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Composition :

PROCARBAZINE-50MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hodpro 50mg Capsule

Hodpro 50mg Capsule belongs to the group of anti-cancer drugs and chemotherapeutic agents. Hodpro 50mg Capsule is used to treat cancers and malignant conditions such as Hodgkin’s disease (cancer that originates in the white blood cells) and certain brain tumours.

Hodpro 50mg Capsule contains ‘’Procarbazine.’’ Cancer is an uncontrolled growth of cells in the body. Hodpro 50mg Capsule interferes with the growth of cells, nipping it in the bud. It functions by inhibiting the molecular production of materials such as proteins and DNA necessary for cell growth and division.

Hodpro 50mg Capsule is a prescription-only medicine. It may be taken as a tablet at the same time every day. Hodpro 50mg Capsule may be taken with or without food. It should be swallowed as a whole and not chewed or broken down. Avoid consuming Hodpro 50mg Capsule with certain foods like cheese, smoked fish, fermented wine and meat.

In some cases, Hodpro 50mg Capsule may cause common side effects such as nausea, vomiting, bruising, cramps, rash and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

It is advisable to inform your doctor if you are allergic to Hodpro 50mg Capsule or any of its components. Keep your doctor informed if you suffer from kidney or liver disease, bleeding problems, anaemia or recurrent infections. Keep your doctor informed if you are on any radiation therapy. Consult your doctor if you are pregnant, planning pregnancy or breastfeeding before taking Hodpro 50mg Capsule as Hodpro 50mg Capsule is not recommended for routine use in these states. Consult your doctor before taking alcohol with Hodpro 50mg Capsule as there may be an interaction. Avoid smoking while taking Hodpro 50mg Capsule .

Uses of Hodpro 50mg Capsule

Hodgkin’s Lymphoma

Directions for Use

Take Hodpro 50mg Capsule as directed by the physician. Hodpro 50mg Capsule should be swallowed as a whole. Do not crush, chew or break it. Hodpro 50mg Capsule can be taken with or without food, but it is better to take it with food. Avoid tyramine-rich foods such as processed cheese, smoked fish and meats, overripe fruit, fermented wine and non-alcoholic beer with Hodpro 50mg Capsule intake. In case you have missed a dose, take it as soon as you remember unless it is too close to the time of the second dose. Do not take a double dose in any case. Do not stop taking Hodpro 50mg Capsule abruptly and/or without the supervision of your physician.

Medicinal Benefits

Hodpro 50mg Capsule is an antineoplastic/anti-cancer drug. It contains PROCARBAZINE. It is used primarily in the treatment of cancers, especially Hodgkin’s lymphoma. Hodpro 50mg Capsule shows antineoplastic activity, meaning it targets neoplastic (abnormally growing cells) in the body and inhibits their uncontrolled division and growth. Hodpro 50mg Capsule works by preventing DNA, RNA and protein synthesis required for the molecular development of cells. Hodpro 50mg Capsule also acts by destroying DNA, thereby arresting cell growth in the roots. Hence, Hodpro 50mg Capsule is very effective in cancer therapy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Hodpro 50mg Capsule
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Drink plenty of water (at least 8-10 glasses a day) to thin out bronchial secretions.
  • Consume warm liquids like tea, broth, or soup to help loosen thickened secretions.
  • Include omega-3 fatty acid-rich foods like fatty fish, flaxseeds, and walnuts to reduce inflammation.
  • Eat antioxidant-rich foods like fruits, vegetables, and nuts to combat oxidative stress.
  • Stay away from pollutants, dust, and second hand smoke, which can exacerbate thickened secretions.
  • Sleep with your head elevated using extra pillows to reduce congestion.
  • Engage in gentle exercises like yoga or walking to improve lung function.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Drug Warnings

Hodpro 50mg Capsule should not be used in case of any known allergy to either of the components. Avoid foods such as processed cheese, smoked fish, meats, overripe fruit, fermented wine, and yeast while taking Hodpro 50mg Capsule . Hodpro 50mg Capsule should be used with caution in case of high-risk or previous history cancers, cardiovascular health disorders, bleeding disorders, kidney disease, liver disease or anaemia. Keep your doctor informed of your medical history and if you suffer from epilepsy, an adrenal tumour such as phaeochromocytoma, or have had a stroke. Consult your doctor before using Hodpro 50mg Capsule during pregnancy, breastfeeding, or even if you are trying to get pregnant. Keep your doctor informed if you are on painkillers or using any nasal decongestants or anti-anxiety, anti-depressant, antiepileptic, anaesthetic or analgesic medications. Keep your doctor informed in case you are undergoing any radiation therapy. Inform your doctor of your vaccination history and do not take any vaccines without consent. Avoid contact with those who have recently received live vaccines (like the nasal flu, pox, or MMR vaccine). Hodpro 50mg Capsule makes your skin more sensitive to UV radiation. Wear sunscreen and protective clothing while venturing out in the sun. Hodpro 50mg Capsule may interact with alcohol, please consult your doctor before use. Hodpro 50mg Capsule may cause dizziness and is not recommended to take while driving or operating heavy machinery.

