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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

INDOMETHACIN-25MG

Manufacturer/Marketer :

Sterkem Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Inmecin-25 Tablet

Inmecin-25 Tablet belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmecin-25 Tablet is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery.

Inmecin-25 Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Inmecin-25 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, dizziness, diarrhoea, vomiting, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inmecin-25 Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Inmecin-25 Tablet . Inmecin-25 Tablet increases the chances of stomach ulcers and bleeding. To treat your condition effectually, continue taking Inmecin-25 Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Inmecin-25 Tablet if you are pregnant or breastfeeding unless prescribed. Inmecin-25 Tablet causes drowsiness and dizziness, so drive with caution. Inmecin-25 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Inmecin-25 Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Inmecin-25 Tablet

Osteoarthritis, Ankylosing spondylitis, Rheumatoid arthritis

Directions for Use

Take Inmecin-25 Tablet with or immediately after food or with milk or antacids. Take Inmecin-25 Tablet at the same time every day for best results. Tablet/Capsule: Swallow it as a whole with a glass of water or milk; do not chew, break, or crush the tablet. Oral liquid: Take the prescribed dose by mouth using the measuring cup provided by the pack; shake the pack well before each use.

Medicinal Benefits

Inmecin-25 Tablet belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs). Inmecin-25 Tablet is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmecin-25 Tablet is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery. Inmecin-25 Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Inmecin-25 Tablet

  • Headache,
  • Dizziness
  • Diarrhoea
  • Vomiting
  • Constipation

Drug Warnings

Inmecin-25 Tablet can increase your risk of having a fatal heart attack, chest pain (angina) or stroke. So, tell your doctor that you are using Inmecin-25 Tablet before undergoing heart bypass surgery (CABG) or graft surgery. Do not take Inmecin-25 Tablet if you are allergic to Inmecin-25 Tablet , have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Do not take Inmecin-25 Tablet if you are pregnant or breastfeeding unless prescribed. Inmecin-25 Tablet causes drowsiness and dizziness, so drive only if you are alert. Inmecin-25 Tablet should not be given to children as the safety have not been established. Avoid consuming alcohol along with Inmecin-25 Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Inmecin-25 Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach like blood in stools.

Drug-Drug Interactions

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IndometacinCidofovir
Critical
IndometacinKetorolac
Critical

Drug-Drug Interactions

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IndometacinCidofovir
Critical
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inmecin-25 Tablet with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinKetorolac
Critical
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inmecin-25 Tablet with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinAdefovir dipivoxil
Severe
How does the drug interact with Inmecin-25 Tablet:
Using Indomethacin with Adefovir dipivoxil can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Inmecin-25 Tablet with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, bone pain, muscle cramps, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.
IndometacinWarfarin
Severe
How does the drug interact with Inmecin-25 Tablet:
Using Warfarin together with Inmecin-25 Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Inmecin-25 Tablet and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
IndometacinFlurbiprofen
Severe
How does the drug interact with Inmecin-25 Tablet:
Taking Indomethacin with Flurbiprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulceration.

How to manage the interaction:
Taking Inmecin-25 Tablet with Flurbiprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinHuman immunoglobulin
Severe
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Human immunoglobulin with Inmecin-25 Tablet may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Indomethacin can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IndometacinTenofovir disoproxil
Severe
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Indomethacin with Tenofovir disoproxil can increase the risk of developing kidney injury.

How to manage the interaction:
There may be a possibility of interaction between Tenofovir disoproxil and Inmecin-25 Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, weakness, and irregular heartbeat, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinIbrutinib
Severe
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Indomethacin with Ibrutinib can increase the likelihood and seriousness of side effects.

How to manage the interaction:
Taking Inmecin-25 Tablet with Ibrutinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinSirolimus
Severe
How does the drug interact with Inmecin-25 Tablet:
Co-administration of Indomethacin with Sirolimus can increase the risk or severity of kidney damage.

How to manage the interaction:
Although taking Inmecin-25 Tablet and Sirolimus together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, breathing difficulty, muscle cramps, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
IndometacinDabigatran etexilate
Severe
How does the drug interact with Inmecin-25 Tablet:
Using Indomethacin with Dabigatran etexilate can increase the risk of bleeding.

How to manage the interaction:
Taking Inmecin-25 Tablet with Dabigatran etexilate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

GOUT THERAPY

Inmecin-25 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Inmecin-25 Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.

Inmecin-25 Tablet causes drowsiness, dizziness, tiredness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

Diarrhoea might be a side-effect of Inmecin-25 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Inmecin-25 Tablet for longer durations or high doses as it may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.

Inmecin-25 Tablet may increase the risk of heart attack or stroke. Do not use Inmecin-25 Tablet immediately before or after heart surgery. Consult your doctor before taking Inmecin-25 Tablet if you have/ had heart problems.

Avoid or limit consumption of alcohol with Inmecin-25 Tablet as it increases the chances of stomach ulcers and bleeding.

Inmecin-25 Tablet may affect laboratory test results. Inform the person doing the tests that you are taking Inmecin-25 Tablet .

Inmecin-25 Tablet may affect fertility. However, the effect is reversible on stopping Inmecin-25 Tablet . Consult your doctor before taking Inmecin-25 Tablet if you are planning to become pregnant. It is important not to become pregnant while using Inmecin-25 Tablet and for at least 1 month after stopping Inmecin-25 Tablet as it can cause harm to the unborn baby or fetus. Women can be given a reminder card from the doctor about this.

The common side effects of Inmecin-25 Tablet include skin becoming more sensitive to sunlight, dry eyes, dry throat, dry nose and nosebleeds, headaches and general aches and pains. Besides this, in the rare case, it can cause depression and even make people feel suicidal.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ASPIRIN
  • DULOXETINE
  • METOPROLOL
  • CELECOXIB
  • PREDNISONE

Special Advise

  • Your doctor may advise you to undergo tests for monitoring liver and kidney functioning, blood cell levels, effect on stomach and intestine.
  • Regular monitoring of eye-sight via eye tests is advised if you have rheumatoid arthritis.
  • Monitoring of blood pressure levels and heart functioning is recommended.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, inflammation, stiffness, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear-out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include stiffness, pain, swelling, deformities and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine, which starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain and back and joints. 

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