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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer

Lincoln Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Histolin DX Syrup

Histolin DX Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat cough due to runny nose, sneezing, and throat irritation. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) produces mucous or sputum. 

Histolin DX Syrup is a combination of two drugs, namely: Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.  Dextromethorphan hydrobromide blocks the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, Histolin DX Syrup helps to relieve cough, cold and allergic symptoms. 

Your doctor will recommend the dose and duration of Histolin DX Syrup based on your medical condition. Some people may experience dry mouth/throat/nose, drowsiness, blurred vision, constipation, dizziness, and restlessness. Most of these side effects of Histolin DX Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before starting Histolin DX Syrup. Histolin DX Syrup is not recommended for children below 2 years of age. Histolin DX Syrup may cause dizziness, so drive only if you are alert. Avoid alcohol consumption along with Histolin DX Syrup as it may cause increased dizziness and drowsiness. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Histolin DX Syrup

Cough 

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Histolin DX Syrup is a combination of two drugs: Chlorphenamine maleate (antihistamine) and Dextromethorphan hydrobromide (cough suppressant). Chlorphenamine maleate belongs to the class of antihistamines or anti-allergic that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Dextromethorphan hydrobromide belongs to the class of cough suppressants that block the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, together Histolin DX Syrup helps to relieve cough, cold and allergic symptoms. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Histolin DX Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Blurred vision
  • Constipation
  • Dizziness
  • Restlessness

Drug Warnings

Do not take Histolin DX Syrup if you are allergic to any of the contents. Avoid using Histolin DX Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. It is advised to seek medical help if the cough does not go away or if it is followed by a high fever, skin rash, or persistent headache. Histolin DX Syrup may cause drowsiness, dizziness, and blurred vision in some patients; therefore, drive only if you are alert. Histolin DX Syrup should not be used in elderly patients with confusion. Avoid alcohol consumption along with Histolin DX Syrup as it might cause increased dizziness.

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
DextromethorphanProcarbazine
Critical

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Pargyline and Histolin DX Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Histolin DX Syrup 60 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Histolin DX Syrup 60 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Histolin DX Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Phenelzine and Histolin DX Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Histolin DX Syrup 60 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Taking Rasagiline with Histolin DX Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Histolin DX Syrup 60 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Taking Tranylcypromine with Histolin DX Syrup 60 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Histolin DX Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Isocarboxazid with Histolin DX Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Histolin DX Syrup 60 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanSelegiline
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Histolin DX Syrup 60 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Histolin DX Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Taking Histolin DX Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Histolin DX Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Histolin DX Syrup 60 ml:
Taking Histolin DX Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Histolin DX Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
DextromethorphanFluvoxamine
Severe
How does the drug interact with Histolin DX Syrup 60 ml:
Co-administration of Histolin DX Syrup 60 ml and Fluvoxamine may increase the risk serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Histolin DX Syrup 60 ml and Fluvoxamine, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasm or stiffness, nausea, vomiting, stomach cramps, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods. Instead, replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts, and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid a dry throat. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough.
  • Eat fruits rich in water content, such as pears, watermelon, peaches, and pineapples.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Histolin DX Syrup Substitute

Substitutes safety advice
  • Corex DX Syrup 100 ml

    by Others

    1.40per tablet
  • Piriton CS Syrup 100 ml

    by Others

    1.23per tablet
  • Alkof DX Syrup 100 ml

    by Others

    1.08per tablet
  • Macbery DX Sugar Free Syrup 100 ml

    by AYUR

    1.04per tablet
  • Eskuf DX Syrup 100 ml

    by Others

    1.49per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Histolin DX Syrup contains Chlorphenamine maleate and Dextromethorphan hydrobromide. Chlorphenamine maleate blocks the action of histamine, a substance responsible for causing allergic reactions. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, decreasing the urge to cough.

Histolin DX Syrup may be used to relieve allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes. Histolin DX Syrup contains Chlorphenamine maleate, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.

Histolin DX Syrup may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Histolin DX Syrup to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

You are recommended to take Histolin DX Syrup for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after one week of using Histolin DX Syrup, please consult your doctor.

It is advised not to stop taking Histolin DX Syrup without consulting your doctor as it may worsen the cough or cause recurring symptoms. Therefore, take Histolin DX Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Histolin DX Syrup, please consult your doctor.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE

Special Advise

  • Talk to your doctor if the symptoms do not improve even after taking Histolin DX Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash, or headache after taking Histolin DX Syrup. 
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Histolin DX Syrup.

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Cough may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. A dry cough does not produce any mucus or phlegm. It usually occurs due to irritation in the airways. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. 

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