Hansepran 50 Capsule 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Veda Maddala , M Pharmacy

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About Hansepran 50 Capsule

Hansepran 50 Capsule belongs to the group of medicines called antileprotic drugs primarily used to treat Leprosy (infectious disease-causing skin lesions and nerve damage). Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae, which is a chronic infectious disease. The illness mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.

Clofazimine is the active component in Hansepran 50 Capsule . It works by inhibiting the growth of disease-causing organisms (Mycobacterium) in the body. Thus, Hansepran 50 Capsule aids in the treatment of Leprosy.

Take Hansepran 50 Capsule daily at the same time to ensure better efficacy. The dose and duration of Hansepran 50 Capsule can vary depending upon your condition and the severity of the infection. In some situations, you may experience symptoms such as stomach and epigastric pain, diarrhoea, nausea, and vomiting. These negative impacts do not necessitate medical treatment and will gradually subside. However, if you are experiencing these undesirable effects frequently, you should consult your doctor.

Continue using Hansepran 50 Capsule for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Hansepran 50 Capsule . Hansepran 50 Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Hansepran 50 Capsule . If pregnant or breastfeeding, consult your doctor before using Hansepran 50 Capsule . Do not use Hansepran 50 Capsule in more than specified doses or for an extended time. Before taking Hansepran 50 Capsule , inform your doctor about your medical history and any other medications you currently use to rule out possible side effects.

Uses of Hansepran 50 Capsule

Leprosy

Directions for Use

Chew the tablet completely and swallow. Do not swallow it as a whole.

Medicinal Benefits

Hansepran 50 Capsule contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe Hansepran 50 Capsule to treat various bacterial infections due to Mycobacterium.

Storage

Keep Hansepran 50 Capsule out of reach and sight of children.

Side effects of Hansepran 50 Capsule

Skin Discoloration

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Discomfort In Upper Abdomen

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Stomach Upset

Avoid triggering foods like spicy and fatty foods.
Eat smaller meals and digestible foods.
Regular exercise can improve gastrointestinal health.
Avoid sleeping immediately after eating as it can worsen digestion and lead to discomfort.
Drink plenty of water to stay hydrated.
Manage stress through relaxation techniques.

Drug Warnings

Continue using Hansepran 50 Capsule for as long as your doctor has prescribed it to treat your illness effectively. Please inform your doctor if you have ever had an allergic response to this drug before beginning treatment with Hansepran 50 Capsule . Hansepran 50 Capsule may cause dizziness, drowsiness, or reduced alertness. Therefore, drive or operate machinery only if you are alert after taking Hansepran 50 Capsule . If pregnant or breastfeeding, consult your doctor before using Hansepran 50 Capsule . Do not use Hansepran 50 Capsule in more than specified doses or for an extended time. Before taking Hansepran 50 Capsule , inform your doctor about your medical history and any other medications you currently use to rule out possible side effects. Sun lamps should be avoided. Clofazimine may increase your skin's sensitivity to sunlight or sunlamps. Therefore, wear protective clothing when exposed to direct sunlight and apply sunscreen with an SPF of at least 15.

Drug-Drug Interactions

ClofazimineZiprasidone

Critical

ClofazimineDronedarone

Critical

Drug-Drug Interactions

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ClofazimineZiprasidone

Critical

How does the drug interact with Hansepran 50 Capsule:
Taking Hansepran 50 Capsule with Ziprasidone can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Ziprasidone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineDronedarone

Critical

How does the drug interact with Hansepran 50 Capsule:
When Hansepran 50 Capsule is taken with Dronedarone, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Dronedarone is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineThioridazine

Critical

How does the drug interact with Hansepran 50 Capsule:
When Hansepran 50 Capsule is taken with Thioridazine, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Thioridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineCisapride

Critical

How does the drug interact with Hansepran 50 Capsule:
When Hansepran 50 Capsule is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Cisapride is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineMesoridazine

Critical

How does the drug interact with Hansepran 50 Capsule:
When Hansepran 50 Capsule is taken with Mesoridazine, it can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Mesoridazine is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineDofetilide

Critical

How does the drug interact with Hansepran 50 Capsule:
When Hansepran 50 Capsule is taken with Dofetilide, can increase the risk of an irregular heart rhythm that may be serious. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Using Hansepran 50 Capsule with Dofetilide is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.

ClofazimineEfavirenz

Severe

How does the drug interact with Hansepran 50 Capsule:
Co-administration of efavirenz with Hansepran 50 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking efavirenz with Hansepran 50 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

ClofazimineSparfloxacin

Severe

How does the drug interact with Hansepran 50 Capsule:
Co-administration of sparfloxacin with Hansepran 50 Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking sparfloxacin with Hansepran 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

ClofazimineIvabradine

Severe

How does the drug interact with Hansepran 50 Capsule:
Co-administration of ivabradine with Hansepran 50 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking Ivabradine with Hansepran 50 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

ClofazimineMethadone

Severe

How does the drug interact with Hansepran 50 Capsule:
Co-administration of methadone with Hansepran 50 Capsule can increase the risk of irregular heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Taking methadone with Hansepran 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach and blueberries.
Consuming food rich in probiotics helps develop the immune system against allergies.
Limit intake of food that might trigger allergies, such as dairy products, soy, eggs and nuts.
Avoid consuming foods with excess sugar, as it may flare up inflammation.
Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
Reducing stress and maintaining a good sleep cycle would be helpful.
Avoid getting in contact with harsh soaps, detergents and rough fabrics.

Side Effects of Hansepran 50 Capsule

Stomach pain
Diarrhoea
Nausea
Vomiting
Dizziness
Drowsiness

Habit Forming

No

Therapeutic Class

ANTILEPROTICS

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Hansepran 50 Capsule work?

Hansepran 50 Capsule contains Clofazimine, an antileprotic drug used in treating Leprosy in conjunction with other medications. It works by preventing the growth of disease-causing pathogens in the body. Thus, it aids in the treatment of Leprosy. The doctor may prescribe Hansepran 50 Capsule treat various bacterial infections due to Mycobacterium.

Drug-Drug Interactions Checker List

AZITHROMYCIN
TRIMETHOPRIM
SULFAMETHOXAZOLE
ALUMINIUM HYDROXIDE
MAGNESIUM HYDROXIDE
SIMETHICONE

Disease/Condition Glossary

Leprosy: Leprosy, commonly known as Hansen's disease, is caused by Mycobacterium leprae. It is a chronic infectious disease that mostly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory system, and the eyes. Leprosy can affect anyone at any age, from infancy to old age.