Hetriva 18 Transdermal Patch 1's

Written By Divya L , PharmaD

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹80

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Whats That

About Hetriva 18 Transdermal Patch

Hetriva 18 Transdermal Patch belongs to a group of medicines called 'anti-dementia agents' used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease. Alzheimer's disease is a neurological disorder, which causes dementia (memory loss), and slowly destroys the ability to think, learn, communicate, and handle daily activities. Parkinson's disease is a central nervous system disorder that affects movement leading to shaking, stiffness, and difficulty with walking, balance, and coordination.

Hetriva 18 Transdermal Patch contains 'Rivastigmine' that belongs to the class of 'Acetylcholinesterase Inhibitors'. Rivastigmine increases the cholinergic effects allowing the nerve cells to communicate. It restores the balance of neurotransmitters and improves mental function, such as memory and thinking. Neurotransmitters are chemical messengers that transmit the message from one nerve cell to another nerve cell, muscle cell, or gland cell.

Use Hetriva 18 Transdermal Patch as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your disease. Common side effects of Hetriva 18 Transdermal Patch include nausea, vomiting, diarrhoea, stomach upset, stomach pain, headache, anxiety, depression/low mood, trouble sleeping, dizziness, drowsiness, shakiness (tremor), weakness/tiredness, weight loss/loss of appetite, and skin irritation at the application site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you are taking any prescription and non-prescription medications, including other vitamins, before using Hetriva 18 Transdermal Patch. Please tell your doctor if you are allergic to any medicines. Inform your doctor beforehand if you have a history of liver or kidney diseases, breathing problems (asthma, chronic obstructive pulmonary disease (COPD)), stomach/intestinal problems (ulcers, bleeding), heart diseases (sick sinus syndrome and conduction disorders), fainting, fits, urination problems, and enlarged prostate. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoid consuming alcohol and driving/operating machinery while being treated with Hetriva 18 Transdermal Patch as it can make you dizzy or drowsy.

Uses of Hetriva 18 Transdermal Patch

Dementia in Alzheimer's and Parkinson's diseases.

Directions for Use

Apply the transdermal patch evenly on the skin without hair. It is advised to put the transdermal patch on clean, dry, and healthy skin on the upper or lower back. You can also apply it to the upper arm or chest. The patch should not be put on damaged and broken skin. Please do not apply a new patch when you are already using one patch since it can lead to overdosing.

Medicinal Benefits

Hetriva 18 Transdermal Patch treats mild to moderate dementia caused by Alzheimer's and Parkinson's diseases. It contains 'Rivastigmine', an acetylcholinesterase inhibitor. Rivastigmine increases acetylcholine (a brain chemical) levels in the central nervous system involved in transmitting nerve signals that play an essential role in memory. Hetriva 18 Transdermal Patch is not a cure for Alzheimer's and Parkinson's diseases but improves memory, thinking awareness, and the ability to perform daily functions.

Storage

Keep out of sight and reach of children.

Side effects of Hetriva 18 Transdermal Patch

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Weight Loss

Weight loss without physical activity needs immediate medical attention.
Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
Talk to your dietician and consume food which can maintain ideal weight.

Drug Warnings

Let your doctor know if you use any other medicines or supplements before using Hetriva 18 Transdermal Patch. Brief your medical history if you have any liver or kidney diseases, breathing problems (asthma, chronic obstructive pulmonary disease (COPD)), stomach/intestinal problems (ulcers, bleeding), heart diseases (sick sinus syndrome and other conduction disorders), fainting, fits, urination problems, and enlarged prostate. Do not apply another patch when you are already using a patch since it can lead to overdosing. Please consult your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoid consuming alcohol while being treated with Hetriva 18 Transdermal Patch as it might lead to increased side effects. Do not drive or operate machinery as this medicine may cause dizziness and sleepiness. Hetriva 18 Transdermal Patch is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

RivastigmineMetrizamide

Severe

RivastigmineBupropion

Severe

Drug-Drug Interactions

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RivastigmineMetrizamide

Severe

How does the drug interact with Hetriva 18 Transdermal Patch:
Taking Hetriva 18 Transdermal Patch and Metrizamide together may increase the risk of developing seizures (fits).

How to manage the interaction:
Although taking Hetriva 18 Transdermal Patch and Metrizamide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms like muscle spasms, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

RivastigmineBupropion

Severe

How does the drug interact with Hetriva 18 Transdermal Patch:
Talking bupropion and Hetriva 18 Transdermal Patch together can increase risk of having seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Hetriva 18 Transdermal Patch can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like muscle spasms or movements, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not discontinue any medications without consulting a doctor.

RivastigminePropranolol

Severe

How does the drug interact with Hetriva 18 Transdermal Patch:
Coadministration of Hetriva 18 Transdermal Patch with propranolol can cause an abnormally slow heart rate and low blood pressure.

How to manage the interaction:
Although taking Propranolol together with Hetriva 18 Transdermal Patch can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.

