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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

About HAPPI 20MG I.V INJECTION

HAPPI 20MG I.V INJECTION belongs to a group of antiulcer medicines called proton pump inhibitors used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.

HAPPI 20MG I.V INJECTION contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

In some cases, you may experience certain common side-effects such as pain at the site of injection, diarrhoea, dizziness, dry mouth, headache, and abdominal pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

On long-term treatment, HAPPI 20MG I.V INJECTION may cause low magnesium levels, vitamin B12 levels and increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. HAPPI 20MG I.V INJECTION may cause dizziness, so drive only if you are alert. HAPPI 20MG I.V INJECTION is not recommended for children as safety has not been established. Avoid consuming alcohol along with HAPPI 20MG I.V INJECTION as it could lead to increased drowsiness and can elevate the production of stomach acid.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

RABEPRAZOLE-20MG

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of HAPPI 20MG I.V INJECTION

Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, Zollinger-Ellison syndrome.

Medicinal Benefits

HAPPI 20MG I.V INJECTION belongs to a group of antiulcer medicines called proton pump inhibitors. HAPPI 20MG I.V INJECTION is used to treat gastric ulcers, duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome. HAPPI 20MG I.V INJECTION works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Side Effects of HAPPI 20MG I.V INJECTION

  • Pain at the site of injection
  • Diarrhoea
  • Dry mouth
  • Dizziness
  • Headache
  • Abdominal pain

Directions for Use

HAPPI 20MG I.V INJECTION will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take HAPPI 20MG I.V INJECTION if you are allergic to any of its contents. Inform your doctor if you have a stomach tumour, liver disease, or if you are due to have Chromogranin A blood test. On long-term treatment, HAPPI 20MG I.V INJECTION may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor before starting HAPPI 20MG I.V INJECTION if you are pregnant or breastfeeding. HAPPI 20MG I.V INJECTION may cause dizziness, so drive only if you are alert. HAPPI 20MG I.V INJECTION is not recommended for children as safety has not been established. Avoid consuming alcohol along with HAPPI 20MG I.V INJECTION as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Therapeutic Class

ANTIULCERANTS

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with HAPPI 20MG I.V INJECTION:
When used in combination with erlotinib, HAPPI 20MG I.V INJECTION may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking HAPPI 20MG I.V INJECTION with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with HAPPI 20MG I.V INJECTION:
Co-administration of HAPPI 20MG I.V INJECTION can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking HAPPI 20MG I.V INJECTION with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleDasatinib
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking HAPPI 20MG I.V INJECTION together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking HAPPI 20MG I.V INJECTION and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking HAPPI 20MG I.V INJECTION together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking HAPPI 20MG I.V INJECTION and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleClopidogrel
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking Clopidogrel with HAPPI 20MG I.V INJECTION can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and HAPPI 20MG I.V INJECTION together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
RabeprazoleGefitinib
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking HAPPI 20MG I.V INJECTION together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking HAPPI 20MG I.V INJECTION and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after HAPPI 20MG I.V INJECTION. Do not discontinue any medications without a doctor's advice.
RabeprazoleDasatinib
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking Dasatinib with HAPPI 20MG I.V INJECTION may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking HAPPI 20MG I.V INJECTION with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
RabeprazolePhenytoin
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
When Phenytoin and HAPPI 20MG I.V INJECTION are taken in combination, Phenytoin will reduce the concentration or impact of HAPPI 20MG I.V INJECTION.

How to manage the interaction:
Although taking Phenytoin and HAPPI 20MG I.V INJECTION together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleMethotrexate
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Co-administration of Methotrexate with HAPPI 20MG I.V INJECTION can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between HAPPI 20MG I.V INJECTION and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with HAPPI 20MG I.V INJECTION:
Taking HAPPI 20MG I.V INJECTION together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking HAPPI 20MG I.V INJECTION and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Special Advise

  • Inform your doctor before taking HAPPI 20MG I.V INJECTION if you are due to have Chromogranin A blood test.
  • HAPPI 20MG I.V INJECTION may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking HAPPI 20MG I.V INJECTION.
  • HAPPI 20MG I.V INJECTION may increase the risk of infections. Consult your doctor if you notice any signs or symptoms of infections.

Author Details

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Disease/Condition Glossary

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, peptic ulcer, and Zollinger Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Gastric/duodenal ulcer: It is a painful condition followed by the development of sores or ulcers in the duodenum or stomach lining.

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

HAPPI 20MG I.V INJECTION Substitute

Substitutes safety advice
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