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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Composition :

HEPARIN-25000IU

Manufacturer/Marketer :

Gland Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Hep 25 Injection

Hep 25 Injection belongs to a class of drugs called anticoagulants or blood thinners. Hep 25 Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hep 25 Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Hep 25 Injection will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hep 25 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hep 25 Injection or any other medicines, please tell your doctor. It is not known whether Hep 25 Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hep 25 Injection. Hep 25 Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hep 25 Injection.

Uses of Hep 25 Injection

Prevention of blood clots.

Directions for Use

Hep 25 Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Hep 25 Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hep 25 Injection also reduces the risk of blood clots during surgeries (like heart surgery). Hep 25 Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Hep 25 Injection
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Use Hep 25 Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hep 25 Injection. Patients should inform the doctor that they are receiving Hep 25 Injection before any surgery is scheduled.

Drug-Drug Interactions

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HeparinBazedoxifene
Critical

Drug-Drug Interactions

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How does the drug interact with Hep 25 Injection:
Taking Alteplase with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hep 25 Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hep 25 Injection:
When Hep 25 Injection is taken with bazedoxifene the effects of Hep 25 Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hep 25 Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Tenecteplase with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Hep 25 Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Mifepristone with Hep 25 Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Hep 25 Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Hep 25 Injection:
Using Hep 25 Injection with Oritavancin can make Hep 25 Injection less effective as a therapy.

How to manage the interaction:
Hep 25 Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hep 25 Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Ticlopidine with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hep 25 Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Coadministration of Ketorolac with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Hep 25 Injection, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hep 25 Injection:
Taking Tirofiban with Hep 25 Injection can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Hep 25 Injection and Tirofiban, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HeparinOmacetaxine mepesuccinate
Severe
How does the drug interact with Hep 25 Injection:
Taking Hep 25 Injection with Omacetaxine mepesuccinate can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Omacetaxine mepesuccinate with Hep 25 Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hep 25 Injection:
Coadministration of Hep 25 Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Hep 25 Injection and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Hep 25 Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hep 25 Injection.

Yes, Hep 25 Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Hep 25 Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Hep 25 Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hep 25 Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Hep 25 Injection to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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