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  3. Hydrazide 12.5 mg Tablet 10's

Hydrazide 12.5 mg Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

HYDROCHLOROTHIAZIDE-12.5MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hydrazide 12.5 mg Tablet

Hydrazide 12.5 mg Tablet belongs to a group of medicines called diuretics (which increase urine production). It is used to treat high blood pressure, heart failure and oedema (a build-up of fluid in the body). Diuretics are sometimes called 'water pills' because they make you urinate more. Besides this Hydrazide 12.5 mg Tablet is also sometimes used to help you urinate when your kidneys aren't working properly. High blood pressure or hypertension is a chronic condition in which the force exerted by the blood against the artery wall is high. The higher this blood pressure, the harder the heart has to pump. As a result, it leads to heart diseases, irregular heartbeat, and other complications. Oedema (swelling) may occur in case of high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs.

Hydrazide 12.5 mg Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

You can take Hydrazide 12.5 mg Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Sometimes, you may experience dehydration, headache, nausea, or dizziness. Most of these side effects of Hydrazide 12.5 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking the Hydrazide 12.5 mg Tablet  of your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of heart disease and stroke. Inform your doctor if you are suffering from kidney, liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Hydrazide 12.5 mg Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to Hydrazide 12.5 mg Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body.

Uses of Hydrazide 12.5 mg Tablet

Hypertension (high blood pressure), Oedema.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

When you take Hydrazide 12.5 mg Tablet , the blood vessels in your body will be relaxed, which will help lower the blood pressure. Also, it relaxes the blood vessels and helps to improve the blood flow. It helps in losing out excess fluids from the body by increasing the production of urine. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. Besides, this relieves oedema and helps you carry out your daily activities more efficiently.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before using Hydrazide 12.5 mg Tablet , tell your doctor if you have liver disease, kidney disease, eye problem (glaucoma), asthma, increased uric acid level (gout), diabetes, or allergic to antibiotics (like sulpha drugs or penicillin). Hydrazide 12.5 mg Tablet should not be given to the people allergic to Hydrazide 12.5 mg Tablet , have low blood pressure (less than 90 mm of Hg), or have had a heart attack, kidney disease, or liver disease. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding; your doctor will prescribe Hydrazide 12.5 mg Tablet only if the benefits outweigh the risk. Before taking the Hydrazide 12.5 mg Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
How does the drug interact with Hydrazide 12.5 mg Tablet:
Taking Cisapride and Hydrazide 12.5 mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Hydrazide 12.5 mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Hydrazide 12.5 mg Tablet:
Taking Dofetilide and Hydrazide 12.5 mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Hydrazide 12.5 mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Coadministration of Aminolevulinic acid with Hydrazide 12.5 mg Tablet can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Hydrazide 12.5 mg Tablet, it can be taken if advised by your doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideTizanidine
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
The combined use of Tizanidine and Hydrazide 12.5 mg Tablet can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Tizanidine and Hydrazide 12.5 mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Co-administration of Dolasetron and Hydrazide 12.5 mg Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dolasetron and Hydrazide 12.5 mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDroperidol
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Co-administration of Droperidol and Hydrazide 12.5 mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Droperidol and Hydrazide 12.5 mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Taking Ziprasidone and Hydrazide 12.5 mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Hydrazide 12.5 mg Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideLithium
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Coadministration of Lithium and Hydrazide 12.5 mg Tablet can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Hydrazide 12.5 mg Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Coadministration of Amiodarone together with Hydrazide 12.5 mg Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Hydrazide 12.5 mg Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideArsenic trioxide
Severe
How does the drug interact with Hydrazide 12.5 mg Tablet:
Co-administration of Arsenic trioxide and Hydrazide 12.5 mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Hydrazide 12.5 mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Hydrazide 12.5 mg Tablet Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

It is a medical term for fluid retention. Due to oedema, the affected area starts swelling up. If it does not subside, please consult your doctor immediately.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

Hydrazide 12.5 mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions and one should not abruptly discontinue it without discussing it with a doctor.

Yes, prolonged intake of Hydrazide 12.5 mg Tablet may decrease your potassium levels in the bloodstream. So, it is better to ask your doctor about foods high in potassium like bananas or orange juice. Besides this, consult a doctor regarding the use of table salt or sodium chloride or salt substitute containing potassium.

Hydrazide 12.5 mg Tablet may make you more skin more sensitive to the sun and may also increase your risk for skin cancer if used for a long time. Try to limit your time in the sun and avoid tanning booths and sunlamps. You can also use sunscreen and wear protective clothing when outdoors.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • ATORVASTATIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • The monitoring of serum electrolytes is particularly important while taking hydrochlorothiazide.

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

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