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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Composition :

INDOMETHACIN-50MG

Manufacturer/Marketer :

Sterkem Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Inmecin 50 Capsule

Inmecin 50 Capsule belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmecin 50 Capsule is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery.

Inmecin 50 Capsule works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Inmecin 50 Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, dizziness, diarrhoea, vomiting, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inmecin 50 Capsule can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Inmecin 50 Capsule . Inmecin 50 Capsule increases the chances of stomach ulcers and bleeding. To treat your condition effectually, continue taking Inmecin 50 Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Inmecin 50 Capsule if you are pregnant or breastfeeding unless prescribed. Inmecin 50 Capsule causes drowsiness and dizziness, so drive with caution. Inmecin 50 Capsule should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Inmecin 50 Capsule as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Inmecin 50 Capsule

Osteoarthritis, Ankylosing spondylitis, Rheumatoid arthritis

Directions for Use

Take Inmecin 50 Capsule with or immediately after food or with milk or antacids. Take Inmecin 50 Capsule at the same time every day for best results. Tablet/Capsule: Swallow it as a whole with a glass of water or milk; do not chew, break, or crush the tablet. Oral liquid: Take the prescribed dose by mouth using the measuring cup provided by the pack; shake the pack well before each use.

Medicinal Benefits

Inmecin 50 Capsule belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs). Inmecin 50 Capsule is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmecin 50 Capsule is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, pain following joint and bone surgery. Inmecin 50 Capsule works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight
Side effects of Inmecin 50 Capsule
  • Prefer liquid food like juices and soups when you are not likely to eat.
  • Avoid spicy, fatty and fried foods as they cause stomach upset.
  • Eat small and frequent meals, avoiding large meals at a time.
  • Add healthy foods in your diet like fruits and vegetables.
  • Take starchy food like cereals, bread and potatoes etc.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Syncope (Loss of consciousness): A Step-by-Step Guide:
  • Let someone you trust know about your medication and the potential risk of loss of consciousness. Ask them to check on you regularly.
  • If you experience loss of consciousness or feel faint, call emergency services or have someone take you to the hospital.
  • Once you're receiving medical attention, inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your doctor may adjust your treatment plan by changing dosage, switching to a different medication, or stopping the medication.
  • Wear a medical alert device, such as a smartwatch or pendant, that can detect falls or other emergencies and alert emergency services.
  • If you're concerned about the risk of loss of consciousness, consult your doctor before it happens to develop a plan to mitigate the risk.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Include omega-3 rich foods in your diet to reduce inflammation.
  • Eat antioxidant-rich foods like fruits, vegetables, and nuts to promote overall skin health.
  • Stay hydrated by drinking plenty of water.
  • Maintain a healthy skin care routine, using gentle, fragrance-free products.
  • Wear loose, breathable clothing to minimize irritation.
  • Keep fingernails short and clean to prevent further skin damage.
  • Use a humidifier to add moisture to the air, reducing dryness and itchiness.
  • Practice stress-reducing techniques like meditation or deep breathing to manage stress levels.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug Warnings

Inmecin 50 Capsule can increase your risk of having a fatal heart attack, chest pain (angina) or stroke. So, tell your doctor that you are using Inmecin 50 Capsule before undergoing heart bypass surgery (CABG) or graft surgery. Do not take Inmecin 50 Capsule if you are allergic to Inmecin 50 Capsule , have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Do not take Inmecin 50 Capsule if you are pregnant or breastfeeding unless prescribed. Inmecin 50 Capsule causes drowsiness and dizziness, so drive only if you are alert. Inmecin 50 Capsule should not be given to children as the safety have not been established. Avoid consuming alcohol along with Inmecin 50 Capsule as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Inmecin 50 Capsule and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach like blood in stools.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Inmecin 50 Capsule:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inmecin 50 Capsule with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inmecin 50 Capsule with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
Using Indomethacin with Enoxaparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Inmecin 50 Capsule with Enoxaparin together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinDicoumarol
Severe
How does the drug interact with Inmecin 50 Capsule:
Using Inmecin 50 Capsule with Dicoumarol could make you bleed more readily.

How to manage the interaction:
Taking Inmecin 50 Capsule with Dicoumarol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
Coadministration of Ketoconazole and Inmecin 50 Capsule may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Inmecin 50 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
The combined use of diclofenac and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Diclofenac and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
Taking indomethacin with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between fondaparinux and Inmecin 50 Capsule, it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Inmecin 50 Capsule:
The combined use of Inmecin 50 Capsule and Ibuprofen can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Inmecin 50 Capsule and Ibuprofen together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Inmecin 50 Capsule:
Co-administration of Human immunoglobulin with Inmecin 50 Capsule may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Indomethacin can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Inmecin 50 Capsule:
Using Indomethacin with Dabigatran etexilate can increase the risk of bleeding.

How to manage the interaction:
Taking Inmecin 50 Capsule with Dabigatran etexilate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

GOUT THERAPY

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Inmecin 50 Capsule works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.

Inmecin 50 Capsule causes drowsiness, dizziness, tiredness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

Diarrhoea might be a side-effect of Inmecin 50 Capsule . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Inmecin 50 Capsule for longer durations or high doses as it may cause a heart attack or stroke. Do not exceed the dose and duration prescribed by your doctor.

Inmecin 50 Capsule may increase the risk of heart attack or stroke. Do not use Inmecin 50 Capsule immediately before or after heart surgery. Consult your doctor before taking Inmecin 50 Capsule if you have/ had heart problems.

Avoid or limit consumption of alcohol with Inmecin 50 Capsule as it increases the chances of stomach ulcers and bleeding.

Inmecin 50 Capsule may affect laboratory test results. Inform the person doing the tests that you are taking Inmecin 50 Capsule .

Inmecin 50 Capsule may affect fertility. However, the effect is reversible on stopping Inmecin 50 Capsule . Consult your doctor before taking Inmecin 50 Capsule if you are planning to become pregnant. It is important not to become pregnant while using Inmecin 50 Capsule and for at least 1 month after stopping Inmecin 50 Capsule as it can cause harm to the unborn baby or fetus. Women can be given a reminder card from the doctor about this.

The common side effects of Inmecin 50 Capsule include skin becoming more sensitive to sunlight, dry eyes, dry throat, dry nose and nosebleeds, headaches and general aches and pains. Besides this, in the rare case, it can cause depression and even make people feel suicidal.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ASPIRIN
  • DULOXETINE
  • METOPROLOL
  • CELECOXIB
  • PREDNISONE

Special Advise

  • Your doctor may advise you to undergo tests for monitoring liver and kidney functioning, blood cell levels, effect on stomach and intestine.
  • Regular monitoring of eye-sight via eye tests is advised if you have rheumatoid arthritis.
  • Monitoring of blood pressure levels and heart functioning is recommended.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, inflammation, stiffness, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear-out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include stiffness, pain, swelling, deformities and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine, which starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain and back and joints. 

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