Drug-Drug Interactions

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ProcarbazineLevodopa
Critical

Drug-Drug Interactions

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ProcarbazineLevodopa
Critical
How does the drug interact with Hodpro 50mg Capsule:
Using levodopa together with Hodpro 50mg Capsule can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Hodpro 50mg Capsule with Levodopa together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Hodpro 50mg Capsule:
Taking Carbamazepine with Hodpro 50mg Capsule may cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine with Hodpro 50mg Capsule is generally not advised, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hodpro 50mg Capsule:
Combining Hodpro 50mg Capsule and Desvenlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Hodpro 50mg Capsule and Desvenlafaxine together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. you should wait at least 14 days after stopping isocarboxazid before you start treatment with desvenlafaxine and do not discontinue any medications without first consulting your doctor.
How does the drug interact with Hodpro 50mg Capsule:
Using Hodpro 50mg Capsule together with atomoxetine can cause dangerously high blood pressure.

How to manage the interaction:
Taking Hodpro 50mg Capsule with Atomoxetine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not stop using any medications without talking to a doctor.
ProcarbazineEphedrine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Taking Ephedrine and Hodpro 50mg Capsule together can increase the risk of high blood pressure.

How to manage the interaction:
Taking Ephedrine and Hodpro 50mg Capsule together is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, disorientation, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, you should consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hodpro 50mg Capsule:
Taking Hodpro 50mg Capsule with mephentermine together may increase the hypertensive activities of Mephentermine.

How to manage the interaction:
Taking Mephentermine with Hodpro 50mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hodpro 50mg Capsule:
When Rizatriptan is taken with Hodpro 50mg Capsule can increase the risk of high blood pressure.

How to manage the interaction:
Taking Rizatriptan with Hodpro 50mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately If you experience symptoms such as severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hodpro 50mg Capsule:
Taking duloxetine with Hodpro 50mg Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duloxetine with Hodpro 50mg Capsule is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Hodpro 50mg Capsule:
When Vortioxetine is taken with Hodpro 50mg Capsule, it can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Vortioxetine with Hodpro 50mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hodpro 50mg Capsule:
Using Amitriptyline together with Hodpro 50mg Capsule can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Hodpro 50mg Capsule and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your doctor informed if you are planning to or are pregnant.

  • Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.

  • Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.

  • Cut back on foods that are high in tyramine such as overripe fruit, processed cheese, smoked fish, meat etc. Eat more healthy meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.

  • Avoid taking Hodpro 50mg Capsule with alcohol as there may be an interaction.

  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.

  • Taking a stroll in the garden, or spending 30 mins of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.

  • Avoid tobacco use as smoking can increase the chances of lung cancer when used with Hodpro 50mg Capsule . Inform your doctor in case of marijuana use.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Hodpro 50mg Capsule works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Please consult your physician before altering your chemotherapy as any misguided change can cause serious side effects. One of the side effects of Hodpro 50mg Capsule is also hair loss. Hence it is best to discuss your treatment plan with your doctor.

If you suffer from IBD, you may be on anticholinergic therapy which may interfere with Hodpro 50mg Capsule . Please consult your doctor before use and discuss any concerns with your doctor.

Hodpro 50mg Capsule is known to play a role in the treatment of various types of cancer, however, it is not routinely indicated in the treatment of breast cancer. Only proceed once a doctor has prescribed the same because the treatment for breast cancer is nuanced.

Hodpro 50mg Capsule is known to affect fertility. Avoid Hodpro 50mg Capsule if you are trying to get pregnant. Please consult your doctor in case of any concerns.

Drug-Drug Interactions Checker List

  • ATOMOXETINE
  • BUSPIRONE
  • SUMATRIPTAN
  • PETHIDINE
  • METHADONE
  • TAPENTADOL
  • TRYPTOPHAN
  • RAMIPRIL
  • ENALAPRIL
  • LOSARTAN
  • PHENYTOIN
  • CARBAMAZEPINE
  • CLOZAPINE
  • FLUOXETINE
  • DULOXETINE
  • ENTACAPONE
  • LEVODOPA

Special Advise

  • Take Hodpro 50mg Capsule exactly as prescribed. 

  • In case you miss a dose of Hodpro 50mg Capsule , take it as soon as possible. However, revert to the original schedule if it is too close to the next dose. Do not ever take a double dose.

  • Please inform your doctor immediately if you accidentally take an extra dose of Hodpro 50mg Capsule . Some common symptoms of an overdose can be low blood pressure, slow pulse, shortness of breath, low blood sugar, fits, dizziness, feeling sick and discolouration of the skin.

  •  Do not discontinue taking Hodpro 50mg Capsule abruptly or without the advice of the physician.

  • Please know that your doctor may order blood tests to check your tolerance and need of Hodpro 50mg Capsule .

  • Avoid getting out in the sun after taking Hodpro 50mg Capsule and if you do, make sure you use a potent sunscreen and wear protective clothing.

Disease/Condition Glossary

Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.

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