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  3. Guficol 3miu Injection

Guficol 3miu Injection, Pack of 1 Injection
Guficol 3miu Injection, Pack of 1 Injection
Guficol 3miu Injection, Pack of 1 Injection
Guficol 3miu Injection, Pack of 1 Injection
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Synonym :

COLISTIN

Composition :

COLISTIMETHATE SODIUM-3MILLIONIU

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Guficol 3miu Injection

Guficol 3miu Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Guficol 3miu Injection contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Guficol 3miu Injection destroys the bacteria and successfully treats the infection.

Guficol 3miu Injection will be administered by a qualified healthcare professional. Sometimes, you may experience common side effects like injection site reactions, renal damage, visual disturbances, GI disturbances, dizziness, nausea, vomiting and muscle weakness. But these side effects are usually in the initial phase and resolve over time. However, if these side effects persist, let your doctor know.

Before receiving Guficol 3miu Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Guficol 3miu Injection can cause blurred vision and dizziness in some people; if this occurs, do not drive or operate tools or machinery. It is recommended not to consume any alcoholic beverages while on treatment with this medicine.

Uses of Guficol 3miu Injection

Bacterial infections

Directions for Use

Guficol 3miu Injection will be administered by a qualified healthcare professional. Do not self-administer.

Medicinal Benefits

Guficol 3miu Injection contains Colistimethate Sodium. Colistimethate Sodium, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Guficol 3miu Injection kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Guficol 3miu Injection, please inform your physician. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding before receiving Guficol 3miu Injection. Also, inform your doctor if you have chronic kidney disease, myasthenia gravis (muscle disorder), and porphyria (a blood disorder). Do not abruptly discontinue taking the prescription since this may result in antibiotic resistance, a condition in which bacteria develop resistance to antibiotics.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
ColistinTobramycin
Severe

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Guficol 3miu Injection:
Coadministration of Guficol 3miu Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Guficol 3miu Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinTobramycin
Severe
How does the drug interact with Guficol 3miu Injection:
Coadministration of Tobramycin with Guficol 3miu Injection can increase the blood levels and risk of Guficol 3miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Tobramycin, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
ColistinPancuronium
Severe
How does the drug interact with Guficol 3miu Injection:
Using Pancuronium with Guficol 3miu Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinGentamicin
Severe
How does the drug interact with Guficol 3miu Injection:
Co-administration of Guficol 3miu Injection with Gentamicin can increase the levels and risk of Guficol 3miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinKanamycin
Severe
How does the drug interact with Guficol 3miu Injection:
Coadministration of Guficol 3miu Injection with Kanamycin can increase the level and risk of Guficol 3miu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Kanamycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinStreptomycin
Severe
How does the drug interact with Guficol 3miu Injection:
Coadministration of Streptomycin with Guficol 3miu Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinTenofovir alafenamide
Severe
How does the drug interact with Guficol 3miu Injection:
Combining Guficol 3miu Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
ColistinVecuronium
Severe
How does the drug interact with Guficol 3miu Injection:
Using Vecuronium with Guficol 3miu Injection can make Vecuronium more effective in therapy.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Vecuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinPipecuronium bromide
Severe
How does the drug interact with Guficol 3miu Injection:
Coadministration of Pipecuronium bromide with Guficol 3miu Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and pipecuronium bromide, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Guficol 3miu Injection:
Combining Guficol 3miu Injection with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Guficol 3miu Injection and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After taking the full course of Guficol 3miu Injection, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking many calcium-enriched foods and drinks as it might affect the working of Guficol 3miu Injection.
  • Avoid intake of alcoholic beverages with Guficol 3miu Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Guficol 3miu Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Guficol 3miu Injection Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Guficol 3miu Injection contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Guficol 3miu Injection destroys the bacteria and successfully treats the infection.

Guficol 3miu Injection is contraindicated in people with Hypersensitivity to any component in Guficol 3miu Injection. Besides this, it is also contraindicated to use in people with myasthenia gravis (muscle disorder).

Guficol 3miu Injection contains Colistimethate Sodium. It is an antibiotic medication used when other drugs or therapy are ineffective. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Guficol 3miu Injection kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

Do not use anti diarrhoeal until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea as it may help increase the number of good bacteria in the intestine, which aids indigestion.

After taking an antibiotic, you may need to wait up to three hours to eat or drink dairy products, including milk and butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.

Drug-Drug Interactions Checker List

  • CYCLOBENZAPRINE
  • METAXALONE
  • AMPHOTERICIN B
  • CAPREOMYCIN
  • VANCOMYCIN

Special Advise

  • Regular blood tests are required to monitor kidney functions while taking Guficol 3miu Injection.
  • A Healthcare professional should always give a Guficol 3miu Injection to a hospital. Never self-administer.

Disease/Condition Glossary

Bacterial infections: A bacterial infection occurs when harmful bacteria enter the body, multiply, and infect it. It may attack any region of the body and multiply swiftly. Fever, chills, and tiredness are common symptoms. Bacteria come in a variety of shapes, including spherical, rod, and spiral-shaped bacteria. Bacterial infections range in severity from simple ailments such as sore throats and ear infections to serious brain infections such as meningitis and encephalitis. A bacterial infection can infect anyone at any time. People with a weakened immune system or who are on immunosuppressive medications, on the other hand, are more vulnerable to bacterial infection.

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