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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Whats That

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Composition :

IBUPROFEN-400MG

Manufacturer/Marketer :

Strava Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ibuprofen 400 mg Tablet

Ibuprofen 400 mg Tablet belongs to the group of medications called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) primarily used to relieve mild to moderate pain, inflammation, and fever in adults and paediatrics above 6 months of age. It helps to treat the conditions such as menstrual cramps, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, and flu symptoms.
 
Ibuprofen 400 mg Tablet contains 'Ibuprofen' which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation, and fever. 
 
Take Ibuprofen 400 mg Tablet as prescribed by your doctor. You are advised to take Ibuprofen 400 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as indigestion, diarrhoea, constipation, flatulence (gas), general weakness, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 
 
Ibuprofen 400 mg Tablet may increase the chances of stomach ulcers, bleeding and the risk of heart attack or stroke. Avoid or limit the intake of alcohol while taking Ibuprofen 400 mg Tablet . Consult your doctor before taking Ibuprofen 400 mg Tablet if you are pregnant or breastfeeding; your doctor will prescribe Ibuprofen 400 mg Tablet only if the benefits outweigh the risks. Ibuprofen 400 mg Tablet may cause drowsiness, so drive with caution. Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Ibuprofen 400 mg Tablet for 10 days, please consult your doctor. 

Uses of Ibuprofen 400 mg Tablet

Pain, Fever

Directions for Use

Tablet/capsule: Do not chew, break, or crush the tablet/capsule; swallow it as a whole with a glass of water. Syrup/Suspension/Drops: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Ibuprofen 400 mg Tablet belongs to the group of NSAIDs used to relieve pain and inflammation. Ibuprofen 400 mg Tablet relieves period pain, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, flu, and fever symptoms. Ibuprofen 400 mg Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Besides this, it also minimizes fever due to pain and inflammatory conditions. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Ibuprofen 400 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.

Drug Warnings

If you have had any recent heart bypass surgery (CABG), do not use Ibuprofen 400 mg Tablet . Ibuprofen 400 mg Tablet increases the chances of stomach ulcers and bleeding, so do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Ibuprofen 400 mg Tablet if you are pregnant or breastfeeding; your doctor will prescribe you Ibuprofen 400 mg Tablet only if the benefits outweigh the risks. Ibuprofen 400 mg Tablet may cause drowsiness, so drive with caution. Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. If your condition does not improve even after taking Ibuprofen 400 mg Tablet for 10 days, please consult your doctor. Avoid consuming alcohol with Ibuprofen 400 mg Tablet as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking Ibuprofen 400 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take aspirin or any other NSAIDs for pain relief along with Ibuprofen 400 mg Tablet unless prescribed by the doctor.

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Taking Ketorolac and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Ibuprofen 400 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Combining Meloxicam and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Ibuprofen 400 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTinzaparin
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Tinzaparin and Ibuprofen 400 mg Tablet can increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Tinzaparin and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMetrizamide
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Metrizamide and Ibuprofen 400 mg Tablet can cause kidney damage.

How to manage the interaction:
Co-administration of Metrizamide and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenOxaprozin
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Oxaprozin and Ibuprofen 400 mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Co-administration of Oxaprozin and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTenofovir alafenamide
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Tenofovir alafenamide and Ibuprofen 400 mg Tablet can cause kidney problems.

How to manage the interaction:
Co-administration of Tenofovir alafenamide and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenHuman immunoglobulin
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Taking Human immunoglobulin with Ibuprofen 400 mg Tablet may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Ibuprofen 400 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IbuprofenCabozantinib
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Cabozantinib and Ibuprofen 400 mg Tablet can increase the risk of bleeding.

How to manage the interaction:
using Cabozantinib and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenIomeprol
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
The combined use of Iomeprol and Ibuprofen 400 mg Tablet can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Iomeprol and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPiroxicam
Severe
How does the drug interact with Ibuprofen 400 mg Tablet 400 mg Tablet:
Use of Piroxicam with Ibuprofen 400 mg Tablet can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Co-administration of Piroxicam and Ibuprofen 400 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy. Apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Ibuprofen 400 mg Tablet Substitute

Substitutes safety advice
  • Brufen 400 Tablet 15's

    by Others

    1.20per tablet
  • Brufen 400 Tablet 20's

    by Others

    1.32per tablet
  • Ibupal 400mg Tablet

    by Others

    0.35per tablet
  • Iburin 400mg Tablet

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    0.60per tablet
  • Ibugrap 400mg Tablet

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    0.66per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ibuprofen 400 mg Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain and inflammation.

Diarrhoea or dehydration might be a side-effect of Ibuprofen 400 mg Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Ibuprofen 400 mg Tablet for more than 10 days unless prescribed by your doctor. Taking Ibuprofen 400 mg Tablet for longer durations or high doses may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.

Ibuprofen 400 mg Tablet may increase the risk of heart attack or stroke. Therefore, consult your doctor before taking Ibuprofen 400 mg Tablet if you have heart problems. Do not use Ibuprofen 400 mg Tablet immediately before or after bypass surgery like CABG.

Taking Ibuprofen 400 mg Tablet with or after food or milk may partially reduce stomach side effects such as indigestion.

Ibuprofen 400 mg Tablet can be used for relieving period pain and cramps if prescribed by the doctor. Do not exceed the dose and duration prescribed by your doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • MELOXICAM
  • FLUOXETINE

Disease/Condition Glossary

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and certain medical conditions.

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