Author Details
Drug-Diseases Interactions
GLIMEPIRIDE-3MG+METFORMIN-850MGHypertensive heart and renal disease
Severe
GLIMEPIRIDE-3MG+METFORMIN-850MGUnspecified kidney failure
Severe
Drug-Diseases Interactions
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GLIMEPIRIDE-3MG+METFORMIN-850MGHypertensive heart and renal disease
Severe
How does the disease interact with Gride-M 850 Tablet:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-3MG+METFORMIN-850MGUnspecified kidney failure
Severe
How does the disease interact with Gride-M 850 Tablet:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-3MG+METFORMIN-850MGOther disorders of adrenal gland
Moderate
How does the disease interact with Gride-M 850 Tablet:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-3MG+METFORMIN-850MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Gride-M 850 Tablet:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-3MG+METFORMIN-850MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Gride-M 850 Tablet:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