RivastigmineTramadol

Severe

How does the drug interact with Hetriva 18 Transdermal Patch:
Taking Tramadol with Hetriva 18 Transdermal Patch can significantly increase the risk of seizures (fits).

How to manage the interaction:
Taking Hetriva 18 Transdermal Patch with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RivastigmineBisoprolol

Moderate

How does the drug interact with Hetriva 18 Transdermal Patch:
Hetriva 18 Transdermal Patch may occasionally cause excessively slow heart rate and low blood pressure, and using it with bisoprolol may increase that risk.

How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Hetriva 18 Transdermal Patch if prescribed by the doctor. Consult the prescriber if you develop headache, dizziness, lightheadedness, fainting, or irregular heart rate.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain proper weight by following a healthy diet.
Exercise regularly as it helps in less cognitive decline and brain volume loss.
Avoid smoking and alcohol consumption.
Try to avoid stress by practising meditation or yoga.
Include fruits and vegetables in your diet as they contain antioxidants.
Eat nutritious food as it helps in cognitive stimulation.
Limit foods with high cholesterol and saturated fats.
Cut down on sugar, salt and processed foods.
Drink plenty of water.
Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Side Effects of Hetriva 18 Transdermal Patch

Nausea
Vomiting
Diarrhoea
Stomach upset
Stomach pain
Headache
Anxiety
Depression/low mood
Trouble sleeping
Dizziness
Drowsiness
Shakiness (tremor)
Weakness/tiredness
Weight loss/loss of appetite
Skin irritation at the application site

Habit Forming

No

Therapeutic Class

ANTI- ALZHEIMER'S AGENTS

Author Details

Written By

Divya L

PharmaD

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Hetriva 18 Transdermal Patch work?

Hetriva 18 Transdermal Patch contains 'Rivastigmine', an acetylcholinesterase inhibitor. It treats dementia in Alzheimer's and Parkinson's diseases by increasing acetylcholine levels in the central nervous system and enhancing the neurotransmission process. Thus, Hetriva 18 Transdermal Patch improves memory, thinking, and awareness.

In which conditions should I stay cautious while using Hetriva 18 Transdermal Patch?

Hetriva 18 Transdermal Patch should be used with caution in the medical history of liver or kidney diseases, breathing problems (asthma, chronic obstructive pulmonary disease (COPD)), stomach/intestinal problems (ulcers, bleeding), heart diseases (sick sinus syndrome and other conduction disorders), fainting, fits, urination problems, and enlarged prostate. Please let your doctor know if you have any other medical problems before starting Hetriva 18 Transdermal Patch.

What should I be aware of while using a transdermal patch?

The transdermal patch is to be evenly applied on the skin without hair. It is advised to put the transdermal patch on clean, dry, and healthy skin on the upper or lower back. You can also apply it to the upper arm or chest. The patch should not be put on damaged and broken skin. Please do not apply a new patch when you are already using one patch since it can lead to overdosing. Do not apply creams, oils, lotions, and powder on the site of the application. Sometimes, a patch may contain metal. Hence, it is advised to take off the patch while undergoing an MRI scan.

How to discard the used patch?

After using the patch, fold it into half with the adhesive surfaces pressed together inwards, and discard it safely.

How to store Hetriva 18 Transdermal Patch?

Store Hetriva 18 Transdermal Patch in a dry place at room temperature ranging from 20°C to 25°C. Do not store in the washroom. Do not open the sealed pouch/sachet until the patch is ready to use.

Drug-Drug Interactions Checker List

ASPIRIN
NAPROXEN
METOCLOPRAMIDE
OXYBUTYNIN
TOLTERODINE
ATENOLOL

Special Advise

Let your doctor know that you are using Hetriva 18 Transdermal Patch if you are undergoing any medical tests.
Sometimes, a patch may contain metal. Hence, it is advised to take off the patch while undergoing an MRI scan.

Disease/Condition Glossary

Alzheimer's disease: The disease is named after Dr Alois Alzheimer, who was the first to discover the disease. Alzheimer's disease is a neurological disorder that causes dementia (memory loss), and slowly destroys the ability to think, learn, communicate, and eventually, the ability to handle daily activities. It is the most common cause of dementia (memory loss) in adults. Dementia is the loss of cognitive functioning, such as remembering, thinking, and reasoning. The causes of this disease are abnormal functioning of brain cells which causes a disturbance in communication between them. The risk factors are age, family history and genetics of a person. Alzheimer's disease symptoms include memory loss, trouble with familiar tasks, difficulties with problem-solving, trouble with writing or talking, disorientation, problems with reasoning or judgment, and mood and personality changes. In most people, the symptoms of Alzheimer's appear in their mid-60s.

Parkinson's disease: It is a central nervous system disorder that affects movement leading to shaking, stiffness, and difficulty with walking, balance, and coordination. This disease affects the nerve cells in the brain that produce dopamine (neurotransmitter). Parkinson's disease symptoms include dementia, muscle rigidity, tremors, and changes in speech and gait (pattern of limb movement). This disease generally occurs in people aged 60 years and over. Risk factors of this disease include genetics, environmental triggers, and certain toxins.