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  1. Home
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  3. Inmeth 50 mg Suppositories 5's

Inmeth 50 mg Suppositories 5's, Pack of 5 SuppositoryS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Whats That

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Composition :

INDOMETHACIN-50MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About Inmeth 50 mg Suppositories

Inmeth 50 mg Suppositories belongs to the group of pain killers known as NSAID's (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth 50 mg Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder).

Inmeth 50 mg Suppositories contains 'Indomethacin' that works by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Inmeth 50 mg Suppositories for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as headache, dizziness, indigestion, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you have had any recent heart surgery, do not use Inmeth 50 mg Suppositories as it may increase the risk of heart attack or stroke. Inmeth 50 mg Suppositories may also increase the chances of stomach ulcers and bleeding. Do not use Inmeth 50 mg Suppositories if you are pregnant or breastfeeding unless prescribed. Inmeth 50 mg Suppositories may cause dizziness, so drive with caution. Inmeth 50 mg Suppositories is not recommended for children below 14 years as safety and efficacy have not been established. Avoid consuming alcohol along with Inmeth 50 mg Suppositories as it could lead to increased dizziness; it might also increase the risk of stomach bleeding.

Uses of Inmeth 50 mg Suppositories

Osteoarthritis, Ankylosing spondylitis, Rheumatoid arthritis

Directions for Use

Check the label for directions before use. Lie down on your left side and raise your right knee to the chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Wash your hands thoroughly after use.

Medicinal Benefits

Inmeth 50 mg Suppositories belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Inmeth 50 mg Suppositories is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis such as stiffness, swelling and joint pain. Inmeth 50 mg Suppositories is also used to treat acute gouty arthritis and bursitis and/or tendinitis (painful shoulder). Inmeth 50 mg Suppositories works by blocking the effect of chemical messengers known as cyclo-oxygenase (COX) enzymes. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight
Side effects of Inmeth 50 mg Suppositories
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Drug Warnings

Do not take Inmeth 50 mg Suppositories if you are allergic to Inmeth 50 mg Suppositories. Inform your doctor if you are due to undergo heart bypass surgery (CABG) or graft surgery, have severe heart failure, history of proctitis (inflammation of the lining of the rectum) or recent rectal bleeding, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any pain killers or if you have liver or kidney problems. Do not take Inmeth 50 mg Suppositories if you are pregnant or breastfeeding unless prescribed. Inmeth 50 mg Suppositories causes dizziness, so drive only if you are alert. Inmeth 50 mg Suppositories is not recommended for children as safety has not been established. Avoid consuming alcohol along with Inmeth 50 mg Suppositories as it could lead to increased dizziness and might increase the risk of stomach bleeding. Stop taking Inmeth 50 mg Suppositories and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach like blood in stools.

Drug-Drug Interactions

verifiedApollotooltip
IndometacinKetorolac
Critical
IndometacinCidofovir
Critical

Drug-Drug Interactions

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IndometacinKetorolac
Critical
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinCidofovir
Critical
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinGlimepiride
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Taking indomethacin with glimepiride may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with indomethacin if prescribed by the doctor. Consult the doctor if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat.
IndometacinDicoumarol
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Using Inmeth 50 mg Suppositories with Dicoumarol could make you bleed more readily.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Dicoumarol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinSirolimus
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Indomethacin with Sirolimus can increase the risk or severity of kidney damage.

How to manage the interaction:
Although taking Inmeth 50 mg Suppositories and Sirolimus together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, breathing difficulty, muscle cramps, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
IndometacinEnoxaparin
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Using Indomethacin with Enoxaparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Enoxaparin together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinPiroxicam
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Use of Inmeth 50 mg Suppositories with Piroxicam can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Piroxicam together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinTenofovir alafenamide
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Co-administration of Indomethacin with Tenofovir alafenamide may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Inmeth 50 mg Suppositories with Tenofovir alafenamide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, lack of appetite, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, breathing difficulty, cramping in the muscles, disorientation, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medications without consulting a doctor.
IndometacinTacrolimus
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Taking Tacrolimus with Indomethacin may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and indomethacin together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, breathing difficulty, muscle cramps, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
IndometacinFlucytosine
Severe
How does the drug interact with Inmeth 50 mg Suppositories:
Coadministration of Flucytosine with Indomethacin can increase the risk of developing infections.

How to manage the interaction:
Although there is a possible interaction between Flucytosine and Inmeth 50 mg Suppositories, you can take these medicines together if prescribed by your doctor. Contact a doctor if you experience fever, muscle ache, sore throat, or shortness of breath. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Inmeth 50 mg Suppositories works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.

Diarrhoea might be a side-effect of Inmeth 50 mg Suppositories. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Inmeth 50 mg Suppositories for longer durations or high doses as it may increase the risk of stomach bleeding. Do not exceed the dose and duration prescribed by your doctor.

Inmeth 50 mg Suppositories may increase the risk of heart attack or stroke. Do not use Inmeth 50 mg Suppositories immediately before or after heart surgery. Consult your doctor before using Inmeth 50 mg Suppositories if you have/ had heart problems.

Inmeth 50 mg Suppositories may affect laboratory test results. Inform the person doing the tests that you are using Inmeth 50 mg Suppositories.

Inmeth 50 mg Suppositories may affect fertility. However, the effect is reversible on stopping Inmeth 50 mg Suppositories. Consult your doctor before using Inmeth 50 mg Suppositories if you are planning to become pregnant.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • FUROSEMIDE
  • DIGOXIN

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, inflammation, stiffness, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include stiffness, pain, swelling, deformities and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine, which starts in the lower back and can spread to the neck, joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain in the back and joints. 

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