Histonate Plus Expectorant 110 ml belongs to the class of medications called expectorants primarily used to treat cough. Coughing (dry or productive) is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Histonate Plus Expectorant 110 ml is a combination of two drugs, namely: Salbutamol (bronchodilator) and Guaifenesin (expectorant). Salbutamol belongs to the class of bronchodilators that relaxes muscles and widens the airways. Thereby, it makes breathing easier. Guaifenesin belongs to the class of expectorants that works by increasing the volume of fluid in the airways, reduce the stickiness of mucus, and helps to remove it from the airways.

Take Histonate Plus Expectorant 110 ml as prescribed. Your doctor will recommend how often you take Histonate Plus Expectorant 110 ml based on your medical condition. Some people may experience nausea, vomiting, drowsiness, stomach upset, headache, dizziness, skin rash, tremor, restlessness, tension and rapid heartbeat. Most of these side effects of Histonate Plus Expectorant 110 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Histonate Plus Expectorant 110 ml or any other medicines, please tell your doctor. Histonate Plus Expectorant 110 ml is not recommended for children below 2 years of age, as the safety and effectiveness were not established. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Histonate Plus Expectorant 110 ml. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Histonate Plus Expectorant 110 ml. If you are about to undergo any surgery that requires anesthesia, please inform your doctor that you are taking Histonate Plus Expectorant 110 ml. If you experience constipation, leg cramps, numbness or tingling, increased urination or thirst, muscle weakness, or irregular heartbeats, contact your doctor as it may be due to low potassium levels in the blood. Drink plenty of fluids while taking Histonate Plus Expectorant 110 ml to loosen mucus. If you have diabetes, asthma, overactive thyroid, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), kidney, liver, or heart problems, inform your doctor before taking Histonate Plus Expectorant 110 ml.

Histonate Plus Expectorant 110 ml is a combination of two drugs, namely: Salbutamol (bronchodilator) and Guaifenesin (expectorant). Together Histonate Plus Expectorant 110 ml helps to relieve respiratory obstruction and improve pulmonary ventilation, especially in the conditions of respiratory disorders like asthma, bronchitis, and emphysema. Histonate Plus Expectorant 110 ml minimizes the bronchospasm (sudden narrowing of airways) and excessive secretion of viscous mucus (which blocks airways). 

• Nausea
• Vomiting
• Drowsiness
• Stomach upset
• Headache
• Dizziness
• Skin rash
• Tremor
• Restlessness
• Tension
• Rapid heartbeat

If you are allergic to Histonate Plus Expectorant 110 ml or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Histonate Plus Expectorant 110 ml. Histonate Plus Expectorant 110 ml is not recommended for children below 2 years of age, as the safety and effectiveness were not established. If you have diabetes, regular monitoring of blood sugar levels is recommended while taking Histonate Plus Expectorant 110 ml. If you are about to undergo any surgery that requires anesthesia, please inform your doctor that you are taking Histonate Plus Expectorant 110 ml. If you experience constipation, leg cramps, numbness or tingling, increased urination or thirst, muscle weakness, or irregular heartbeats, contact your doctor as it may be due to low potassium levels in the blood. Drink plenty of fluids while taking Histonate Plus Expectorant 110 ml to loosen mucus. If you have diabetes, asthma, overactive thyroid, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), kidney, liver, or heart problems, inform your doctor before taking Histonate Plus Expectorant 110 ml.

Drug-Drug Interaction: Histonate Plus Expectorant 110 ml may have interaction with medicines used to lower high blood pressure (propranolol, reserpine, methyldopa, guanethidine), tricyclic antidepressants (amitriptyline, imipramine, amoxapine).

Drug-Food Interaction: Histonate Plus Expectorant 110 ml may interact with caffeine. Therefore, avoid or limit the intake of caffeinated beverages, foods, or dietary supplements with Histonate Plus Expectorant 110 ml as it may increase the risk of adverse effects.

Drug-Disease Interaction: If you have diabetes, asthma, overactive thyroid, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), kidney, liver, or heart problems, inform your doctor before taking Histonate Plus Expectorant 110 ml.

• PROPRANOLOL
• RESERPINE
• METHYLDOPA
• GUANETHIDINE
• AMITRIPTYLINE
• IMIPRAMINE
• AMOXAPINE

• Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts, and chips with green leafy vegetables.
• Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
• Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches, and pineapples.

• Regularly monitor blood sugar levels while taking Histonate Plus Expectorant 110 ml, especially if you have diabetes as Histonate Plus Expectorant 110 ml may increase blood sugar levels.
• Monitor blood potassium levels while taking Histonate Plus Expectorant 110 ml, especially in asthma patients, as it may cause low potassium levels in the blood.

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-colored, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection. Cough production is common in asthma, COPD, and other respiratory disorders like bronchitis (airway inflammation and infection).